Search Results - "Souza Wyse, Angela Terezinha"
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Intrastriatal hypoxanthine reduces Na(+),K (+)-ATPase activity and induces oxidative stress in the rats
Published in Metabolic brain disease (01-03-2007)“…The main objective of this study was to investigate the effects of a single intrastriatal injection of hypoxanthine, a metabolite accumulated in Lesch Nyhan…”
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2
Promotion of oxidative stress by l-tryptophan in cerebral cortex of rats
Published in Neurochemistry international (01-07-2006)“…Despite the significant brain abnormalities, the neurotoxic mechanisms of brain injury in hypertryptophanemia are virtually unknown. In this work, it was…”
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3
Chronic methylphenidate administration alters antioxidant defenses and butyrylcholinesterase activity in blood of juvenile rats
Published in Molecular and cellular biochemistry (01-02-2012)“…Methylphenidate (MPH), a psychostimulant that affects both dopaminergic and noradrenergic systems, is one of the most frequently prescribed treatments for…”
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4
Experimental evidence of oxidative stress in plasma of homocystinuric patients: A possible role for homocysteine
Published in Molecular genetics and metabolism (01-09-2011)“…Homocystinuria is an inherited disorder biochemically characterized by high urinary excretion of homocystine and increased levels of homocysteine (Hcy) and…”
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5
Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl ester
Published in Pediatric nephrology (Berlin, West) (01-08-2007)“…Cystinosis is a systemic genetic disease caused by a lysosomal transport deficiency accumulating cystine in most tissues. Although tissue damage might depend…”
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6
Protective effect of antioxidants on blood oxidative stress caused by arginine
Published in Fundamental & clinical pharmacology (01-04-2012)“…In this study, we investigated in vivo and in vitro effect of arginine on parameters of oxidative stress namely thiobarbituric acid‐reactive substances…”
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Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats
Published in Metabolic brain disease (01-06-2010)“…5-Oxoproline accumulates in glutathione synthetase deficiency, an autossomic recessive inherited disorder clinically characterized by hemolytic anemia,…”
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8
Chronic hyperprolinemia provokes a memory deficit in the Morris water maze task
Published in Metabolic brain disease (01-03-2005)“…In the present study we investigated the effect of chronic proline (Pro) administration on rat performance in the Morris water maze task. Rats received s.c…”
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9
In vivo and in vitro effects of proline on some parameters of oxidative stress in rat brain
Published in Brain research (21-11-2003)“…Hyperprolinemia type II is an autosomal recessive disorder caused by the severe deficiency of Δ 1-pyrroline-5-carboxylate dehydrogenase activity leading to…”
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10
Homocysteine and other markers of cardiovascular risk during a manic episode in patients with bipolar disorder
Published in Revista brasileira de psiquiatria (01-04-2013)“…To evaluate serum levels of different biomarkers associated with cardiovascular disease in patients with bipolar disorder (BD). Patients were prospectively…”
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11
In vitro effect of quinolinic acid on energy metabolism in brain of young rats
Published in Neuroscience research (01-02-2007)“…Quinolinic acid (QA) is found at increased concentrations in brain of patients affected by various common neurodegenerative disorders, including Huntington's…”
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12
Hyperhomocysteinemia selectively alters expression and stoichiometry of intermediate filament and induces glutamate‐ and calcium‐mediated mechanisms in rat brain during development
Published in International journal of developmental neuroscience (01-02-2010)“…The aim of the present work was to investigate the actions of a chemically induced chronic hyperhomocysteinemia model on intermediate filaments (IFs) of…”
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13
Neostigmine treatment induces neuroprotection against oxidative stress in cerebral cortex of asthmatic mice
Published in Metabolic brain disease (01-06-2020)“…During chronic inflammatory disease, such asthma, leukocytes can invade the central nervous system (CNS) and together with CNS-resident cells, generate…”
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14
Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase
Published in PloS one (13-02-2012)“…Macrophages are key elements in the inflammatory process, whereas depending on the micro-environmental stimulation they exhibit a pro-inflammatory…”
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15
Evidence that 3‐hydroxyisobutyric acid inhibits key enzymes of energy metabolism in cerebral cortex of young rats
Published in International journal of developmental neuroscience (01-05-2008)“…3‐Hydroxyisobutyric aciduria is an inherited metabolic disease caused by 3‐hydroxyisobutyryl‐CoA dehydrogenase deficiency. Tissue accumulation and high urinary…”
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16
Effects In Vitro of Guanidinoacetate on Adenine Nucleotide Hydrolysis and Acetylcholinesterase Activity in Tissues from Adult Rats
Published in Neurochemical research (01-06-2008)“…Guanidinoacetate methyltransferase (GAMT) deficiency is a disorder of creatine metabolism characterized by low plasma creatine concentrations in combination…”
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17
Recombinant human deoxyribonuclease attenuates oxidative stress in a model of eosinophilic pulmonary response in mice
Published in Molecular and cellular biochemistry (01-02-2016)“…The inflammatory cells infiltrating the airways produce several mediators, such as reactive oxygen species (ROS). ROS and the oxidant-antioxidant imbalance…”
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18
Alpha-tocopherol and ascorbic acid administration prevents the impairment of brain energy metabolism of hyperargininemic rats
Published in Cellular and molecular neurobiology (01-03-2006)“…1. We have previously demonstrated that arginine administration induces oxidative stress and compromises energy metabolism in rat hippocampus. In the present…”
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19
The effects of the interactions between amino acids on pyruvate kinase activity from the brain cortex of young rats
Published in International journal of developmental neuroscience (01-10-2005)“…Considering that pyruvate kinase activity, a crucial enzyme for glucose metabolism and energy liberation in brain, may be regulated by some amino acids, it is…”
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20
Forced Treadmill Exercise Prevents Spatial Memory Deficits in Aged Rats Probably Through the Activation of Na+, K+-ATPase in the Hippocampus
Published in Neurochemical research (01-05-2017)“…Regular physical activity has shown to improve the quality of life and to prevent age-related memory deficits. Memory processing requires proper regulation of…”
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