Search Results - "Southard, Chase R."

Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner by Al-Alem, Linah, Southard, R Chase, Kilgore, Michael W, Curry, Thomas E

“…Peroxisome Proliferator Activated Receptor gamma (PPARγ) agonists, such as the thiazolinediones (TZDs), have been studied for their potential use as cancer…”
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Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells by Zaytseva, Yekaterina Y, Wang, Xin, Southard, R Chase, Wallis, Natalie K, Kilgore, Michael W

“…Peroxisome proliferator-activated receptor gamma (PPARgamma) is a member of the nuclear hormone receptor superfamily and is highly expressed in many human…”
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MAZ drives tumor-specific expression of PPAR gamma 1 in breast cancer cells by Wang, Xin, Southard, R. Chase, Allred, Clinton D., Talbert, Dominique R., Wilson, Melinda E., Kilgore, Michael W.

“…The peroxisome proliferator-activated receptor gamma 1 (PPARγ1) is a nuclear receptor that plays a pivotal role in breast cancer and is highly over-expressed…”
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Activation of the PKC Pathway Stimulates Ovarian Cancer Cell Proliferation, Migration, and Expression of MMP7 and MMP10 by AL-ALEM, Linah F, MCCORD, Lauren A, SOUTHARD, R. Chase, KILGORE, Michael W, CURRY, Thomas E

“…Postmenopausal women are at a higher risk of ovarian cancer due, in part, to increased levels of gonadotropins such as luteinizing hormone (LH). Gonadotropins…”
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The complexity of signaling in host–pathogen interactions revealed by the Toxoplasma gondii-dependent modulation of JNK phosphorylation by Carmen, John C., Southard, R. Chase, Sinai, Anthony P.

“…The inhibition of apoptosis by Toxoplasma gondii is governed by its modulation of several signaling cascades including the NFκappaB and JNK pathways. This is…”
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The Increased Expression of Peroxisome Proliferator-Activated Receptor-γ1 in Human Breast Cancer Is Mediated by Selective Promoter Usage by Wang, Xin, Southard, R. Chase, Kilgore, Michael W.

“…Peroxisome proliferator-activated receptor-γ1 (PPARγ1) is transactivated by a wide range of ligands in normal human mammary epithelial and breast cancer cells…”
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Activation of the PKC Pathway Stimulates Ovarian Cancer cell Proliferation, Migration, and Expression of MMP7 and MMP10 by Al-Alem, Linah, McCord, Lauren, Southard, R. Chase, Kilgore, Michael, Curry, Thomas

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Defining Thiazolidinedione Targets in Ovarian Cancer to Identify Novel Diagnostic Markers by Al-Alem, Linah F., Southard, R. Chase, Kilgore, Michael W., Zhu, Haining, Curry, Thomas E.

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Specific Thiazolidinediones Inhibit Ovarian Cancer Cell Line Proliferation and Cause Cell Cycle Arrest in a PPAR[gamma] Independent Manner by Al-Alem, Linah, Southard, R. Chase, Kilgore, Michael W, Curry, Thomas E

“…Background Peroxisome Proliferator Activated Receptor gamma (PPAR[gamma]) agonists, such as the thiazolinediones (TZDs), have been studied for their potential…”
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Activation of the PKC Pathway Stimulates Ovarian Cancer Cell Proliferation, Migration, and Expression of MMP7 and MMP101 by Al-Alem, Linah F, McCord, Lauren A, Southard, R. Chase, Kilgore, Michael W, Curry, Thomas E

“…Postmenopausal women are at a higher risk of ovarian cancer due, in part, to increased levels of gonadotropins such as luteinizing hormone (LH). Gonadotropins…”
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Abstract 1723: Thiazolinediones (TZDs) mediate proliferation and cell cycle kinetics in ovarian cancer cells in a PPARγ-dependent and -independent manner by Al-Alem, Linah F., Southard, Chase R., Kilgore, Michael W., Curry, Thomas E.

“…Ovarian cancer is the leading cause of death in women with gynecological malignancies and is often called the ‘silent killer’. Thus, new treatment targets are…”
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The increased expression of peroxisome proliferator-activated receptor-gamma1 in human breast cancer is mediated by selective promoter usage by Wang, Xin, Southard, R Chase, Kilgore, Michael W

“…Peroxisome proliferator-activated receptor-gamma1 (PPARgamma1) is transactivated by a wide range of ligands in normal human mammary epithelial and breast…”
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The increased expression of peroxisome proliferator-activated receptor-γl in human breast cancer is mediated by selective promoter usage by XIN WANG, SOUTHARD, R. Chase, KILGORE, Michael W

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The PPARgamma antagonist T0070907 suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms by Zaytseva, Yekaterina Y, Wallis, Natalie K, Southard, R Chase, Kilgore, Michael W

“…Peroxisome proliferator-activated receptor gamma (PPARγ) is overexpressed in many types of cancer, including breast cancer, and it is regulated by ligand…”
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PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells by Allred, Clinton D, Talbert, Dominique R, Southard, R Chase, Wang, Xin, Kilgore, Michael W

“…Diets high in (n-3) PUFA decrease colon cancer development and suppress colon tumor growth, but the molecular mechanism through which these compounds act is…”
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Role of alpha -SNAP in Promoting Efficient Neurotransmission at the Crayfish Neuromuscular Junction by He, Ping, Southard, R. Chase, Chen, Dong, Whiteheart, S. W, Cooper, R. L

“…  1 T. H. Morgan School of Biological Science, University of Kentucky, Lexington 40506-0225; and   2 Department of Biochemistry, University of Kentucky College…”
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Influence of serotonin on the kinetics of vesicular release by Southard, R.Chase, Haggard, J, Crider, M.E, Whiteheart, S.W, Cooper, R.L

“…The mechanisms by which synaptic vesicles are transported and primed to fuse with the presynaptic membrane are important to all chemical synapses. Processes of…”
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