Search Results - "Souza, Helivaldo"
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1
Nonlinear Refraction, Excited State Absorption, and Multiphoton Absorption of 1,3-Thiazolium-5-thiolate Mesoionic Compound
Published in The journal of physical chemistry. B (10-08-2023)“…We synthesized the mesoionic compound 2-(4-chlorophenyl)-3-methyl-4-(4-methylphenyl)-1,3-thiazole-5-thiolate and measured its refractive and absorptive…”
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2
Terpinen-4-ol as an Antibacterial and Antibiofilm Agent against Staphylococcus aureus
Published in International journal of molecular sciences (25-06-2020)“…is able to rapidly develop mechanisms of resistance to various drugs and to form strong biofilms, which makes it necessary to develop new antibacterial drugs…”
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3
First Hyperpolarizability of 1,3‑Thiazolium-5-Thiolates Mesoionic Compounds
Published in Journal of physical chemistry. C (10-01-2019)“…The first hyperpolarizabilities of the mesoionic compounds (MICs) 2-(4-chlorophenyl)-3-methyl-4-phenyl-1,3-thiazolium-5-thiolate (MIC-1),…”
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4
Novel esters derived from 4-hydroxychalcones as potential sunscreens with antimicrobial action
Published in Synthetic communications (17-06-2024)“…Ten novel 4-esterchalcones, licochalcone analogues, were strategically synthesized to study the effect of electro-donating or electro-withdrawing substituents…”
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5
Antifungal activity of 2‐chloro‐N‐phenylacetamide, docking and molecular dynamics studies against clinical isolates of Candida tropicalis and Candida parapsilosis
Published in Journal of applied microbiology (01-05-2022)“…Aims This study evaluated the antifungal, antibiofilm and molecular docking of 2‐chloro‐N‐phenylacetamide against clinical isolates of Candida tropicalis and…”
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6
Antibacterial and Antibiofilm Activity of Myrtenol against Staphylococcus aureus
Published in Pharmaceuticals (Basel, Switzerland) (25-06-2020)“…The increase in Staphylococcus aureus resistance to conventional antibacterials and persistent infections related to biofilms, as well as the low availability…”
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7
Effect of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide in combination with antibacterial drugs against Klebsiella pneumoniae
Published in Anais da Academia Brasileira de Ciências (01-01-2023)“…Klebsiella pneumoniae is a species of Gram-negative bacteria related to a wide range of infections and high rates of drug resistance. The combined use of…”
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8
Antifungal activity and mechanism of action of 2-chloro-N -phenylacetamide: a new molecule with activity against strains of Aspergillus flavus
Published in Anais da Academia Brasileira de Ciências (01-01-2021)“…Abstract Aspergillus genus causes many diseases, and the species Aspergillus flavus is highly virulent. Treatment of aspergillosis involves azole derivatives…”
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9
Synthesis, in silico Study and Antileishmanial Evaluation of New Selenides Derived from 7-Chloro-quinoline and N-Phenylacetamides
Published in Journal of the Brazilian Chemical Society (01-04-2021)“…This study describes a virtual screening performed for two series of selenides (28 compounds), derived from N-phenylacetamides chlorides and…”
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10
Combined structure- and ligand-based virtual screening aiding discovery of selenoglycolicamides as potential multitarget agents against Leishmania species
Published in Journal of molecular structure (15-12-2019)“…Leishmaniasis is a neglected disease that does not have adequate treatment. We created a database with 30 selenoglycolicamides and evaluated their potential…”
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11
Synthesis, Spectroscopic Characterization, DFT Calculations and Preliminary Antifungal Activity of New Piperine Derivatives
Published in Journal of the Brazilian Chemical Society (01-03-2021)“…Four new piperine derivatives, PC1-PC4, were synthesized, and their structures were fully characterized by infrared (IR) and 1H and 13C nuclear magnetic…”
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12
New Diesters Derived from Piperine: in silico Study and Evaluation of Their Antimicrobial Potential
Published in Journal of the Brazilian Chemical Society (01-08-2020)“…Piperine, previously extracted from black pepper (Piper nigrum L.), was used as a precursor for the synthesis of twelve new diester derivatives. The final…”
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13
Potential of 2-Chloro- N -(4-fluoro-3-nitrophenyl)acetamide Against Klebsiella pneumoniae and In Vitro Toxicity Analysis
Published in Molecules (Basel, Switzerland) (31-08-2020)“…causes a wide range of community and nosocomial infections. The high capacity of this pathogen to acquire resistance drugs makes it necessary to develop…”
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14
Synthesis, in silico Study and Antimicrobial Evaluation of New Selenoglycolicamides
Published in Journal of the Brazilian Chemical Society (01-01-2019)“…Nine new compounds derived from selenoglycolic acid were synthesized, and their structures were fully characterized by elemental analysis, infrared (IR), 1H…”
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15
(R)-(+)-β-Citronellol and (S)-(-)-β-Citronellol in Combination with Amphotericin B against Candida Spp
Published in International journal of molecular sciences (05-03-2020)“…The enantiomers (R)-(+)-β-citronellol and (S)-(-)-β-citronellol are present in many medicinal plants, but little is understood about their bioactivity against…”
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16
Synthesis, in silico Study, Theoretical Stereochemistry Elucidation and Antifungal Activity of New Imides Derived from Safrole
Published in Journal of the Brazilian Chemical Society (01-10-2020)“…Ten imides derived from safrole, 4a-4j, were synthesized and their structures were fully characterized by infrared (IR) spectroscopy, 1H and 13C nuclear…”
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17
Mechanistic studies of cytotoxic activity of the mesoionic compound MIH 2.4Bl in MCF‑7 breast cancer cells
Published in Oncology letters (01-09-2020)“…In the present study, the cytotoxic effects of a 1,3-thiazolium-5-thiolate derivative of a mesoionic compound, MIH 2.4Bl, were assessed in the MCF-7 breast…”
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18
The impact that β-citronellol isomers have on the biofilm formation of Candida yeasts
Published in Natural product research (17-12-2021)“…Infections associated with biofilms developed by spp. are becoming a great problem due to its resistance against the immune response of the host and the action…”
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19
Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro-N-phenylacetamide
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-03-2024)“…Aspergillus niger causes infections such as otitis and pulmonary aspergillosis in immunocompromised individuals. Treatment involves voriconazole or…”
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20
Synthesis, in silico Study and Antimicrobial Evaluation of New Diesters Derived from Phthaloylglycine
Published in Journal of the Brazilian Chemical Society (01-05-2020)“…New diesters derived from phthaloylglycine (7a-7i) were synthesized and their structures characterized by infrared, 1H and 13C nuclear magnetic resonance (NMR)…”
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