Search Results - "Souza, Ana Camila Oliveira"
-
1
Trichophyton rubrum is inhibited by free and nanoparticle encapsulated curcumin by induction of nitrosative stress after photodynamic activation
Published in PloS one (24-03-2015)“…Antimicrobial photodynamic inhibition (aPI) utilizes radical stress generated from the excitation of a photosensitizer (PS) with light to destroy pathogens…”
Get full text
Journal Article -
2
New Role of P. brasiliensis α-Glucan: Differentiation of Non-conventional Dendritic Cells
Published in Frontiers in microbiology (30-10-2019)“…The cell wall has a critical role in the host immune response to fungal pathogens. In this study, we investigated the influence of two cell wall fractions of…”
Get full text
Journal Article -
3
Antifungal Activity of Amphotericin B Conjugated to Nanosized Magnetite in the Treatment of Paracoccidioidomycosis
Published in PLoS neglected tropical diseases (15-06-2016)“…This study reports on in vitro and in vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising…”
Get full text
Journal Article -
4
Whole-genome sequencing reveals highly specific gene targeting by in vitro assembled Cas9-ribonucleoprotein complexes in Aspergillus fumigatus
Published in Fungal biology and biotechnology (05-06-2018)“…CRISPR/Cas9-based genome editing is quickly becoming a powerful tool within the field of fungal genetics. Adaptation of CRISPR/Cas9 systems are allowing for…”
Get full text
Journal Article -
5
Intranasal Vaccine Using P10 Peptide Complexed within Chitosan Polymeric Nanoparticles as Experimental Therapy for Paracoccidioidomycosis in Murine Model
Published in Journal of fungi (Basel) (01-09-2020)“…Paracoccidioidomycosis (PCM) is a granulomatous fungal disease caused by the dimorphic fungal species of Paracoccidioides, which mainly affects the lungs…”
Get full text
Journal Article -
6
A conserved fungal morphogenetic kinase regulates pathogenic growth in response to carbon source diversity
Published in Nature communications (17-10-2024)“…Fungal pathogens must exhibit strong nutritional plasticity, effectively sensing and utilizing diverse nutrients to support virulence. How the signals…”
Get full text
Journal Article -
7
Loss of Septation Initiation Network (SIN) kinases blocks tissue invasion and unlocks echinocandin cidal activity against Aspergillus fumigatus
Published in PLoS pathogens (09-08-2021)“…Although considered effective treatment for many yeast fungi, the therapeutic efficacy of the echinocandin class of antifungals for invasive aspergillosis (IA)…”
Get full text
Journal Article -
8
Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans
Published in The Journal of immunology (1950) (01-03-2015)“…Human infection with Cryptococcus neoformans, a common fungal pathogen, follows deposition of yeast spores in the lung alveoli. The subsequent host-pathogen…”
Get full text
Journal Article -
9
SH3‐class Ras guanine nucleotide exchange factors are essential for Aspergillus fumigatus invasive growth
Published in Cellular microbiology (01-06-2019)“…Proper hyphal morphogenesis is essential for the establishment and progression of invasive disease caused by filamentous fungi. In the human pathogen…”
Get full text
Journal Article -
10
C-terminus Proteolysis and Palmitoylation Cooperate for Optimal Plasma Membrane Localization of RasA in Aspergillus fumigatus
Published in Frontiers in microbiology (26-03-2018)“…RasA is a major regulator of fungal morphogenesis and virulence in . The proper localization of RasA to the plasma membrane is essential for the formation of…”
Get full text
Journal Article -
11
Correction: Macrophage Mitochondrial and Stress Response to Ingestion of Cryptococcus neoformans
Published in The Journal of immunology (1950) (01-09-2017)Get full text
Journal Article -
12
β2 Integrin-Mediated Susceptibility to Paracoccidioides brasiliensis Experimental Infection in Mice
Published in Frontiers in cellular and infection microbiology (16-03-2021)“…The earliest interaction between macrophages and is particularly important in paracoccidioidomycosis (PCM) progression, and surface proteins play a central…”
Get full text
Journal Article -
13
Distinct patterns of yeast cell morphology and host responses induced by representative strains of Paracoccidioides brasiliensis (Pb18) and Paracoccidioides lutzii (Pb01)
Published in Medical mycology (Oxford) (01-02-2016)“…Paracoccidioidomycosis (PCM) is a systemic mycosis, widespread in Latin America. PCM is a granulomatous disease characterized by a polymorphism of lesions…”
Get full text
Journal Article -
14
Differential requirements of protein geranylgeranylation for the virulence of human pathogenic fungi
Published in Virulence (01-01-2019)“…Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and…”
Get full text
Journal Article -
15
DNA-hsp65 vaccine as therapeutic strategy to treat experimental chromoblastomycosis caused by Fonsecaea pedrosoi
Published in Mycopathologia (1975) (01-06-2013)“…Chromoblastomycosis (CBM) is a chronic subcutaneous mycosis, caused by several dimorphic, pigmented dematiaceous fungi. Patients with the disease are still…”
Get full text
Journal Article -
16
DNA-hsp65 Vaccine as Therapeutic Strategy to Treat Experimental Chromoblastomycosis Caused by FonsecaeaPedrosoi
Published in Mycopathologia (1975) (01-06-2013)“…Chromoblastomycosis (CBM) is a chronic subcutaneous mycosis, caused by several dimorphic, pigmented dematiaceous fungi. Patients with the disease are still…”
Get full text
Journal Article -
17
Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction
Published in The Journal of infectious diseases (15-07-2016)“…Background. The relevance of antibodies (Abs) in the defense against Mycobacterium tuberculosis infection remains uncertain. We investigated the role of Abs to…”
Get full text
Journal Article -
18
Miconazole loaded chitosan-based nanoparticles for local treatment of vulvovaginal candidiasis fungal infections
Published in Colloids and surfaces, B, Biointerfaces (01-02-2019)“…[Display omitted] •Miconazole nitrate was encapsulated within chitosan nanoparticles.•Average diameter of the nanoparticles ranging from 200 to 300 nm.•The…”
Get full text
Journal Article -
19
Loss of Septation Initiation Network
Published in PLoS pathogens (09-08-2021)Get full text
Journal Article