Search Results - "Souza, Laura L."
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MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells
Published in Molecular and cellular biochemistry (01-04-2017)“…Cisplatin is a drug widely used in chemotherapy that frequently causes severe renal dysfunction. Organic transporters have an important role to control the…”
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Hemopressin is an inverse agonist of CB₁ cannabinoid receptors
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2007)“…To date, the endogenous ligands described for cannabinoid receptors have been derived from membrane lipids. To identify a peptide ligand for CB₁ cannabinoid…”
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3
Inhibition of Autophagy Enhances the Antitumor Effect of Thioridazine in Acute Lymphoblastic Leukemia Cells
Published in Life (Basel, Switzerland) (20-04-2021)“…Acute lymphoblastic leukemia (ALL) is an aggressive malignant disorder of lymphoid progenitor cells that affects children and adults. Despite the high cure…”
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Rosemary ( Rosmarinus officinalis L.) Glycolic Extract Protects Liver Mitochondria from Oxidative Damage and Prevents Acetaminophen-Induced Hepatotoxicity
Published in Antioxidants (01-03-2023)“…L. (rosemary) is an aromatic culinary herb. Native to the Mediterranean region, it is currently cultivated worldwide. In addition to its use as a condiment in…”
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Angiotensin-(1-7) decreases LPS-induced inflammatory response in macrophages
Published in Journal of cellular physiology (01-05-2012)“…It has been previously shown that besides its classical role in blood pressure control the renin–angiotensin system, mainly by action of angiotensin II on the…”
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Receptor Mas Protects Mice Against Hypothermia and Mortality Induced By Endotoxemia
Published in Shock (Augusta, Ga.) (01-04-2014)“…ABSTRACTThe renin-angiotensin (Ang) system is involved in maintaining cardiovascular function by regulating blood pressure and electrolyte homeostasis. More…”
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Angiotensin II–Independent Angiotensin-(1–7) Formation in Rat Hippocampus: Involvement of Thimet Oligopeptidase
Published in Hypertension (Dallas, Tex. 1979) (01-11-2013)“…The involvement and relevance of the renin–angiotensin system have been established clearly in cardiovascular diseases, and renin–angiotensin system…”
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Mas receptor deficiency exacerbates lipopolysaccharide-induced cerebral and systemic inflammation in mice
Published in Immunobiology (1979) (01-12-2015)“…Abstract Beyond the classical actions of the renin-angiotensin system on the regulation of cardiovascular homeostasis, several studies have shown its…”
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Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes
Published in Molecular and cellular endocrinology (01-07-2024)“…Maternal diabetes may influence glucose metabolism in adult offspring, an area with limited research on underlying mechanisms. Our study explored the impact of…”
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Carboxypeptidases A1 and A2 from the perfusate of rat mesenteric arterial bed differentially process angiotensin peptides
Published in Peptides (New York, N.Y. : 1980) (01-01-2012)“…► Rat vascular CPA1 and CPA2 are novel angiotensin-processing enzymes. ► Rat CPA1 metabolizes Ang II to Ang-(1-7). ► Rat CPA2 catalyzes a stepwise conversion…”
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Angiotensin processing is partially carried out by carboxypeptidases in the rat mesenteric arterial bed perfusate
Published in Regulatory peptides (29-11-2008)“…Here we investigated the possible association between the carboxypeptidase A (CPA)-like activity of the rat mesenteric arterial bed (MAB) perfusate and the…”
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Carboxypeptidase B and other kininases of the rat coronary and mesenteric arterial bed perfusates
Published in American journal of physiology. Heart and circulatory physiology (01-12-2007)“…We describe the enzymes that constitute the major bradykinin (BK)-processing pathways in the perfusates of mesenteric arterial bed (MAB) and coronary vessels…”
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Hemopressin is an inverse agonist of CB^sub 1^ cannabinoid receptors
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2007)“…To date, the endogenous ligands described for cannabinoid receptors have been derived from membrane lipids. To identify a peptide ligand for CB^sub 1^…”
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14
Hemopressin is an inverse agonist of CB 1 cannabinoid receptors
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2007)“…To date, the endogenous ligands described for cannabinoid receptors have been derived from membrane lipids. To identify a peptide ligand for CB 1 cannabinoid…”
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