Search Results - "Southwood, Taunton"
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Medically Significant Infections Are Increased in Patients With Juvenile Idiopathic Arthritis Treated With Etanercept: Results From the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2015)“…Objective The association between anti–tumor necrosis factor therapy and increased rates of infection is widely documented in adults with rheumatoid arthritis…”
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Successful stopping of biologic therapy for remission in children and young people with juvenile idiopathic arthritis
Published in Rheumatology (Oxford, England) (02-05-2023)“…Abstract Objectives Clinicians concerned about long-term safety of biologics in JIA may consider tapering or stopping treatment once remission is achieved…”
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Factors associated with improvement in disease activity following initiation of etanercept in children and young people with Juvenile Idiopathic Arthritis: results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study
Published in Rheumatology (Oxford, England) (01-05-2016)“…The objectives of this study were to investigate change in disease activity, and explore factors associated with response, in children with JIA over the…”
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Short-term outcomes in patients with systemic juvenile idiopathic arthritis treated with either tocilizumab or anakinra
Published in Rheumatology (Oxford, England) (01-01-2019)“…Abstract Objectives To investigate real-world short-term outcomes among patients with systemic JIA starting tocilizumab or anakinra. Methods This analysis…”
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Paediatric rheumatic disease: Treatment of JIA in the biologic era: what are we waiting for?
Published in Nature reviews. Rheumatology (01-03-2014)Get full text
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Factors associated with choice of biologic among children with Juvenile Idiopathic Arthritis: results from two UK paediatric biologic registers
Published in Rheumatology (Oxford, England) (01-09-2016)“…The objectives of this study were to describe patients starting first-line biologics for JIA, to describe characteristics over time among patients starting…”
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Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins
Published in The Lancet (British edition) (19-10-2002)“…The frequency and ethnic variation of Henoch-Schönlein purpura, Kawasaki disease, and rarer vasculitides during childhood are not well characterised. Our aim…”
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International league of associations for rheumatology classification of juvenile idiopathic arthritis: Second revision, Edmonton, 2001
Published in Journal of rheumatology (01-02-2004)Get full text
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Treatment of JIA in the biologic era: what are we waiting for?
Published in Nature reviews. Rheumatology (01-03-2014)“…If the use of the right treatment at the right time might 'cure' juvenile idiopathic arthritis, how do we determine the optimum timing of biologic therapy? The…”
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Use and effectiveness of rituximab in children and young people with juvenile idiopathic arthritis in a cohort study in the United Kingdom
Published in Rheumatology (Oxford, England) (01-02-2019)“…Abstract Objectives Rituximab (RTX) may be a treatment option for children and young people with JIA, although it is not licensed for this indication. The aim…”
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Growth in children and adolescents with juvenile idiopathic arthritis over 2 years of treatment with etanercept: results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study
Published in Rheumatology (Oxford, England) (01-07-2015)“…Children with JIA can experience delayed and restricted growth. The objectives of this study were to investigate the influence of etanercept (ETN) on vertical…”
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Methotrexate persistence and adverse drug reactions in patients with juvenile idiopathic arthritis
Published in Rheumatology (Oxford, England) (01-08-2019)“…This analysis aims to calculate MTX monotherapy persistence and describe the occurrence of and factors associated with the occurrence of adverse drug reactions…”
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Outcomes after anti-tumour necrosis factor originator to biosimilar switching in children and young people with juvenile idiopathic arthritis in the UK: a national cohort study
Published in The Lancet. Rheumatology (01-07-2024)“…For cost-saving purposes, children and young people with juvenile idiopathic arthritis (JIA) are being switched (for non-medical reasons) from biological…”
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The Association of Intrapair Birth-Weight Differences With Internalizing and Externalizing Behavior Problems
Published in Twin research and human genetics (01-06-2018)“…Problem behaviors are of increasing public health concern. Twin studies have revealed substantial genetic and environmental influences on children's behavior,…”
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Gestational Weight Gain by Maternal Pre-pregnancy BMI and Childhood Problem Behaviours in School-Age Years: A Pooled Analysis of Two European Birth Cohorts
Published in Maternal and child health journal (01-10-2020)“…Objectives Maternal pre-pregnancy weight is known to affect foetal development. However, it has not yet been clarified if gestational weight gain is associated…”
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Maternal pre-pregnancy weight and externalising behaviour problems in preschool children: a UK-based twin study
Published in BMJ open (14-10-2014)“…Objective To estimate the heritability of child behaviour problems and investigate the association between maternal pre-pregnancy overweight and child…”
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Striking intrafamilial phenotypic variability in Aicardi–Goutières syndrome associated with the recurrent Asian founder mutation in RNASEH2C
Published in American journal of medical genetics. Part A (01-02-2013)“…Aicardi–Goutières syndrome (AGS) is an encephalopathy of early childhood which is most commonly inherited as an autosomal recessive trait. The disorder…”
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Duration of etanercept treatment and reasons for discontinuation in a cohort of juvenile idiopathic arthritis patients
Published in Rheumatology (Oxford, England) (01-01-2011)“…Since 2004, juvenile idiopathic arthritis (JIA) patients treated with etanercept and/or MTX have been monitored in the British Society for Paediatric and…”
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An empirical study on the preferred size of the participant information sheet in research
Published in Journal of medical ethics (01-09-2011)“…BackgroundInformed consent is a requirement for all research. It is not, however, clear how much information is sufficient to make an informed decision about…”
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Using registries to identify adverse events in rheumatic diseases
Published in Pediatrics (Evanston) (01-11-2013)“…The proven effectiveness of biologics and other immunomodulatory products in inflammatory rheumatic diseases has resulted in their widespread use as well as…”
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