Search Results - "Souza, Gustavo H. M. F."
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Expression of functional recombinant human growth hormone in transgenic soybean seeds
Published in Transgenic research (01-08-2011)“…We produced human growth hormone (hGH), a protein that stimulates growth and cell reproduction, in genetically engineered soybean [ Glycine max (L.) Merrill]…”
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2
Accumulation of functional recombinant human coagulation factor IX in transgenic soybean seeds
Published in Transgenic research (01-08-2011)“…The seed-based production of recombinant proteins is an efficient strategy to achieve the accumulation, correct folding, and increased stability of these…”
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3
Ion Mobility‐Enhanced Data‐Independent Acquisitions Enable a Deep Proteomic Landscape of Oligodendrocytes
Published in Proteomics (Weinheim) (01-11-2017)“…Oligodendrocytes are a type of neuroglia that provide trophic support and insulation to axons in the central nervous system. The genesis and maturation of…”
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Label-free quantitative proteomics of Corynebacterium pseudotuberculosis isolates reveals differences between Biovars ovis and equi strains
Published in BMC genomics (08-06-2017)“…Background Corynebacterium pseudotuberculosis is a pathogen classified into two biovars: C. pseudotuberculosis biovar ovis, the etiologic agent of caseous…”
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Label-free MSE proteomic analysis of chronic myeloid leukemia bone marrow plasma: disclosing new insights from therapy resistance
Published in Proteomics (Weinheim) (01-08-2012)“…Chronic myeloid leukemia (CML) is a pluripotent hematopoietic disorder that is currently considered incurable. The tyrosine kinase product of the Philadelphia…”
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Investigating the Potential of Ion Mobility-Mass Spectrometry for Microalgae Biomass Characterization
Published in Analytical chemistry (Washington) (16-07-2019)“…Algae biomass is formed by an extremely complex set of metabolites, and its molecular characterization has been very challenging. We report the…”
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Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia
Published in Journal of psychiatric research (01-07-2009)“…Abstract Schizophrenia is likely to be a consequence of serial alterations in a number of genes that, together with environmental factors, will lead to the…”
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A shift in the virulence potential of Corynebacterium pseudotuberculosis biovar ovis after passage in a murine host demonstrated through comparative proteomics
Published in BMC microbiology (22-03-2017)“…Corynebacterium pseudotuberculosis biovar ovis, a facultative intracellular pathogen, is the etiologic agent of caseous lymphadenitis in small ruminants…”
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Detection and expression analysis of recombinant proteins in plant‐derived complex mixtures using nanoUPLC‐MSE
Published in Journal of separation science (01-10-2011)“…The use of mass spectrometry to identify recombinant proteins that are expressed in total soluble proteins (TSPs) from plant extracts is necessary to…”
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A sportomics soccer investigation unveils an exercise-induced shift in tyrosine metabolism leading to hawkinsinuria
Published in Frontiers in nutrition (Lausanne) (13-06-2023)“…Tyrosine metabolism has an intense role in the synthesis of neurotransmitters. Our study used an untargeted, sportomics-based analysis of urine samples to…”
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Secretome of the preimplantation human embryo by bottom-up label-free proteomics
Published in Analytical and bioanalytical chemistry (01-09-2011)“…A bottom-up label-free mass spectrometric proteomic strategy was used to analyse the protein profiles of the human embryonic secretome. Culture media samples…”
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12
Purification and characterization of a keratinolytic metalloprotease from Chryseobacterium sp. kr6
Published in Journal of biotechnology (20-02-2007)“…The Chryseobacterium sp. kr6 strain has been described as a highly keratinolytic bacterium showing effective feather-degrading and de-hairing activities. A…”
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Differential Metabolism of a Two-Carbon Substrate by Members of the Paracoccidioides Genus
Published in Frontiers in microbiology (27-11-2017)“…The genus comprises known fungal pathogens of humans and can be isolated from different infection sites. Metabolic peculiarities in different members of the…”
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Quantitative Proteomic Analysis Reveals Changes in the Benchmark Corynebacterium pseudotuberculosis Biovar Equi Exoproteome after Passage in a Murine Host
Published in Frontiers in cellular and infection microbiology (25-07-2017)“…biovar is the etiologic agent of ulcerative lymphangitis. To investigate proteins that could be related to the virulence of this pathogen, we combined an…”
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Diacerhein downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice
Published in International immunopharmacology (01-06-2008)“…NOD mice are used as experimental models as they develop type 1 diabetes mellitus (DM-1) spontaneously, with a strong similarity to the human disease. Diabetes…”
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Intrinsic Mobility of Gaseous Cationic and Anionic Aggregates of Ionic Liquids
Published in Chemphyschem (06-06-2011)“…Travelling‐wave ion mobility mass spectrometry was used to measure the intrinsic mobility of a series of gaseous supra‐cation and supra‐anion aggregates of…”
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Peptide fingerprinting of snake venoms by direct infusion nano-electrospray ionization mass spectrometry: potential use in venom identification and taxonomy
Published in Journal of mass spectrometry. (01-05-2008)“…Fingerprinting by mass spectrometry has been increasingly used to study venom variations and for taxonomic analyses based on venom components. Most of these…”
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ESI-MS/MS identification of a bradykinin-potentiating peptide from Amazon Bothrops atrox snake venom using a hybrid Qq-oaTOF mass spectrometer
Published in Toxins (18-02-2013)“…A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m/z 1384.7386 was identified and characterized by collision induced dissociation…”
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Longissimus dorsi muscle label-free quantitative proteomic reveals biological mechanisms associated with intramuscular fat deposition
Published in Journal of proteomics (15-05-2018)“…The pathways involved in intramuscular fat (IMF) deposition in Longissimus dorsi muscle were investigated using an integrated transcriptome-assisted label-free…”
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Characterization of the mechanisms underlying the inflammatory response to Polistes lanio lanio (paper wasp) venom in mouse dorsal skin
Published in Toxicon (Oxford) (2009)“…Stings by Polistes wasps can cause life-threatening allergic reactions, pain and inflammation. We examined the changes in microvascular permeability and…”
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