Search Results - "Souza, Pilar"

Refine Results
  1. 1

    alpha-N-heterocyclic thiosemicarbazone derivatives as potential antitumor agents: a structure-activity relationships approach by Matesanz, Ana I, Souza, Pilar

    Published in Mini reviews in medicinal chemistry (01-10-2009)
    “…alpha-N-Heterocyclic thiosemicarbazones, (N)-TSCs, are potent inhibitors of ribonucleotide reductase (RR). This enzyme plays a critical role in DNA synthesis…”
    Get more information
    Journal Article
  2. 2
  3. 3

    Thiosemicarbazone-Pt(II) Complex Causes a Growth Inhibitory Effect on Human Mesenchymal Stem Cells by Garcia-Ruiz, Josefa Predestinacion, Matesanz Garcia, Ana Isabel, Souza, Ana Perez, Castelo, Pilar Souza

    “…We showed di[3,5-diacetyl-1,2,4-triazolbis(4-cyclohexylthiosemicarbazonato) platinum(II)] complex, (W8), endowed with important antitumor properties. Here, we…”
    Get more information
    Journal Article
  4. 4

    Synthesis and characterization of novel palladium(II) complexes of bis(thiosemicarbazone). Structure, cytotoxic activity and DNA binding of Pd(II)-benzyl bis(thiosemicarbazonate) by Matesanz, Ana I., Pérez, José M., Navarro, Paloma, Moreno, José M., Colacio, Enrique, Souza, Pilar

    Published in Journal of inorganic biochemistry (30-07-1999)
    “…The preparation of palladium(II) complexes of 3,5-diacyl-1,2,4-triazole bis(thiosemicarbazone) (H 2L 2), 2,6-diacylpyridine bis(thiosemicarbazone) (H 2L 3) and…”
    Get full text
    Journal Article
  5. 5
  6. 6
  7. 7

    Palladium(II) and platinum(II) bis(thiosemicarbazone) complexes of the 2,6-diacetylpyridine series with high cytotoxic activity in cisplatin resistant A2780cisR tumor cells and reduced toxicity by Matesanz, Ana I., Leitao, Inés, Souza, Pilar

    Published in Journal of inorganic biochemistry (01-08-2013)
    “…Preparation and characterization of four novel 2,6-diacetylpyridine bis(4N-tolylthiosemicarbazonato) palladium(II) and platinum(II) complexes, [PdL1–2] and…”
    Get full text
    Journal Article
  8. 8
  9. 9

    First 3,5-diacetyl-1,2,4-triazol derived mono(thiosemicarbazone) and its palladium and platinum complexes: Synthesis, structure and biological properties by Matesanz, Ana I., Tapia, Sandra, Souza, Pilar

    Published in Inorganica Chimica Acta (24-04-2016)
    “…The first mono(thiosemicarbazone) ligand based on 3,5-diacetyl-1,2,4-triazol and its Pd(II) and Pt(II) derivatives have been synthesized and characterized. The…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Unprecedented Pt(II) complex of an asymmetric 2,6-diacetylpyridine bis(4N-substituted thiosemicarbazone) ligand by Matesanz, Ana I., Souza, Pilar

    Published in Inorganic chemistry communications (01-01-2013)
    “…Reaction of 2,6-diacetylpyridine bis(4N-o-tolylthiosemicarbazone), H2L1, with K2PtCl4 and further recrystallization in DMSO/MeOH of the [PtL1] complex…”
    Get full text
    Journal Article
  12. 12

    3,5-Diacetyl-1,2,4-triazol bis( 4N-substituted thiosemicarbazone) palladium(II) complexes: Synthesis, structure, antiproliferative activity and low toxicity on normal kidney cells by Matesanz, Ana I., Hernández, Carolina, Rodríguez, Ana, Souza, Pilar

    Published in Journal of inorganic biochemistry (01-12-2011)
    “…Treatment of 4 N-monosubstituted bis(thiosemicarbazone) ligands of 3,5-diacetyl-1,2,4-triazol series with lithium tetrachloridopalladate gave the dinuclear…”
    Get full text
    Journal Article
  13. 13

    New bioactive 2,6-diacetylpyridine bis(p-chlorophenylthiosemicarbazone) ligand and its Pd(II) and Pt(II) complexes: Synthesis, characterization, cytotoxic activity and DNA binding ability by Matesanz, Ana I., Hernández, Carolina, Souza, Pilar

    Published in Journal of inorganic biochemistry (01-09-2014)
    “…Preparation and characterization of 2,6-diacetylpyridine bis(4N-p-chlorophenylthiosemicarbazone) ligand, H2L, and its palladium(II) and platinum(II) complexes…”
    Get full text
    Journal Article
  14. 14

    A new organometallic palladium(II) compound derived of 2,6-diacetylpyridine mono(thiosemicarbazone): Synthesis, spectroscopic properties and crystal structure of two solvatomorphic forms by Matesanz, Ana I., Hernández, Carolina, Souza, Pilar

    Published in Journal of organometallic chemistry (01-02-2014)
    “…Preparation and characterization of a novel 2,6-diacetylpyridine mono(4-methoxyphenyl-thiosemicarbazone), H2L, is described. Treatment of H2L with PdCl2(PPh3)2…”
    Get full text
    Journal Article
  15. 15
  16. 16

    Synthesis and crystal structure of a novel ruthenium(II) complex with in situ generated dithiobiurea ligand by Matesanz, Ana I., Hernández, Carolina, Perles, Josefina, Souza, Pilar

    Published in Journal of organometallic chemistry (15-02-2016)
    “…Upon reaction with RuCl2(PPh3)3 in toluene in presence of triethylamine, 2,6-diacetylpyridine mono(4-methoxyphenyl thiosemicarbazone) undergoes an unusual and…”
    Get full text
    Journal Article
  17. 17
  18. 18

    Novel cyclopalladated and coordination palladium and platinum complexes derived from alpha-diphenyl ethanedione bis(thiosemicarbazones): structural studies and cytotoxic activity against human A2780 and A2780cisR carcinoma cell lines by Matesanz, Ana I, Souza, Pilar

    Published in Journal of inorganic biochemistry (01-10-2007)
    “…The preparation of new palladium(II) and platinum(II) complexes derived from alpha-diphenyl ethanedione bis(thiosemicarbazone), 1, and alpha-diphenyl…”
    Get full text
    Journal Article
  19. 19
  20. 20

    Palladium and platinum 3,5-diacetyl-1,2,4-triazol bis(thiosemicarbazones): Chemistry, cytotoxic activity and structure–activity relationships by Matesanz, Ana I., Souza, Pilar

    Published in Journal of inorganic biochemistry (01-02-2007)
    “…The preparation of platinum(II) complexes derived from 3,5-diacetyl-1,2,4-triazol bis(4-phenylthiosemicarbazone) (H 5L 1), 3,5-diacetyl-1,2,4-triazol…”
    Get full text
    Journal Article