Search Results - "Souza, T. M. de"
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Molecular Modeling Studies of the Structural, Electronic, and UV Absorption Properties of Benzophenone Derivatives
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (15-11-2012)“…Benzophenone derivatives (BZP), an important class of organic UV filters, are widely used in sunscreen products due to their ability to absorb in the UVA and…”
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Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives
Published in Bioorganic & medicinal chemistry (15-12-2006)“…Tuberculosis (TB) is caused by Mycobacterium tuberculosis and remains as a leading cause of mortality worldwide. The in vitro anti-tuberculosis screening of…”
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Somatic homozygous loss of SH2B3, and a non-Robertsonian translocation t(15;21)(q25.3;q22.1) with NTRK3 rearrangement, in an adolescent with progenitor B-cell acute lymphoblastic leukemia with the iAMP21
Published in Cancer genetics (01-04-2022)“…•Pediatric iAMP21-ALL with somatic non-Rob(15;21), NTRK3 rearrangement, and SH2B3 loss.•Sporadic iAMP21 leukemogenesis through chromothripsis and…”
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Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth
Published in Journal of natural products (Washington, D.C.) (26-10-2018)“…The new pyrrole-imidazole and pyrrole-guanidine alkaloids 4-debromooroidin (1), 4-debromougibohlin (2), 5-debromougibohlin (3), and 5-bromopalau’amine (4),…”
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Motivation to Learn Chemistry: A Thorough Analysis of the CMQ-II within the Brazilian Context
Published in Chemistry Education Research and Practice (26-09-2022)“…Studies on students' motivation to learn Chemistry in developed countries are largely common in the literature. However, very few studies have been carried out…”
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249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients
Published in BMC cancer (26-06-2009)“…Ser-249 TP53 mutation (249(Ser)) is a molecular evidence for aflatoxin-related carcinogenesis in Hepatocellular Carcinoma (HCC) and it is frequent in some…”
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Trypanosoma cruzi: Insights into naphthoquinone effects on growth and proteinase activity
Published in Experimental parasitology (2011)“…► Naphthoquinones derivatives decrease in vitro growth Trypanosoma cruzi. ► Cytotoxic activities of these compounds on mammalian VERO cells are dose-dependent…”
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Molecular docking studies of marine diterpenes as inhibitors of wild-type and mutants HIV-1 reverse transcriptase
Published in Marine drugs (29-10-2013)“…AIDS is a pandemic responsible for more than 35 million deaths. The emergence of resistant mutations due to drug use is the biggest cause of treatment failure…”
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Cry2A toxins from Bacillus thuringiensis expressed in insect cells are toxic to two lepidopteran insects
Published in World journal of microbiology & biotechnology (01-12-2008)“…The cry2Aa and cry2Ab genes from a Brazilian Bacillus thuringiensis strain were introduced into the genome of the baculovirus Autographa californica multiple…”
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Abundance and phenology drive plant–pollinator network responses to restoration in the Southern Atlantic rainforest in Brazil
Published in Restoration ecology (01-07-2022)“…Ecological restoration has been increasingly considering biotic interactions. Different restoration strategies usually rely on different composition and…”
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Hantavirus pulmonary syndrome, central plateau, southeastern, and southern Brazil
Published in Emerging infectious diseases (01-04-2009)“…Hantavirus pulmonary syndrome (HPS) is an increasing health problem in Brazil because of encroachment of sprawling urban, agricultural, and cattle-raising…”
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Let's shed light on photogenotoxicity
Published in The Science of the total environment (01-12-2024)“…Photosensitization reactions caused by ultraviolet and visible radiation (UV–vis) absorbing chemicals can induce DNA damage through direct and indirect…”
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Phylogenetic diversity of aerobic spore-forming Bacillalles isolated from Brazilian soils
Published in International microbiology (01-12-2019)“…The phylum Firmicutes comprises seven classes where most species are either aerobic or anaerobic endospore former. Inside Firmicutes , species allocated in the…”
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Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series
Published in Bioorganic & medicinal chemistry (01-01-2007)“…The development of new drugs against Trypanosoma cruzi is still required since the only two drugs currently used cause severe side effects. In this work we…”
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Synthesis and anticancer activities of some novel 2-(benzo[d]thiazol-2-yl)-8-substituted-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones
Published in European journal of medicinal chemistry (01-04-2011)“…A series of 2-(benzo[d]thiazol-2-yl)-8-substituted-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones (3a-g) have been synthesized and evaluated for their in vitro…”
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Fish contamination and human exposure to mercury in the Tapajos River Basin, Para State, Amazon, Brazil: a screening approach
Published in Bulletin of environmental contamination and toxicology (01-08-1997)“…Mercury concentrations were determined in 238 fish specimens from 15 species (9 carnivorous and 6 non-carnivorous) in the Tapajos river, Brazil. The mean…”
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Copper Ions Adsorption from Aqueous Medium Using the Biosorbent Sugarcane Bagasse In Natura and Chemically Modified
Published in Water, air, and soil pollution (01-03-2011)“…This study evaluated the copper ion adsorption capacity of sugarcane bagasse in natura and chemically modified with citric acid and sodium hydroxide…”
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Combining prospect theory and fuzzy numbers to multi-criteria decision making
Published in Expert systems with applications (01-10-2012)“…► Many problems in decision making are affected by risk and uncertainty. ► A novel method based on prospect theory and fuzzy numbers has been proposed to solve…”
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Use of in silico and in vitro methods as a potential new approach methodologies (NAMs) for (photo)mutagenicity and phototoxicity risk assessment of agrochemicals
Published in The Science of the total environment (15-12-2023)“…The increased use of agrochemicals raises concerns about environmental, animal, and mainly human toxicology. The development of New Approach Methodologies…”
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