Search Results - "Southern, D."

TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis by Scheraga, Rachel G, Abraham, Susamma, Niese, Kathryn A, Southern, Brian D, Grove, Lisa M, Hite, R Duncan, McDonald, Christine, Hamilton, Thomas A, Olman, Mitchell A

“…Macrophage phagocytosis of particles and pathogens is an essential aspect of innate host defense. Phagocytic function requires cytoskeletal rearrangements that…”
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TRPV4 Protects the Lung from Bacterial Pneumonia via MAPK Molecular Pathway Switching by Scheraga, Rachel G, Abraham, Susamma, Grove, Lisa M, Southern, Brian D, Crish, James F, Perelas, Apostolos, McDonald, Christine, Asosingh, Kewal, Hasday, Jeffrey D, Olman, Mitchell A

“…Mechanical cell-matrix interactions can drive the innate immune responses to infection; however, the molecular underpinnings of these responses remain elusive…”
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Expert consensus on the management of systemic sclerosis-associated interstitial lung disease by Rahaghi, Franck F, Hsu, Vivien M, Kaner, Robert J, Mayes, Maureen D, Rosas, Ivan O, Saggar, Rajan, Steen, Virginia D, Strek, Mary E, Bernstein, Elana J, Bhatt, Nitin, Castelino, Flavia V, Chung, Lorinda, Domsic, Robyn T, Flaherty, Kevin R, Gupta, Nishant, Kahaleh, Bashar, Martinez, Fernando J, Morrow, Lee E, Moua, Teng, Patel, Nina, Shlobin, Oksana A, Southern, Brian D, Volkmann, Elizabeth R, Khanna, Dinesh

“…Systemic sclerosis (SSc) is a rare, complex, connective tissue disorder. Interstitial lung disease (ILD) is common in SSc, occurring in 35-52% of patients and…”
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Stretching the Function of Innate Immune Cells by Orsini, Erica M, Perelas, Apostolos, Southern, Brian D, Grove, Lisa M, Olman, Mitchell A, Scheraga, Rachel G

“…The importance of innate immune cells to sense and respond to their physical environment is becoming increasingly recognized. Innate immune cells (e.g…”
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The Role of TRPV4 in Regulating Innate Immune Cell Function in Lung Inflammation by Scheraga, Rachel G, Southern, Brian D, Grove, Lisa M, Olman, Mitchell A

“…Ion channels/pumps are essential regulators of innate immune cell function. Macrophages have been increasingly recognized to have phenotypic plasticity and…”
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The Role of Transient Receptor Potential Vanilloid 4 in Pulmonary Inflammatory Diseases by Scheraga, Rachel G, Southern, Brian D, Grove, Lisa M, Olman, Mitchell A

“…Ion channels/pumps are essential regulators of organ homeostasis and disease. In the present review, we discuss the role of the mechanosensitive cation…”
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Progression of kidney dysfunction in the community-dwelling elderly by Hemmelgarn, B.R., Zhang, J., Manns, B.J., Tonelli, M., Larsen, E., Ghali, W.A., Southern, D.A., McLaughlin, K., Mortis, G., Culleton, B.F.

“…Despite the high prevalence of chronic kidney disease among the elderly, few studies have described their loss of kidney function. We sought to determine the…”
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Prospective cohort of cryobiopsy in interstitial lung diseases: a single center experience by Ribeiro Neto, Manuel L, Arrossi, Andrea Valeria, Yadav, Ruchi, Culver, Daniel A, Mukhopadhyay, Sanjay, Parambil, Joseph G, Southern, Brian D, Tolle, Leslie, Pande, Aman, Almeida, Francisco A, Sahoo, Debasis, Glennie, Jessica, Ahmad, Usman, Mehta, Atul C, Gildea, Thomas R

“…Transbronchial cryobiopsy has been increasingly used to diagnose interstitial lung diseases. However, there is uncertainty regarding its accuracy and risks,…”
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Delphi Consensus Recommendations on Management of Dosing, Adverse Events, and Comorbidities in the Treatment of Idiopathic Pulmonary Fibrosis with Nintedanib by Rahaghi, Franck, Belperio, John A, Fitzgerald, John, Gulati, Mridu, Hallowell, Robert, Highland, Kristin B, Huie, Tristan J, Kim, Hyun J, Kolb, Martin, Lasky, Joseph A, Southern, Brian D, Swigris, Jeffrey J, de Andrade, Joao A

“…Purpose: Nintedanib is an approved treatment for idiopathic pulmonary fibrosis (IPF), which slows disease progression. Management of patients with IPF…”
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Thermotropic biaxial nematic order parameters and phase transitions deduced by Raman scattering by Southern, C. D, Brimicombe, P. D, Siemianowski, S. D, Jaradat, S, Roberts, N, Görtz, V, Goodby, J. W, Gleeson, H. F

“…Raman Scattering was used to investigate biaxiality in the nematic phase formed by the bent-core material, C5-Ph-ODBP-Ph-OC12. Linearly polarised light was…”
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CLINICAL UTILITY OF PRE-EXERCISE SCREENING USING EXERCISE STRESS TESTING IN PEOPLE WITH DIABETES by Armstrong, M, Rabi, D, Southern, D, Nanji, A, Ghali, W, Sigal, R

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Using the full Raman depolarisation in the determination of the order parameters in liquid crystal systems by SOUTHERN, C. D, GLEESON, H. F

“…The depolarisation ratio for the Raman-active phenyl stretching mode has been measured over the whole of the mesophase range, and the orientational order…”
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Developing a Data Integrated COVID-19 Tracking System for Decision-Making and Public Use by Krusina, A, Chen, O, Varela, L O, Doktorchik, C, Avati, V, Knudsen, S, Southern, D A, Eastwood, C, Sharma, N, Williamson, T

“…The unprecedented COVID-19 pandemic unveiled a strong need for advanced and informative surveillance tools. The Centre for Health Informatics (CHI) at the…”
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Patients with interstitial lung disease and pulmonary sarcoidosis are at high risk for severe illness related to COVID-19 by Southern, Brian D

“…Analyses of COVID-19 patients with preexisting interstitial lung disease (ILD) or pulmonary sarcoidosis is lacking but registries are ongoing. Treatment of…”
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Women's Recovery from Sternotomy-Extension (WREST-E) study: examining long-term pain and discomfort following sternotomy and their predictors by King, K M, Parry, M, Southern, D, Faris, P, Tsuyuki, R T

“…To examine incision and breast pain and discomfort, and their predictors in women 12 months following sternotomy. Extension survey following participation in a…”
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PROGNOSTIC VALUE OF ST-ELEVATION IN LEADS V1 FOR INFERIOR AND AVR FOR ANTERIOR STEMI UNDERGOING PRIMARY PCI by Har, B, Wong, J, Bizios, A, Galbraith, D, Southern, D, Zhang, M, Knudtson, M, Kuriachan, V

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The Association Between Pre-Operative Vascular Function and Outcomes Post-Coronary Artery Bypass Grafting by Martin, B, Southern, D, Galbraith, P.D, Ikanovic, M, Knudtson, M.L, Anderson, T.J

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Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription–free exponential amplification reaction, RTF-EXPAR by Carter, Jake G., Iturbe, Lorea Orueta, Duprey, Jean-Louis H. A., Carter, Ian R., Southern, Craig D., Rana, Marium, Whalley, Celina M., Bosworth, Andrew, Beggs, Andrew D., Hicks, Matthew R., Tucker, James H. R., Dafforn, Timothy R.

“…A rapid isothermal method for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, is reported. The…”
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TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice by Rahaman, Shaik O, Grove, Lisa M, Paruchuri, Sailaja, Southern, Brian D, Abraham, Susamma, Niese, Kathryn A, Scheraga, Rachel G, Ghosh, Sudakshina, Thodeti, Charles K, Zhang, David X, Moran, Magdalene M, Schilling, William P, Tschumperlin, Daniel J, Olman, Mitchell A

“…Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disorder with no effective medical treatments available. The generation of myofibroblasts, which…”
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Prevalent high-risk respiratory hygiene practices in urban and rural Bangladesh by Nasreen, S, Azziz-Baumgartner, E, Gurley, E.S, Winch, P.J, Unicomb, L, Sharker, M.A.Y, Southern, D, Luby, S.P

“…To identify existing respiratory hygiene risk practices, and guide the development of interventions for improving respiratory hygiene. We selected a…”
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