Search Results - "Souza, Gloria EP"
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The antipyretic effect of dipyrone is unrelated to inhibition of PGE2 synthesis in the hypothalamus
Published in British journal of pharmacology (01-03-2011)“…BACKGROUND AND PURPOSE Bacterial lipopolysaccharide (LPS) induces fever through two parallel pathways; one, prostaglandin (PG)‐dependent and the other,…”
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2
Cyclooxygenase-derived mediators regulate the immunological control of Strongyloides venezuelensis infection
Published in FEMS immunology and medical microbiology (01-06-2010)“…The aim of this study was to define the immunoregulatory role of prostaglandins in a mouse model of Strongyloides venezuelensis infection. Strongyloides…”
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3
Lipopolysaccharide-Induced Sickness Behaviour Evaluated in Different Models of Anxiety and Innate Fear in Rats
Published in Basic & clinical pharmacology & toxicology (01-04-2012)“…: The fact that there is a complex and bidirectional communication between the immune and nervous systems has been well demonstrated. Lipopolysaccharide…”
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4
Cytokines, but not corticotropin-releasing factor and endothelin-1, participate centrally in the febrile response in zymosan-induced arthritis in rats
Published in Brain research (12-06-2015)“…Abstract Recent literature has revealed that centrally generated prostaglandins participate in the febrile response in zymosan-induced arthritis in rats…”
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5
Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators
Published in Brain, behavior, and immunity (01-01-2016)“…Highlights • Endocannabinoids participate in the fever induced by TNF, IL-1β, IL-6, CRF and ET-1. • Endocannabinoids are not involved in the fever induced by…”
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6
A crucial role for IL-6 in the CNS of rats during fever induced by the injection of live E. coli
Published in Medical microbiology and immunology (01-02-2012)“…Interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and IL-6 have been established as important mediators of fever induced by lipopolysaccharide (LPS) from…”
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7
Endogenous opioids: role in prostaglandin-dependent and -independent fever
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-02-2008)“…This study evaluated the participation of mu-opioid-receptor activation in body temperature (T(b)) during normal and febrile conditions (including activation…”
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8
Mediators involved in the febrile response induced by Tityus serrulatus scorpion venom in rats
Published in Toxicon (Oxford) (01-10-2006)“…Tityus serrulatus venom (Tsv) was intraperitoneally (ip) injected at doses of 75, 150 and 300 μg/kg and IL-1 β (2.0 μg/kg) was given intravenously (iv) to male…”
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9
Febrile response induced by cecal ligation and puncture (CLP) in rats: involvement of prostaglandin E sub(2) and cytokines
Published in Medical microbiology and immunology (01-05-2012)“…The purpose of the present study was to better understand the events involved in the febrile response induced by cecal ligation and puncture (CLP), a complex…”
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10
Interleukin-1 mediates endothelin-1-induced fever and prostaglandin production in the preoptic area of rats
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-06-2006)“…The intracerebroventricular injection of endothelin-1 (ET-1) induces fever and increases PG levels in the cerebrospinal fluid of rats. Likewise, the injection…”
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11
The antipyretic effect of dipyrone is unrelated to inhibition of PGE 2 synthesis in the hypothalamus
Published in British journal of pharmacology (01-03-2011)“…BACKGROUND AND PURPOSE Bacterial lipopolysaccharide (LPS) induces fever through two parallel pathways; one, prostaglandin (PG)‐dependent and the other,…”
Get full text
Journal Article -
12
Simultaneous determination of dipyrone metabolites in rat hypothalamus, cerebrospinal fluid and plasma samples by LC-MS/MS
Published in Bioanalysis (01-11-2013)“…After oral administration dipyrone is rapidly hydrolyzed to 4-methylaminoantipyrine, which is absorbed and further metabolized to 4-formylaminoantipyrine and…”
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