Search Results - "Souza, T A C B"

Crystal structure of Jararacussin-I: the highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes by Ullah, A, Souza, T A C B, Zanphorlin, L M, Mariutti, R B, Santana, V S, Murakami, M T, Arni, R K

“…Snake venom serine proteinases (SVSPs) are hemostatically active toxins that perturb the maintenance and regulation of both the blood coagulation cascade and…”
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Cloning, Overexpression, Purification and Preliminary Characterization of Human Septin 8 by Souza, T. A. C. B., Barbosa, J. A. R. G.

“…Mammalian septins comprise a family of 14 genes that encode GTP-binding proteins involved in important cellular processes such as cytokinesis and exocytosis…”
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The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure by Campos, I. T. N., Souza, T. A. C. B., Torquato, R. J. S., De Marco, R., Tanaka-Azevedo, A. M., Tanaka, A. S., Barbosa, J. A. R. G.

“…Blood coagulation is an important process in haemostasis, and disorders of blood coagulation can lead to an increased risk of haemorrhage and thrombosis…”
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The role of the quaternary structure in the activation of human L-asparaginase by Morais, S.B., Pirolla, R.A.S., Frota, N.F., Lourenzoni, M.R., Gozzo, F.C., Souza, T.A.C.B.

“…Human L-asparaginase-like protein 1 (ASRGL1) has hydrolytic activity against L-asparagine and isoaspartyl dipeptides. As an N-terminal nucleophile hydrolase…”
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Structural insights into selectivity and cofactor binding in snake venom l-amino acid oxidases by Ullah, A., Souza, T.A.C.B., Abrego, J.R.B., Betzel, C., Murakami, M.T., Arni, R.K.

“…► BjsuLAAO has catalytic preference for hydrophobic residues. ► Active-site volume is determinant for BjsuLAAO specificity. ► The adenosyl moiety adopts a new…”
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In vitro, in vivo and in silico analysis of the anticancer and estrogen-like activity of guava leaf extracts by Rizzo, L Y, Longato, G B, Ruiz, A Lt G, Tinti, S V, Possenti, A, Vendramini-Costa, D B, Sartoratto, A, Figueira, G M, Silva, F L N, Eberlin, M N, Souza, T A C B, Murakami, M T, Rizzo, E, Foglio, M A, Kiessling, F, Lammers, T, Carvalho, J E

“…Anticancer drug research based on natural compounds enabled the discovery of many drugs currently used in cancer therapy. Here, we report the in vitro, in vivo…”
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Crystallographic portrayal of different conformational states of a Lys49 phospholipase A2 homologue: Insights into structural determinants for myotoxicity and dimeric configuration by Ullah, A., Souza, T.A.C.B., Betzel, C., Murakami, M.T., Arni, R.K.

“…► Active site-like region undergoes conformational changes upon ligand binding. ► Lys49 residue participates in ligand interaction. ► Extended dimer is the…”
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