Search Results - "Souza, Marcellus H"

Irinotecan- and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives by Ribeiro, Ronaldo A., Wanderley, Carlos W. S., Wong, Deysi V. T., Mota, José Maurício S. C., Leite, Caio A. V. G., Souza, Marcellus H. L. P., Cunha, Fernando Q., Lima-Júnior, Roberto C. P.

“…Purpose Intestinal mucositis and diarrhea are common manifestations of anticancer regimens that include irinotecan, 5-fluorouracil (5-FU), and other cytotoxic…”
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Regulatory role of Lactobacillus acidophilus on inflammation and gastric dysmotility in intestinal mucositis induced by 5-fluorouracil in mice by Justino, Priscilla F. C., Melo, Luis F. M., Nogueira, Andre F., Morais, Cecila M., Mendes, Walber O., Franco, Alvaro X., Souza, Emmanuel P., Ribeiro, Ronaldo A., Souza, Marcellus H. L. P., Soares, Pedro Marcos Gomes

“…Purpose Lactobacillus acidophilus is widely used for gastrointestinal disorders, but its role in inflammatory conditions like in chemotherapy-induced mucositis…”
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Treatment with Saccharomyces boulardii reduces the inflammation and dysfunction of the gastrointestinal tract in 5-fluorouracil-induced intestinal mucositis in mice by Justino, Priscilla F. C., Melo, Luis F. M., Nogueira, Andre F., Costa, Jose V. G., Silva, Luara M. N., Santos, Cecila M., Mendes, Walber O., Costa, Marina R., Franco, Alvaro X., Lima, Aldo A., Ribeiro, Ronaldo A., Souza, Marcellus H. L. P., Soares, Pedro M. G.

“…Intestinal mucositis is an important toxic side effect of 5-fluorouracil (5-FU) treatment. Saccharomyces boulardii is known to protect from intestinal injury…”
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Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution by Soares, Pedro M. G., Mota, José Maurício S. C., Gomes, Antoniella S., Oliveira, Ricardo B., Assreuy, Ana Maria S., Brito, Gerly Anne C., Santos, Armênio A., Ribeiro, Ronaldo A., Souza, Marcellus H. L. P.

“…Aim To evaluate gastrointestinal motility during 5-fluorouracil (5-FU)-induced intestinal mucositis. Materials and methods Wistar rats received 5-FU (150 mg kg…”
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Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation by Lima-Júnior, Roberto César P., Figueiredo, Aline A., Freitas, Helano C., Melo, Maria Luisa P., Wong, Deysi Viviana T., Leite, Caio Abner V. G., Medeiros, Raul P., Marques-Neto, Raphael D., Vale, Mariana L., Brito, Gerly Anne C., Oriá, Reinaldo B., Souza, Marcellus H. L. P., Cunha, Fernando Q., Ribeiro, Ronaldo A.

“…Purpose Intestinal mucositis and the closely associated diarrhea are common costly side effects of irinotecan. Cytokine modulators, such as thalidomide and…”
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Role of cytokines (TNF-α, IL-1β and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide by Melo, Maria Luisa P., Brito, Gerly A. C., Soares, Rudy C., Carvalho, Sarah B. L. M., Silva, Johan V., Soares, Pedro M. G., Vale, Mariana L., Souza, Marcellus H. L. P., Cunha, Fernando Q., Ribeiro, Ronaldo A.

“…Introduction Irinotecan (CPT-11) is an inhibitor of DNA topoisomerase I and is clinically effective against several cancers. A major toxic effect of CPT-11 is…”
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Neuropathy and primary headaches affect different subgroups of inflammatory bowel disease patients by Leitão, Antônio M. F., Ribeiro Junior, Howard L., Araújo, Davi F., Braga, Lúcia L. B. C., Souza, Marcellus H. L. P., Barbosa, Alzira M. C., Viana Júnior, Antônio B., Gondim, Francisco De A. A.

“…Background Peripheral neuropathies (PN) and primary headaches (PH) are common comorbidities in inflammatory bowel disease (IBD) patients. We aimed to evaluate…”
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Gabapentin, a Synthetic Analogue of Gamma Aminobutyric Acid, Reverses Systemic Acute Inflammation and Oxidative Stress in Mice by Dias, Jordana Maia, de Brito, Tarcisio Vieira, de Aguiar Magalhães, Diva, da Silva Santos, Pammela Weryka, Batista, Jalles Arruda, do Nascimento Dias, Eulina Gabriela, de Barros Fernandes, Heliana, Damasceno, Samara Rodrigues Bonfim, Silva, Renan O., Aragão, Karoline S., Souza, Marcellus H. L. P., Medeiros, Jand-Venes R., Barbosa, André Luiz R.

“…The aim of this study was to investigate the potential anti-inflammatory and anti-oxidant effects of gabapentin (GBP) in mice. The anti-inflammatory and…”
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Polysaccharides isolated from Digenea simplex inhibit inflammatory and nociceptive responses by Pereira, Juliana G., Mesquita, Jacilane X., Aragão, Karoline S., Franco, Álvaro X., Souza, Marcellus H.L.P., Brito, Tarcisio V., Dias, Jordana M., Silva, Renan O., Medeiros, Jand-Venes R., Oliveira, Jefferson S., Abreu, Clara Myrla W.S., de Paula, Regina Célia M., Barbosa, André Luiz R., Freitas, Ana Lúcia P.

“…•Polysaccharides (PLS) significantly reduced the inflammatory response induced by several mediators.•PLS reduced the neutrophil migration and decreased the…”
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Efficacy of a phenol derivative, isopropyl vanillate, as an anti‐inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration by Nogueira, Kerolayne M., Souza, Luan K. M., Oliveira, Ana P., Pacheco, Gabriella, Iles, Bruno, Alencar, Matheus S., Nicolau, Lucas A. D., Silva, Renan O., Nóbrega, Flávio R., Sousa, Damião P., Souza, Marcellus H. L. P., Medeiros, Jand V. R.

“…Inflammation is the response of the body to noxious stimuli such as infections, trauma, or injury. Experimental studies have shown that vanillic acid has…”
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Gastroprotective effect of heme-oxygenase 1/biliverdin/CO pathway in ethanol-induced gastric damage in mice by Gomes, Antoniella S., Gadelha, Gemima G., Lima, Samara J., Garcia, Joyce A., Medeiros, Jand Venes R., Havt, Alexandre, Lima, Aldo A., Ribeiro, Ronaldo A., Brito, Gerly Anne C., Cunha, Fernando Q., Souza, Marcellus H.L.P.

“…Our objective was to evaluate the role of heme-oxygenase 1 (HO-1)/biliverdin/CO pathway in gastric defense against ethanol-induced gastric damage in mice. Mice…”
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Anal canal anatomy showed by three-dimensional anorectal ultrasonography by SERGIO, F, REGADAS, P, MURAD-REGADAS, Sthela M, LIMA, Doryane M. R, SILVA, Flavio R, BARRETO, Rosilma G. L, SOUZA, Marcellus H. L. P, REGADAS FILHO, P

“…Demonstrate precisely the anatomic configuration of the anal canal and the length and thickness of the anal sphincters using three-dimensional (3-D) anorectal…”
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Religious coping and its influence on psychological distress, medication adherence, and quality of life in inflammatory bowel disease by Freitas, Thiago H, Hyphantis, Thomas N, Andreoulakis, Elias, Quevedo, João, Miranda, Hesley L, Alves, Gilberto S, Souza, Marcellus H, Braga, Lúcia L, Pargament, Kenneth I, Soczynska, Joanna K, McIntyre, Roger S, Carvalho, André F

“…Inflammatory bowel disease (IBD) is associated with elevated levels of anxiety and depression and a reduction in health-related quality of life (HRQoL)…”
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Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice by Soares, Pedro M. G., Lima-Junior, Roberto C. P., Mota, José Maurício S. C., Justino, Priscilla F. C., Brito, Gerly Anne C., Ribeiro, Ronaldo A., Cunha, Fernando Q., Souza, Marcellus H. L. P.

“…Purpose Gastrointestinal mucositis is a common side effect of cancer chemotherapy. Platelet-activating factor (PAF) is produced during gut inflammation. There…”
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Laryngeal Mucosa Alterations in Mice Model of Gastroesophageal Reflux: Effects of Topical Protection by Figueiredo, Aline A., Sales, Thiago M. A. L., Nicolau, Lucas A. D., Nunes, André A. A., Costa‐Filho, Humberto B., Moreira, Rhubens L. R., Nascimento, Renata R., Sousa, Maria K. A., Silva, Lorena D., Carmo‐Neto, João P., Sidou, Flávio M. N. O., Paula, Suliana M., Medeiros, Jand V. R., Silva, Durcilene A., Sifrim, Daniel, Souza, Marcellus H. L. P.

“…Objectives/Hypothesis The objectives of this study were to evaluate laryngeal inflammation and mucosal integrity in a murine model of reflux disease and to…”
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Riparin B, a Synthetic Compound Analogue of Riparin, Inhibits the Systemic Inflammatory Response and Oxidative Stress in Mice by Santiago, Renata Fortes, de Brito, Tarcisio Vieira, Dias, Jordana Maia, Dias, Genilson José, da Cruz, José Simião, Batista, Jalles Arruda, Silva, Renan Oliveira, Souza, Marcellus H. L. P., de Albuquerque Ribeiro, Ronaldo, Gutierrez, Stanley Juan Chavez, Freitas, Rivelilson M., Medeiros, Jand-Venes R., dos Reis Barbosa, André Luiz

“…The aim of our study was to evaluate the anti-inflammatory, anti-nociceptive, and anti-oxidant action of Riparin B in vivo . We performed experiments in which…”
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Biopolymer Extracted from Anadenanthera colubrina (Red Angico Gum) Exerts Therapeutic Potential in Mice: Antidiarrheal Activity and Safety Assessment by Araújo, Thiago S L, de Oliveira, Taiane M, de Sousa, Nayara A, Souza, Luan K M, Sousa, Francisca B M, de Oliveira, Ana P, Nicolau, Lucas A D, da Silva, Alfredo A V, Araújo, Alyne R, Magalhães, Pedro J C, Vasconcelos, Daniel F P, de Jonge, Hugo R, Souza, Marcellus H L P, Silva, Durcilene A, Paula, Regina C M, Medeiros, Jand Venes R

“…var. cebil (Griseb.) Altschul (Fabaceae family), commonly known as the red angico tree, is a medicinal plant found throughout Brazil's semi-arid area. In this…”
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Topical protection of mice laryngeal mucosa using the natural product cashew gum by Figueiredo, Aline A., Santana, Ana P. M., Nicolau, Lucas A. D., Batista‐Lima, Francisco J., Wong, Deysi V. T., Lucetti, Larisse T., Batista, Gabriela L. P., Caminha, Natália A., Medeiros, Jand V. R., Silva, Durcilene A., Leite, José R. S. A., Santos, Armênio A., Soares, Pedro M. G., Sifrim, Daniel, Souza, Marcellus H. L. P.

“…Objectives/Hypothesis Evaluate the effect of in vitro exposure of mice laryngeal mucosa to solutions that simulated human gastric juice and to assess the…”
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Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons by Medeiros, Jand Venes R, Bezerra, Víctor H, Gomes, Antoniella S, Barbosa, André Luiz R, Lima-Júnior, Roberto César P, Soares, Pedro Marcos G, Brito, Gerly Anne C, Ribeiro, Ronaldo A, Cunha, Fernando Q, Souza, Marcellus H L P

“…The aim of this study was to evaluate the protective effect of hydrogen sulfide (H(2)S) on ethanol-induced gastric lesions in mice and the influence of…”
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Role of Capsaicin-Sensitive Primary Afferent Neurons and Non-protein Sulphydryl Groups on Gastroprotective Effect of Amifostine Against Ethanol-Induced Gastric Damage in Rats by Junqueira-Júnior, Jerônimo, Junqueira, Ana Flávia Torquato Araújo, Medeiros, Jand Venes R, Barbosa, Sergio Henrique Brito, Nogueira, Ana Carolina Pereira, Mota, José Maurício Segundo Correia, Santana, Ana Paula Macêdo, Brito, Gerly Anne C, Ribeiro, Ronaldo A, Lima-Júnior, Roberto César P, Souza, Marcellus H. L. P

“…Background Amifostine has been widely tested as a cytoprotective agent against a number of aggressors in different organs. Recently, a gastroprotective effect…”
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