Search Results - "Souza, Robson"
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Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics
Published in Biology direct (25-06-2012)“…Proteinaceous toxins are observed across all levels of inter-organismal and intra-genomic conflicts. These include recently discovered prokaryotic polymorphic…”
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The renin-angiotensin system: going beyond the classical paradigms
Published in American journal of physiology. Heart and circulatory physiology (01-05-2019)“…Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled by the discovery of angiotensin-(1-7) [ANG-(1-7)] generation in vivo. Later,…”
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The ACE2/Angiotensin-(1-7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1-7)
Published in Physiological reviews (01-01-2018)“…The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular system and hydroelectrolyte balance, with an influence on organs and…”
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The World of Cyclic Dinucleotides in Bacterial Behavior
Published in Molecules (Basel, Switzerland) (25-05-2020)“…The regulation of multiple bacterial phenotypes was found to depend on different cyclic dinucleotides (CDNs) that constitute intracellular signaling second…”
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Alamandine acts via MrgD to induce AMPK/NO activation against ANG II hypertrophy in cardiomyocytes
Published in American Journal of Physiology: Cell Physiology (01-06-2018)“…The renin-angiotensin system (RAS) plays a pivotal role in the pathogenesis of cardiovascular diseases. New members of this system have been characterized and…”
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Using climate reanalysis and remote sensing-derived data to create the basis for predicting the occurrence of algal blooms, harmful algal blooms and toxic events in Santa Catarina, Brazil
Published in The Science of the total environment (01-07-2023)“…This study aimed to form a basis for future predictive modeling efforts in support of the harmful algal blooms (HAB) surveillance program currently in force in…”
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ACE2 in the renin-angiotensin system
Published in Clinical science (1979) (11-12-2020)“…In 2020 we are celebrating the 20th anniversary of the angiotensin-converting enzyme 2 (ACE2) discovery. This event was a landmark that shaped the way that we…”
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Population survey of Holothuria (Halodeima) grisea (Aspidochirotida: Holothuriidae) at its limit of geographic distribution in the Western South Atlantic
Published in Revista de biología tropical (01-03-2024)“…Introduction: The sea cucumber Holothuria (Halodeima) grisea Selenka, 1867 is a common echinoderm in intertidal regions along the Brazilian coast, which…”
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Profile of T and B lymphocytes in individuals resistant to Schistosoma mansoni infection
Published in Parasitology research (1987) (01-03-2022)“…The mechanisms involved in the development of resistance to infection/reinfection by Schistosoma mansoni still arouse great interest and controversy. Some…”
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Genomic study of Acinetobacter baumannii strains co-harboring blaOXA-58 and blaNDM-1 reveals a large multidrug-resistant plasmid encoding these carbapenemases in Brazil
Published in Frontiers in microbiology (17-07-2024)“…IntroductionAcinetobacter baumannii contributes significantly to the global issue of multidrug-resistant (MDR) nosocomial infections. Often, these strains…”
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Profiling the rainbow trout hepatic miRNAome under diet-induced hyperglycemia
Published in Physiological genomics (01-09-2019)“…Carnivorous rainbow trout exhibit prolonged postprandial hyperglycemia when fed a diet exceeding 20% carbohydrate content. This poor capacity to utilize…”
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A Family of T6SS Antibacterial Effectors Related to l,d-Transpeptidases Targets the Peptidoglycan
Published in Cell reports (Cambridge) (23-06-2020)“…Type VI secretion systems (T6SSs) are nanomachines used by bacteria to inject toxic effectors into competitors. The identity and mechanism of many effectors…”
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New Components of the Renin-Angiotensin System: Alamandine and the Mas-Related G Protein-Coupled Receptor D
Published in Current hypertension reports (01-06-2014)“…The renin-angiotensin system is an important component of the central and humoral mechanisms of blood pressure and hydro-electrolytic balance control…”
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Water temperature modulation to prevent the South American rock mussel (Perna perna) from spawning during depuration
Published in Ocean and Coastal Research (Online) (2024)“…ABSTRACT Sewage pollution is an increasing problem for Perna perna mussel farmers in Brazil, and there is an urgent need to adopt post-harvest treatments, such…”
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Polyvalent Proteins, a Pervasive Theme in the Intergenomic Biological Conflicts of Bacteriophages and Conjugative Elements
Published in Journal of bacteriology (01-08-2017)“…Intense biological conflicts between prokaryotic genomes and their genomic parasites have resulted in an arms race in terms of the molecular "weaponry"…”
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Update of the global distribution of human gammaherpesvirus 8 genotypes
Published in Scientific reports (07-04-2021)“…Human gammaherpesvirus 8 (HHV-8) consists of six major clades (A–F) based on the genetic sequence of the open reading frame (ORF)-K1. There are a few…”
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Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system
Published in Gene (15-04-2011)“…Though the heterotrimeric G-proteins signaling system is one of the best studied in eukaryotes, its provenance and its prevalence outside of model eukaryotes…”
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ACE2 Knockout Mice Are Resistant to High-Fat Diet-Induced Obesity in an Age-Dependent Manner
Published in International journal of molecular sciences (01-09-2024)“…Angiotensin converting enzyme 2 (ACE2) presents pleiotropic actions. It hydrolyzes angiotensin I (AngI) and angiotensin II (AngII) into angiotensin-(1-9)…”
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Global Distribution and Evolution of Mycobacterium bovis Lineages
Published in Frontiers in microbiology (07-05-2020)“…Mycobacterium bovis is the main causative agent of zoonotic tuberculosis in humans and frequently devastates livestock and wildlife worldwide. Previous studies…”
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Whole genome sequencing of a ST2594 MRSA strain causing non-mucosal preoperative colonization and low-grade postoperative infection
Published in Antonie van Leeuwenhoek (01-06-2019)“…We present a post-operative infection caused by a methicillin-resistant Staphylococcus aureus strain, previously isolated in the preoperative screening, in a…”
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