Search Results - "Souza, Daniel Menezes"
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Leishmania LiHyC protein is immunogenic and induces protection against visceral leishmaniasis
Published in Parasite immunology (01-08-2022)“…Treatment against visceral leishmaniasis (VL) presents problems by the toxicity of drugs, high cost and/or emergence of resistant strains. The diagnosis is…”
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New antigens for the serological diagnosis of human visceral leishmaniasis identified by immunogenomic screening
Published in PloS one (20-12-2018)“…Visceral leishmaniasis (VL) still represents a serious public health problem in Brazil due to the inefficiency of the control measures currently employed, that…”
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A burocratização da ressocialização: uma análise das concepções de educadores atuantes no sistema de privação de liberdade
Published in Revista Principia (03-03-2020)“…This study presents a qualitative research of a case study conducted with 5 socioeducators from Funase, Abreu e Lima - PE. These professionals were chosen…”
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4
Chimeric Protein Designed by Genome-Scale Immunoinformatics Enhances Serodiagnosis of Bovine Neosporosis
Published in Journal of clinical microbiology (24-06-2020)“…Neosporosis has become a concern since it is associated with abortion in cattle. Currently, diagnosis is determined through anamnesis, evaluation of the…”
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Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-07-2016)“…Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide. Although chemotherapy has been widely used to treat this disease,…”
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In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection
Published in Biomedicine & pharmacotherapy (01-01-2019)“…[Display omitted] •A naphthoquinone derivate, Flau-A, was tested against Leishmania infection.•It was incorporated into a Poloxamer 407-containing polymeric…”
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7
Treatment of murine visceral leishmaniasis using an 8-hydroxyquinoline-containing polymeric micelle system
Published in Parasitology international (01-12-2016)“…Abstract New therapeutics are urgently needed to treat visceral leishmaniasis (VL). Due to the fact that drug discovery is a long and expensive process, the…”
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Mimotope-based vaccines of Leishmania infantum antigens and their protective efficacy against visceral leishmaniasis
Published in PloS one (15-10-2014)“…The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display…”
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Mapping B-cell epitopes for the peroxidoxin of Leishmania (Viannia) braziliensis and its potential for the clinical diagnosis of tegumentary and visceral leishmaniasis
Published in PloS one (12-06-2014)“…The search toward the establishment of novel serological tests for the diagnosis of leishmaniasis and proper differential diagnosis may represent one…”
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Leishmania infantum β-Tubulin Identified by Reverse Engineering Technology through Phage Display Applied as Theranostic Marker for Human Visceral Leishmaniasis
Published in International journal of molecular sciences (12-04-2019)“…Two mimotopes (B10 and C01) identified by phage display showed to be antigenic and immunogenic for visceral (VL) and tegumentary (TL) leishmaniasis; however,…”
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Parasitological and immunological evaluation of a novel chemotherapeutic agent against visceral leishmaniasis
Published in Parasite immunology (01-12-2020)“…Aims Treatment for visceral leishmaniasis (VL) is hampered by the toxicity and/or high cost of drugs, as well as by emergence of parasite resistance…”
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12
An ELISA immunoassay employing a conserved Leishmania hypothetical protein for the serodiagnosis of visceral and tegumentary leishmaniasis in dogs and humans
Published in Cellular immunology (01-08-2017)“…[Display omitted] •Antigens used in the serodiagnosis of leishmaniasis present problems.•A conserved Leishmania hypothetical protein was identified.•It was…”
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13
A clioquinol-containing Pluronic ® F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model
Published in Parasite (Paris) (2020)“…A clioquinol (ICHQ)-containing Pluronic F127 polymeric micelle system (ICHQ/Mic) was recently shown to be effective against Leishmania amazonensis infection in…”
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Serological diagnosis and prognostic of tegumentary and visceral leishmaniasis using a conserved Leishmania hypothetical protein
Published in Parasitology international (01-06-2018)“…New candidates for serological markers against leishmaniasis are required to be identified, since the presence of high titers of anti-Leishmania antibodies…”
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15
Evaluation of a hypothetical protein for serodiagnosis and as a potential marker for post-treatment serological evaluation of tegumentary leishmaniasis patients
Published in Parasitology research (1987) (01-04-2017)“…The serodiagnosis for tegumentary leishmaniasis (TL) presents problems related to the sensitivity and/or specificity of the tests. In the present study, an…”
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Improving serodiagnosis of human and canine leishmaniasis with recombinant Leishmania braziliensis cathepsin l-like protein and a synthetic peptide containing its linear B-cell epitope
Published in PLoS neglected tropical diseases (01-01-2015)“…The early and correct diagnosis of human leishmaniasis is essential for disease treatment. Another important step in the control of visceral leishmaniasis is…”
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Cytokine and transcription factor profiles in the skin of dogs naturally infected by Leishmania (Leishmania) chagasi presenting distinct cutaneous parasite density and clinical status
Published in Veterinary parasitology (19-04-2011)“…The immune response in the skin of dogs infected with Leishmania chagasi and its association with distinct levels of tissue parasitism and clinical progression…”
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Identification of differentially expressed proteins from Leishmania amazonensis associated with the loss of virulence of the parasites
Published in PLoS neglected tropical diseases (01-04-2014)“…The present study analyzed whether or not the in vitro cultivation for long periods of time of pre-isolated Leishmania amazonensis from lesions of chronically…”
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Canine skin and conjunctival swab samples for the detection and quantification of Leishmania infantum DNA in an endemic urban area in Brazil
Published in PLoS neglected tropical diseases (01-04-2012)“…We evaluated kDNA PCR/hybridization and quantitative real-time PCR (qPCR) targeting the gene of DNA polymerase of Leishmania infantum for CVL diagnosis and…”
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A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as a vaccine candidate against, visceral leishmaniasis
Published in Parasites & vectors (11-07-2015)“…LiHyV is an antigenic hypothetical protein present in both promastigote and amastigote stages of Leishmania infantum, which was recently identified by an…”
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