Search Results - "Souto, E B"

Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications by Araújo, J., Gonzalez-Mira, E., Egea, M.A., Garcia, M.L., Souto, E.B.

“…The purpose of this study was to develop a novel nanostructured lipid carrier (NLC) for the intravitreal-targeting delivery of triamcinolone acetonide (TA) by…”
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Cosmetic features and applications of lipid nanoparticles (SLN®, NLC®) by Souto, E. B., Müller, R. H.

“…Synopsis A detailed review of the literature is presented in attempts to emphasize several advantages of solid lipid nanoparticles (SLN) and nanostructured…”
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Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery by Souto, E.B, Wissing, S.A, Barbosa, C.M, Müller, R.H

“…Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) are colloidal carrier systems providing controlled release profiles for many…”
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Advances in nanomedicines for malaria treatment by Aditya, N.P., Vathsala, P.G., Vieira, V., Murthy, R.S.R., Souto, E.B.

“…Malaria is an infectious disease that mainly affects children and pregnant women from tropical countries. The mortality rate of people infected with malaria…”
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Tramadol hydrochloride: Pharmacokinetics, pharmacodynamics, adverse side effects, co-administration of drugs and new drug delivery systems by Vazzana, M, Andreani, T, Fangueiro, J, Faggio, C, Silva, C, Santini, A, Garcia, M.L, Silva, A.M, Souto, E.B

“…Abstract Tramadol hydrochloride (TrHC) is a synthetic analgesic drug exhibiting opioid and non-opioid properties, acting mainly on the central nervous system…”
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Oral bioavailability of cyclosporine: Solid lipid nanoparticles (SLN ®) versus drug nanocrystals by Müller, R.H., Runge, S., Ravelli, V., Mehnert, W., Thünemann, A.F., Souto, E.B.

“…For the development of an optimized oral formulation for cyclosporine A, 2% of this drug has been formulated in solid lipid nanoparticles (SLN™, mean size 157…”
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Cyclosporine-loaded solid lipid nanoparticles (SLN ®): Drug–lipid physicochemical interactions and characterization of drug incorporation by Müller, R.H., Runge, S.A., Ravelli, V., Thünemann, A.F., Mehnert, W., Souto, E.B.

“…Solid lipid nanoparticles (SLN) were produced loaded with cyclosporine A in order to develop an improved oral formulation. In this study, the particles were…”
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Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen by González-Mira, E, Nikolić, S, García, M L, Egea, M A, Souto, E B, Calpena, A C

“…The potential use of nanostructured lipid carriers (NLC) composed of a fatty acid [stearic acid (SA)] or a triglyceride (glyceryl behenate) as solid lipids,…”
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Arthemeter-loaded lipid nanoparticles produced by modified thin-film hydration: Pharmacokinetics, toxicological and in vivo anti-malarial activity by Aditya, N.P., Patankar, S., Madhusudhan, B., Murthy, R.S.R., Souto, E.B.

“…Artemether-loaded lipid nanoparticles (ARM-LNP) composed of 5% (w/v) lipid mass were produced by a modified thin-film hydration method using glyceryl…”
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Modified Rose Bengal assay for surface hydrophobicity evaluation of cationic solid lipid nanoparticles (cSLN) by Doktorovova, S., Shegokar, R., Martins-Lopes, P., Silva, A.M., Lopes, C.M., Müller, R.H., Souto, E.B.

“…Surface hydrophobicity of nanocarriers influences protein binding and subsequently fate of nanoparticles in blood circulation. Therefore, characterization of…”
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SLN and NLC for topical delivery of ketoconazole by Souto, E. B., Müller, R. H.

“…The clinical use of ketoconazole has been related to some adverse effects in healthy adults, specially local reactions, such as severe irritation, pruritus and…”
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Investigation of the factors influencing the incorporation of clotrimazole in SLN and NLC prepared by hot high-pressure homogenization by Souto, E. B., Müller, R. H.

“…Clotrimazole, a fungicidal effective for the local treatment of cutaneous and mucosal infections, was incorporated into solid lipid nanoparticles (SLN) and…”
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Beyond liposomes: Recent advances on lipid based nanostructures for poorly soluble/poorly permeable drug delivery by Teixeira, M.C., Carbone, C., Souto, E.B.

“…Solid lipid nanoparticle (SLN), nanostructured lipid carriers (NLC) and hybrid nanoparticles, have gained increasing interest as drug delivery systems because…”
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Nanostructured lipid carriers as novel carrier for sunscreen formulations by Xia, Q., Saupe, A., Müller, R. H., Souto, E. B.

“…Synopsis Incorporation of sunscreens into lipid carriers with an increased sun protection factor (SPF) has not yet been fully accomplished. In the present…”
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Lopinavir loaded solid lipid nanoparticles (SLN) for intestinal lymphatic targeting by Aji Alex, M.R., Chacko, A.J., Jose, S., Souto, E.B.

“…The poor orally available lopinavir was successfully encapsulated in glyceryl behenate based solid lipid nanoparticles (Lo-SLN) for its ultimate use to target…”
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Lipid-based colloidal systems (nanoparticles, microemulsions) for drug delivery to the skin: materials and end-product formulations by Souto, E.B., Doktorovova, S., Boonme, P.

“…Drug delivery to or via the skin presents both unique opportunities and obstacles due to skin structure, physiology, and barrier properties. The skin, the…”
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Preparation and characterization of n-dodecyl-ferulate-loaded solid lipid nanoparticles (SLN ®) by Souto, E.B., Anselmi, C., Centini, M., Müller, R.H.

“…Solid lipid nanoparticles (SLN ™) containing a novel potential sunscreen n-dodecyl-ferulate (ester of ferulic acid) were developed. The preparation and…”
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Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations by Souto, E.B, Wissing, S.A, Barbosa, C.M, Müller, R.H

“…Aqueous dispersions of lipid nanoparticles are being investigated as drug delivery systems for different therapeutic purposes. One of their interesting…”
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Lipid nanoparticles (SLN, NLC): Overcoming the anatomical and physiological barriers of the eye – Part I – Barriers and determining factors in ocular delivery by Sánchez-López, E., Espina, M., Doktorovova, S., Souto, E.B., García, M.L.

“…[Display omitted] Ocular drug delivery is still a challenge for researchers in the field of pharmaceutical technology due to anatomical and physiological eye…”
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A novel approach based on lipid nanoparticles (SLN®) for topical delivery of α-lipoic acid by Souto, E. B., Müller, R. H., Gohla, S.

“…This study describes the development, preparation and characterization of solid lipid nanoparticles (SLN®) containing the novel anti-ageing substance α-lipoic…”
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