Search Results - "Souza Filho, José Dias"

A Comprehensive View on (−)‐7‐Oxo‐ent‐kaur‐16‐en‐19‐oic Acid, the Major Constituent of Xylopia sericea Leaves Extract: Complete NMR Assignments, X‐Ray Crystallographic Structure, in Vitro Antimalarial Activity and Cytotoxicity by Costa Gontijo, Douglas, Fernanda Alves do Nascimento, Maria, Borgati, Tatiane Freitas, Speziali, Nivaldo Lúcio, Dias de Souza Filho, José, Braga de Oliveira, Alaíde

“…Bioguided fractionation of Xylopia sericea antiplasmodial dichloromethane leaves extract led to the isolation of (−)‐7‐oxo‐ent‐kaur‐16‐en‐19‐oic acid…”
Get full text

The first report on flavonoid isolation from Annona crassiflora Mart by Lage, Gisele Avelar, Medeiros, Felipe da Silva, Furtado, Werônica de Lima, Takahashi, Jacqueline Aparecida, Filho, José Dias de Souza, Pimenta, Lúcia Pinheiro Santos

“…Annona crassiflora, a native tree from Brazilian Cerrado, is reported to possess several ethnomedical uses. Here, we report the isolation and unambiguous…”
Get full text

Bioguided isolation of myricetin-3-O-β-galactopyranoside with antinociceptive activity from the aerial part of Davilla elliptica St.-Hil by Campos, Jussara Júlia, de Oliveira Azevedo, Adolfo, de Souza Filho, José Dias, Castro Perez, Andrea, Castro Braga, Fernão

“…Davilla elliptica St.-Hil. (Dilleniaceae) is a medicinal plant traditionally used in Brazil to treat inflammatory processes, to relieve pain, as diuretic,…”
Get full text

Cytotoxic activity of extracts from Tecoma species and isolated lignans by Reis, Adriana Cotta Cardoso, Silva, Breno Mello, Souza Filho, José Dias, Pereira, Guilherme Rocha, Brandão, Geraldo Célio

“…Abstract A phytochemical study of Tecoma genus (Bignoniaceae) was accomplished by antitumor activity of ethanolic extracts. Species of this genus are composed…”
Get full text

Biotransformation of 21-O-acetyl-deoxycorticosterone by cell suspension cultures of Digitalis lanata (strain W.1.4) by de Pádua, Rodrigo Maia, Meitinger, Nadine, Filho, José Dias de Souza, Waibel, Reiner, Gmeiner, Peter, Braga, Fernão Castro, Kreis, Wolfgang

“…Reaction of the biotransformation of 21-O-acetyl-deoxycorticosterone (1) by Digitalis lanata cell suspension. The biotransformation of…”
Get full text

Chromatographic profile of xanthones and flavonoids in the anti-dengue extracts of Fridericia samydoides (Cham.) L.G. Lohmann (Bignoniaceae) by Fonseca, Juliane Morais da, Reis, Adriana Cotta Cardoso, Pereira, Guilherme Rocha, Moura, Hélia Maria Marques de, Souza Filho, José Dias, Silva, Breno de Mello, Brandão, Geraldo Célio

“…Abstract The flavonoids and xanthones present in the ethanol extracts of leaves and stems of Fridericia samydoides showed that anti-dengue activities in vitro…”
Get full text

Structure modifications of 2-phenylquinoline by Aspergillus genera produce novel derivatives with potent leishmanicidal and anti-inflammatory properties by Mischiatti, Keylla Lençone, Pimentel, Ida Chapaval, Donatti, Lucélia, Filho, José Dias de Souza, Porsani, Mariana Vieira, de Oliveira, Brás Heleno, Weffort-Santos, Almeriane Maria

“…•Biotransformation of 2-phenylquinoline by microorganisms was used as a strategy to obtain quinolinic derivatives as anti-leishmania…”
Get full text

Synthesis of 4-(Methoxycarbonyl)phenyl β-Lactoside Derivatives Modified at C(6) or C(6′), and Evaluation of Their Inhibitory Activity on Erythrina cristagalli Lectin-Mediated Hemagglutination by Butera, Anna Paola, de Souza Filho, José Dias, Prado, Maria Auxiliadôra Fontes, Lisboa, Marilda Pereira, Alves, Ricardo José

“…We report herein the synthesis of 4‐(methoxycarbonyl)phenyl β‐lactoside and eight derivatives modified at C(6) or C(6′). These compounds were evaluated in…”
Get full text

Chemical Analysis of Eruca sativa Ethanolic Extract and Its Effects on Hyperuricaemia by Teixeira, Arthur Ferrari, de Souza, Jacqueline, Dophine, Douglas Daniel, de Souza Filho, José Dias, Saúde-Guimarães, Dênia Antunes

“…In vivo assays and chemical analyses were performed on the ethanolic extract from leaves of . UHPLC-ESI-QTOF analysis confirmed the presence of glucosinolates…”
Get full text

Development and characterization of liposomal formulations containing sesquiterpene lactones for the treatment of chronic gout by Cunha Matosinhos, Rafaela, Frézard, Frédéric, Mendes Silva Araújo, Sabrina, Magalhães Barbosa, Andressa, de Souza, Isabela Fernanda, de Souza Filho, José Dias, de Souza, Jacqueline, Corrêa Oliveira Bahia, Ana Paula, Ietta, Francesca, Magnani, Agnese, Saúde-Guimarães, Dênia Antunes

“…Gout and hyperuricemia are characterized by high uric acid levels, and their treatment involves medications that have adverse effects. In this study, we…”
Get full text

Strychnos pseudoquina and Its Purified Compounds Present an Effective In Vitro Antileishmanial Activity by Lopes, Amanda de Santana, de Andrade, Pedro Henrique Rocha, Lage, Paula Sousa, Chávez Fumagalli, Miguel Angel, Valadares, Diogo Garcia, Duarte, Mariana Costa, Pagliara Lage, Daniela, Costa, Lourena Emanuele, Martins, Vivian Tamietti, Ribeiro, Tatiana Gomes, Filho, José Dias de Souza, Tavares, Carlos Alberto Pereira, Pádua, Rodrigo Maia de, Leite, João Paulo Viana, Coelho, Eduardo Antonio Ferraz

“…The development of new and cost-effective alternative therapeutic strategies to treat leishmaniasis has become a high priority. In the present study, the…”
Get full text

Metabolic Profile Changes in Mangalarga Marchador Horses Subjected to A Hypercaloric Diet Evaluated by Proton NMR Spectroscopy by Duarte, Patricia de Castro, Ribeiro, Rodrigo Martins, Machado, Alan Rodrigues Teixeira, Faleiros, Rafael Resende, Pimenta, Lúcia Pinheiro Santos, Filho, José Dias de Souza

“…•Serum metabolomic changes was assessed in Mangalarga Marchador horses for the first time•Metabolomic changes were detected in the serum of horses subjected to…”
Get full text

The catalytic mechanism of the 3-ketosteroid isomerase of Digitalis lanata involves an intramolecular proton transfer and the activity is not associated with the 3β-hydroxysteroid dehydrogenase activity by Meitinger, Nadine, Munkert, Jennifer, Maia de Pádua, Rodrigo, de Souza Filho, José Dias, Maid, Harald, Bauer, Walter, Braga, Fernão Castro, Kreis, Wolfgang

“…[Display omitted] •Reaction mechanism of Digitalis lanata 3KSI is investigated.•Isoprogesterone isomerization proceeds via an intramolecular proton…”
Get full text

Development of a bone-targeted pH-sensitive liposomal formulation containing doxorubicin: physicochemical characterization, cytotoxicity, and biodistribution evaluation in a mouse model of bone metastasis by Ferreira, Diêgo Dos Santos, Faria, Samilla Dornelas, Lopes, Sávia Caldeira de Araújo, Teixeira, Cláudia Salviano, Malachias, Angelo, Magalhães-Paniago, Rogério, de Souza Filho, José Dias, Oliveira, Bruno Luis de Jesus Pinto, Guimarães, Alexander Ramos, Caravan, Peter, Ferreira, Lucas Antônio Miranda, Alves, Ricardo José, Oliveira, Mônica Cristina

“…Despite recent advances in cancer therapy, the treatment of bone tumors remains a major challenge. A possible underlying hypothesis, limitation, and unmet need…”
Get full text

Nematicidal activity of Annona crassiflora leaf extract on Caenorhabditis elegans by Machado, Alan Rodrigues Teixeira, Ferreira, Sebastião Rodrigo, da Silva Medeiros, Felipe, Fujiwara, Ricardo Toshio, de Souza Filho, José Dias, Pimenta, Lúcia Pinheiro Santos

“…BACKGROUND: The aim of this work was to investigate the potential nematicidal activity of Annona crassiflora leaf extract against Caenorhabditis elegans…”
Get full text

In Vitro Evaluation of the Activity of Aromatic Nitrocompounds against Trypanosoma cruzi by Oliveira, Renata B, Passos, Ana Paula F, Alves, Rosana O, Romanha, Alvaro J, Prado, Maria Auxiliadora F, de Souza Filho, José Dias, Alves, Ricardo J

“…Fourteen compounds were evaluated for their activity against Trypanosoma cruzi blood stream forms at the concentration of 500 µg/ml. Six compounds were active…”
Get full text

Antimicrobial, antiviral and cytotoxic activity of extracts and constituents from Polygonum spectabile Mart by Brandão, Geraldo Célio, Kroon, Erna Gessien, Duarte, Maria Gorette R., Braga, Fernão Castro, de Souza Filho, José Dias, de Oliveira, Alaíde Braga

“…Polygonum spectabile is used in Brazil for treatment of several infection diseases. Extracts and constituents isolated from this species were evaluated for…”
Get full text

Quantitative analysis of trigonelline in some Annona species by proton NMR spectroscopy by Machado, Alan Rodrigues Teixeira, Lage, Gisele Avelar, Medeiros, Felipe da Silva, de Souza Filho, José Dias, Pimenta, Lúcia Pinheiro Santos

“…A quantitative ¹H NMR method (qHNMR) was used to measure the trigonelline content in the leaves of six species of the Annona genus. The methodology employed…”
Get full text

Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: Anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents by de Souza, Maíra Ribeiro, de Paula, Carmen Aparecida, Pereira de Resende, Michelle Luciane, Grabe-Guimarães, Andrea, de Souza Filho, José Dias, Saúde-Guimarães, Dênia Antunes

“…The ethanolic extract of Lychnophora trichocarpha Spreng. is used in Brazilian folk medicine to treat bruise, pain and inflammatory diseases. The present study…”
Get full text

Síntese de aliloxi-orto-iodobenzamida derivada de d-glicose e reação de ciclização radicalar mediada por hidreto de tri-n-butilestanho by Dias, Danielle Ferreira, Prado, Maria Auxiliadôra Fontes, Pinto, Gleydson Daniel, Alves, Ricardo José, Alves, Rosemeire Brondi, Souza Filho, José Dias de

Get full text