Search Results - "Sowmya, Gopichandran"

Protein-protein interactions and prediction: a comprehensive overview by Sowmya, Gopichandran, Ranganathan, Shoba

“…Molecular function in cellular processes is governed by protein-protein interactions (PPIs) within biological networks. Selective yet specific association of…”
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Discrete structural features among interface residue-level classes by Sowmya, Gopichandran, Ranganathan, Shoba

“…Protein-protein interaction (PPI) is essential for molecular functions in biological cells. Investigation on protein interfaces of known complexes is an…”
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Linking structural features of protein complexes and biological function by Sowmya, Gopichandran, Breen, Edmond J., Ranganathan, Shoba

“…Protein–protein interaction (PPI) establishes the central basis for complex cellular networks in a biological cell. Association of proteins with other proteins…”
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A site for direct integrin αvβ6·uPAR interaction from structural modelling and docking by Sowmya, Gopichandran, Khan, Javed Mohammed, Anand, Samyuktha, Ahn, Seong Beom, Baker, Mark S., Ranganathan, Shoba

“…Integrin αvβ6 is an epithelially-restricted heterodimeric transmembrane glycoprotein, known to interact with the urokinase plasminogen activating receptor…”
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Characterization of the Interaction between Heterodimeric αvβ6 Integrin and Urokinase Plasminogen Activator Receptor (uPAR) Using Functional Proteomics by Ahn, Seong Beom, Mohamedali, Abidali, Anand, Samyuktha, Cheruku, Harish R, Birch, Debra, Sowmya, Gopichandran, Cantor, David, Ranganathan, Shoba, Inglis, David W, Frank, Ronald, Agrez, Michael, Nice, Edouard C, Baker, Mark S

“…Urokinase plasminogen activator receptor (uPAR) and the epithelial integrin αvβ6 are thought to individually play critical roles in cancer metastasis. These…”
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Insights from the structural analysis of protein heterodimer interfaces by Sowmya, Gopichandran, Anita, Sathyanarayanan, Kangueane, Pandjassarame

“…Protein heterodimer complexes are often involved in catalysis, regulation, assembly, immunity and inhibition. This involves the formation of stable interfaces…”
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Interaction modes at protein hetero-dimer interfaces by Vaishnavi, Ayyappan, Sowmya, Gopichandran, Kalaivanii, Jayaseelan, Ilakya, Selvarajan, Kangueane, Uma, Kangueane, Pandjassarame

“…Hetero dimer (different monomers) interfaces are involved in catalysis and regulation through the formation of interface active sites. This is critical in cell…”
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HIV-1 envelope accessible surface and polarity: clade, blood, and brain by Sowmya, Gopichandran, Shamini, Gunasagaran, Anita, Sathyanarayanan, Sakharkar, Meena, Mathura, Venkat, Rodriguez, Hector, Levine, Andrew J, Singer, Elyse, Commins, Deborah, Somboonwit, Charurut, Sinnott, John T, Sidhu, Harcharan S, Rajaseger, Ganapathy, Pushparaj, Peter Natesan, Kangueane, Pandajarasamme, Shapshak, Paul

“…The human immunodeficiency virus type-1 (HIV-1) gp160 (gp120-gp41 complex) trimer envelope (ENV) protein is a potential vaccine candidate for HIV/AIDS. HIV-1…”
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