Search Results - "Sowa, Alexandra R"
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The Effects of Intramuscular Naloxone Dose on Mu Receptor Displacement of Carfentanil in Rhesus Monkeys
Published in Molecules (Basel, Switzerland) (17-03-2020)“…Naloxone (NLX) is a mu receptor antagonist used to treat acute opioid overdoses. Currently approved doses of naloxone to treat opioid overdoses are 4 mg…”
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Use of 55 PET radiotracers under approval of a Radioactive Drug Research Committee (RDRC)
Published in EJNMMI radiopharmacy and chemistry (11-11-2020)“…Background In the US, EU and elsewhere, basic clinical research studies with positron emission tomography (PET) radiotracers that are generally recognized as…”
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Classics in Neuroimaging: Imaging the Cholinergic System with Positron Emission Tomography
Published in ACS chemical neuroscience (05-05-2021)“…Since the earliest days of nuclear medicine, there has been interest in using PET and SPECT imaging to interrogate and quantify the cholinergic system. In this…”
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Futureproofing [18F]Fludeoxyglucose manufacture at an Academic Medical Center
Published in EJNMMI radiopharmacy and chemistry (05-10-2018)“…Background We recently upgraded our [ 18 F]fludeoxyglucose (FDG) production capabilities with the goal of futureproofing our FDG clinical supply, expanding the…”
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Classics in Neuroimaging: Development of Positron Emission Tomography Tracers for Imaging the GABAergic Pathway
Published in ACS chemical neuroscience (15-07-2020)“…Advances in drug discovery and diverse radiochemical methodologies have led to the discovery of novel positron emission tomography (PET) radiotracers used to…”
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A spot test for determination of residual TBA levels in 18 F-radiotracers for human use using Dragendorff reagent
Published in Analytical methods (30-10-2020)“…When utilizing [ F]tetrabutylammonium fluoride ([ F]TBAF) in the synthesis of F-labeled radiotracers for clinical positron emission tomography (PET) imaging,…”
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Development of Positron Emission Tomography Radiotracers for the GABA Transporter 1
Published in ACS chemical neuroscience (21-11-2018)“…In vivo positron emission tomography (PET) imaging of the γ-aminobutyric acid (GABA) receptor complex has been accomplished using radiolabeled benzodiazepine…”
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Fluorine-18 patents (2009-2015). Part 2: new radiochemistry
Published in Pharmaceutical patent analyst (01-09-2016)“…Fluorine-18 ( F) is one of the most common positron-emitting radionuclides used in the synthesis of positron emission tomography radiotracers due to its ready…”
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9
Classics in Neuroimaging: Development of PET Tracers for Imaging the GABAergic pathway
Published in ACS chemical neuroscience (24-06-2020)“…Advances in drug discovery and diverse radiochemical methodologies have led the discovery of novel positron emission tomography (PET) radiotracers to image the…”
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