Search Results - "Souza, Flávio Falcão Lima"
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Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL‐induced osteoclastogenesis
Published in British journal of pharmacology (01-02-2024)“…Background and Purpose Rheumatoid arthritis (RA) is a chronic autoimmune disease that can cause bone erosion due to increased osteoclastogenesis. Neutrophils…”
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Neutrophil extracellular traps mediate joint hyperalgesia induced by immune inflammation
Published in Rheumatology (Oxford, England) (01-07-2021)“…Abstract Objective To evaluate the role of neutrophil extracellular traps (NETs) in the genesis of joint hyperalgesia using an experimental model of arthritis…”
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Systemic Lupus Erythematosus Activity Affects the Sinusoidal Uptake Transporter OATP1B1 Evaluated by the Pharmacokinetics of Atorvastatin
Published in Clinical and translational science (01-11-2020)“…The present study assessed the effect of systemic lupus erythematosus (SLE) activity, a chronic and inflammatory autoimmune disease, on the sinusoidal uptake…”
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Are neutrophil extracellular traps the link for the cross-talk between periodontitis and rheumatoid arthritis physiopathology?
Published in Rheumatology (Oxford, England) (24-12-2021)“…Abstract Objectives Neutrophil extracellular traps (NETs) play a role in the pathogenesis of periodontitis and rheumatoid arthritis (RA). However, it remains…”
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Synovial fluid survivin and NETs as independent biomarkers in rheumatoid arthritis
Published in Clinical and experimental rheumatology (01-07-2023)“…To quantify survivin and NETs in synovial fluid (SF) of patients with rheumatoid arthritis (RA) and osteoarthritis (OA), and to assess whether there is a…”
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Rheumatoid arthritis downregulates the drug transporter OATP1B1: Fluvastatin as a probe
Published in European journal of pharmaceutical sciences (15-04-2020)“…•RA associated with elevated levels of IL-6 and TNF-α downregulates CYP enzymes.•Fluvastatin is a substrate of OATP1B1 and it is metabolized by…”
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