Search Results - "Souto, J C"

Patient self-management of oral anticoagulation with vitamin K antagonists in everyday practice: clinical outcomes in a single centre cohort after long-term follow-up by Corrochano, M, Jiménez, B, Millón, J, Gich, I, Rambla, M, Gil, E, Caparrós, P, Macho, R, Souto, J C

“…Patient self-management (PSM) of vitamin K antagonists (VKA) seems a very promising model of care for oral anticoagulation in terms of efficacy and safety. In…”
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Risk of a first venous thrombotic event in carriers of a familial thrombophilic defect. The European Prospective Cohort on Thrombophilia (EPCOT) by VOSSEN, C. Y., CONARD, J., FONTCUBERTA, J., MAKRIS, M., VAN DER MEER, F. J. M., PABINGER, I., PALARETI, G., PRESTON, F. E., SCHARRER, I., SOUTO, J. C., SVENSSON, P., WALKER, I. D., ROSENDAAL, F. R.

“…Background: Reliable risk estimates for venous thrombosis in families with inherited thrombophilia are scarce but necessary for determining optimal screening…”
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Risk of ischemic stroke associated with functional thrombin-activatable fibrinolysis inhibitor plasma levels by SANTAMARIA, A, OLIVER, A, BORRELL, M, MATEO, J, BELVIS, R, MARTI-FABREGAS, J, ORTIN, R, TIRADO, I, SOUTO, J. C, FONTCUBERTA, J

“…Recently, a novel procarboxypeptidase B-like proenzyme, called thrombin-activatable fibrinolysis inhibitor (TAFI), has been described. It plays an important…”
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Genetic determinants of plasma β2‐glycoprotein I levels: a genome‐wide association study in extended pedigrees from Spain by Athanasiadis, G., Sabater‐Lleal, M., Buil, A., Souto, J. C., Borrell, M., Lathrop, M., Watkins, H., Almasy, L., Hamsten, A., Soria, J. M.

“…Summary Background β2‐Glycoprotein I (β2‐GPI), also designated apolipoprotein H, is a 50‐kDa protein that circulates in blood at high concentrations, playing…”
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Low-molecular-weight heparin as bridging therapy during interruption of oral anticoagulation in patients undergoing colonoscopy or gastroscopy by Constans, M, Santamaria, A, Mateo, J, Pujol, N, Souto, J C, Fontcuberta, J

“…Nowadays, most patients under oral anticoagulant therapy (OAT) require invasive procedures such as colonoscopy (CC) or gastroscopy (GC). The goals of the…”
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Genetic determinants of hemostasis phenotypes in spanish families by SOUTO, J. C, ALMASY, L, BORRELL, M, GARI, M, MARTINEZ, E, MATEO, J, STONE, W. H, BLANGERO, J, FONTCUBERTA, J

“…Recent studies have described genetic mutations that affect the risk of thrombosis as a result of abnormal levels of such hemostatic parameters as protein C,…”
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Familial thrombophilia and lifetime risk of venous thrombosis by Vossen, C. Y., Conard, J., Fontcuberta, J., Makris, M., Van Der Meer, F. J. M., Pabinger, I., Palareti, G., Preston, F. E., Scharrer, I., Souto, J. C., Svensson, P., Walker, I. D., Rosendaal, F. R.

“…Summary  Background : We started a large multicenter prospective follow‐up study to provide reliable risk estimates of venous thrombosis in families with…”
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Functional Effects of the ABO Locus Polymorphism on Plasma Levels of von Willebrand Factor, Factor VIII, and Activated Partial Thromboplastin Time by Souto, Juan Carlos, Almasy, Laura, Muñiz-Diaz, Eduardo, Soria, José Manuel, Borrell, Montserrat, Bayén, Laia, Mateo, José, Madoz, Pedro, Stone, William, Blangero, John, Fontcuberta, Jordi

“…Lower levels of factor VIII and von Willebrand factor (vWF) have been reported in individuals with blood type O compared with individuals with other ABO blood…”
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Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis by Soria, José Manuel, Almasy, Laura, Souto, Juan Carlos, Tirado, Isabel, Borell, Montserrat, Mateo, José, Slifer, Susan, Stone, William, Blangero, John, Fontcuberta, Jordi

“…Association studies suggest that the G20210A mutation (G to A substitution at nucleotide position 20210) in the prothrombin gene (PT) is associated with…”
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Hereditary thrombophilia and fetal loss: a prospective follow‐up study by Vossen, C. Y., Preston, F. E., Conard, J., Fontcuberta, J., Makris, M., Van Der Meer, F. J. M., Pabinger, I., Palareti, G., Scharrer, I., Souto, J. C., Svensson, P., Walker, I. D., Rosendaal, F. R.

“…Background: As the placental vessels are dependent on the normal balance of procoagulant and anticoagulant mechanisms, inherited thrombophilia may be…”
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A Locus on Chromosome 2 Influences Levels of Tissue Factor Pathway Inhibitor: Results From the GAIT study by Almasy, L, Soria, J M, Souto, J C, Warren, D M, Buil, A, Borrell, M, Muñoz, X, Sala, N, Lathrop, M, Fontcuberta, J, Blangero, J

“…OBJECTIVE—Levels of tissue factor pathway inhibitor (TFPI) have been associated with arteriosclerosis and thrombotic disease. Although a genetic component to…”
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Antitumoral effect of maintained neutrophilia induced by rhG-CSF in a murine model of pancreatic cancer by Brú, A., Bosch, R., Céspedes, M. V., Carmona-Güedes, S., Pascual, E., Brú, I., Souto, J. C.

“…Although the protumoral functions of polymorphonuclear neutrophils are well known, some now-forgotten studies report antitumoral roles for these cells. The…”
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The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population by Souto, J C, Coll, I, Llobet, D, del Río, E, Oliver, A, Mateo, J, Borrell, M, Fontcuberta, J

“…We investigated the prevalence of the new recently reported mutation in the prothrombin gene (20210 A) in a sample of 116 unrelated patients with venous…”
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Low ADAMTS13 levels are associated with venous thrombosis risk in women by Llobet, D., Tirado, I., Vilalta, N., Vallvé, C., Oliver, A., Vázquez-Santiago, M., Mateo, J., Millón, J., Fontcuberta, J., Souto, J.C.

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Genetic studies in complex disease: the case pro linkage studies by Souto, J. C.

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Association between ABO haplotypes and the risk of venous thrombosis: impact on disease risk estimation by Goumidi, Louisa, Thibord, Florian, Wiggins, Kerri L., Li-Gao, Ruifang, Brown, Mickael R., van Hylckama Vlieg, Astrid, Souto, Joan-Carles, Soria, José-Manuel, Ibrahim-Kosta, Manal, Saut, Noémie, Daian, Delphine, Olaso, Robert, Amouyel, Philippe, Debette, Stéphanie, Boland, Anne, Bailly, Pascal, Morrison, Alanna C., Mook-Kanamori, Denis O., Deleuze, Jean-François, Johnson, Andrew, de Vries, Paul S., Sabater-Lleal, Maria, Chiaroni, Jacques, Smith, Nicholas L., Rosendaal, Frits R., Chasman, Daniel I., Trégouët, David-Alexandre, Morange, Pierre-Emmanuel

“…Genetic risk score (GRS) analysis is a popular approach to derive individual risk prediction models for complex diseases. In venous thrombosis (VT), such type…”
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Risk of thrombosis associated with oral contraceptives of women from 97 families with inherited thrombophilia: high risk of thrombosis in carriers of the G20210A mutation of the prothrombin gene by Santamaria, A, Mateo, J, Oliver, A, Menendez, B, Souto, JC, Borrell, M, Soria, JM, Tirado, I, Fontcuberta, J

“…Thrombosis and Haemostasis Unit, Haematology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. BACKGROUND AND OBJECTIVES: Oral contraceptives…”
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Prothrombotic state and signs of endothelial lesion in plasma of patients with inflammatory bowel disease by SOUTO, J. C, MARTINEZ, E, ROCA, M, MATEO, J, PUJOL, J, GONZALEZ, D, FONTCUBERTA, J

“…Recent investigations suggest that microthrombi formation in bowel capillaries could be a determinant factor in inflammatory bowel disease (IBD) pathogenesis…”
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Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study by Olson, N. C., Butenas, S., Lange, L. A., Lange, E. M., Cushman, M., Jenny, N. S., Walston, J., Souto, J. C., Soria, J. M., Chauhan, G., Debette, S., Longstreth, W. T., Seshadri, S., Reiner, A. P., Tracy, R. P.

“…Summary Background The relationships of thrombin generation (TG) with cardiovascular disease risk are underevaluated in population‐based cohorts. Objectives To…”
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Oral surgery in anticoagulated patients without reducing the dose of oral anticoagulant: a prospective randomized study by Souto, J C, Oliver, A, Zuazu-Jausoro, I, Vives, A, Fontcuberta, J

“…This study assessed the risk associated with several schedules of perioperative treatment with coumadin in anticoagulated patients who underwent oral surgery…”
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