Search Results - "Souza, Gabriela F. P."
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Catalytic redox-neutral C-H functionalisation with TEMPO in water to access aminomethyl-substituted pyrroles
Published in Organic & biomolecular chemistry (04-05-2022)“…A redox-neutral C-H functionalisation in water employing catalytic TEMPO to synthesize aminomethyl-substituted pyrroles is reported. Starting from cheap and…”
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2
Visible-Light-Driven Epoxyacylation and Hydroacylation of Olefins Using Methylene Blue/Persulfate System in Water
Published in Journal of organic chemistry (03-08-2018)“…A visible-light-driven strategy for hydroacylation and epoxyacylation of olefins in water using methylene blue as photoredox catalyst and persulfate as oxidant…”
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3
The pathophysiology of defective proteostasis in the hypothalamus — from obesity to ageing
Published in Nature reviews. Endocrinology (01-12-2016)“…Key Points Specialized neurons of the hypothalamus control caloric intake and energy expenditure in response to hormonal, nutritional and neural signals that…”
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S-nitroso-N-acetylcysteine attenuates liver fibrosis in cirrhotic rats
Published in Journal of molecular medicine (Berlin, Germany) (01-04-2010)“…This study was aimed to investigate the molecular mechanisms underlying prevention of hepatic fibrosis by S-nitroso-N-acetylcysteine (SNAC), a nitric oxide…”
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Detection and Analysis of Florfenicol Residues and Metabolites in Nile Tilapia (Oreochromis niloticus) Tissues Post-Oral Administration in Tropical Waters
Published in Journal of veterinary pharmacology and therapeutics (27-09-2024)“…Water temperature is a critical environmental parameter that significantly influences fish metabolism. This study assessed the metabolism of florfenicol (FF)…”
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Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity
Published in Scientific reports (04-07-2016)“…Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the…”
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n-3 Fatty Acids Induce Neurogenesis of Predominantly POMC-Expressing Cells in the Hypothalamus
Published in Diabetes (New York, N.Y.) (01-03-2016)“…Apoptosis of hypothalamic neurons is believed to play an important role in the development and perpetuation of obesity. Similar to the hippocampus, the…”
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“On Water” Metal-Catalyst-Free Oxidative Coupling–Amidation of Amines To Access Imines and Amides
Published in ACS sustainable chemistry & engineering (05-09-2017)“…A simple route toward the selective synthesis of imines and amides through oxidative coupling–oxidative amidation of amines using widely available NaOCl is…”
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S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis
Published in Drug design, development and therapy (01-01-2013)“…S-Nitroso-N-acetylcysteine (SNAC) is a water soluble primary S-nitrosothiol capable of transferring and releasing nitric oxide and inducing several biochemical…”
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Nitric oxide released from luminal s-nitroso-N-acetylcysteine increases gastric mucosal blood flow
Published in Molecules (Basel, Switzerland) (04-03-2015)“…Nitric oxide (NO)-mediated vasodilation plays a key role in gastric mucosal defense, and NO-donor drugs may protect against diseases associated with gastric…”
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Antithrombogenic Polynitrosated Polyester/Poly(methyl methacrylate) Blend for the Coating of Blood-Contacting Surfaces
Published in Artificial organs (01-04-2008)“…: A nitric oxide (NO) donor polyester containing multiple S‐nitrosothiol (S‐NO) groups covalently attached to the polymer backbone was synthesized through the…”
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(-)-Tarchonanthuslactone exerts a blood glucose-increasing effect in experimental type 2 diabetes mellitus
Published in Molecules (Basel, Switzerland) (19-03-2015)“…A number of studies have proposed an anti-diabetic effect for tarchonanthuslactone based on its structural similarity with caffeic acid, a compound known for…”
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S-nitrosoglutathione inhibits inducible nitric oxide synthase upregulation by redox posttranslational modification in experimental diabetic retinopathy
Published in Investigative ophthalmology & visual science (02-05-2014)“…Diabetic retinopathy (DR) is associated with nitrosative stress. The purpose of this study was to evaluate the beneficial effects of S-nitrosoglutathione…”
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In vitro inhibition of linoleic acid peroxidation by primary S-nitrosothiols
Published in Journal of the Brazilian Chemical Society (2010)“…Nitric oxide (•NO) is an effective chain-breaking antioxidant in the inhibition of lipid peroxidation and circulates in vivo mainly as primary S-nitrosothiols…”
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A metal-catalyst-free oxidative coupling of anilines to aromatic azo compounds in water using bleach
Published in Tetrahedron letters (17-10-2018)“…[Display omitted] •Synthesis of symmetrical and unsymmetrical aromatic azo compounds from anilines using a straightforward protocol in water.•Low-cost reagents…”
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