Search Results - "Southall, D"

Cell-Type-Specific Profiling of Gene Expression and Chromatin Binding without Cell Isolation: Assaying RNA Pol II Occupancy in Neural Stem Cells by Southall, Tony D., Gold, Katrina S., Egger, Boris, Davidson, Catherine M., Caygill, Elizabeth E., Marshall, Owen J., Brand, Andrea H.

“…Cell-type-specific transcriptional profiling often requires the isolation of specific cell types from complex tissues. We have developed “TaDa,” a technique…”
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DamID as a versatile tool for understanding gene regulation by Aughey, Gabriel N, Cheetham, Seth W, Southall, Tony D

“…The interaction of proteins and RNA with chromatin underlies the regulation of gene expression. The ability to profile easily these interactions is fundamental…”
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Visible Light Induces Melanogenesis in Human Skin through a Photoadaptive Response by Randhawa, Manpreet, Seo, InSeok, Liebel, Frank, Southall, Michael D, Kollias, Nikiforos, Ruvolo, Eduardo

“…Visible light (400-700 nm) lies outside of the spectral range of what photobiologists define as deleterious radiation and as a result few studies have studied…”
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Ets21c Governs Tissue Renewal, Stress Tolerance, and Aging in the Drosophila Intestine by Mundorf, Juliane, Donohoe, Colin D, McClure, Colin D, Southall, Tony D, Uhlirova, Mirka

“…Homeostatic renewal and stress-related tissue regeneration rely on stem cell activity, which drives the replacement of damaged cells to maintain tissue…”
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Dynamic adult tracheal plasticity drives stem cell adaptation to changes in intestinal homeostasis in Drosophila by Perochon, Jessica, Yu, Yachuan, Aughey, Gabriel N., Medina, André B., Southall, Tony D., Cordero, Julia B.

“…Coordination of stem cell function by local and niche-derived signals is essential to preserve adult tissue homeostasis and organismal health. The vasculature…”
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Neural stem cell transcriptional networks highlight genes essential for nervous system development by Southall, Tony D, Brand, Andrea H

“…Neural stem cells must strike a balance between self‐renewal and multipotency, and differentiation. Identification of the transcriptional networks regulating…”
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Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci by Sen, Sonia Q, Chanchani, Sachin, Southall, Tony D, Doe, Chris Q

“…Spatial and temporal cues are required to specify neuronal diversity, but how these cues are integrated in neural progenitors remains unknown. progenitors…”
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Targeted DamID reveals differential binding of mammalian pluripotency factors by Cheetham, Seth W, Gruhn, Wolfram H, van den Ameele, Jelle, Krautz, Robert, Southall, Tony D, Kobayashi, Toshihiro, Surani, M Azim, Brand, Andrea H

“…The precise control of gene expression by transcription factor networks is crucial to organismal development. The predominant approach for mapping…”
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Dedifferentiation of Neurons Precedes Tumor Formation in lola Mutants by Southall, Tony D., Davidson, Catherine M., Miller, Claire, Carr, Adrian, Brand, Andrea H.

“…The ability to reprogram differentiated cells into a pluripotent state has revealed that the differentiated state is plastic and reversible. It is evident,…”
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Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells by Korzelius, Jerome, Naumann, Svenja K, Loza-Coll, Mariano A, Chan, Jessica SK, Dutta, Devanjali, Oberheim, Jessica, Gläßer, Christine, Southall, Tony D, Brand, Andrea H, Jones, D Leanne, Edgar, Bruce A

“…Snail family transcription factors are expressed in various stem cell types, but their function in maintaining stem cell identity is unclear. In the adult…”
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Regulation of Drosophila intestinal stem cell maintenance and differentiation by the transcription factor Escargot by Loza-Coll, Mariano A, Southall, Tony D, Sandall, Sharsti L, Brand, Andrea H, Jones, D Leanne

“…Tissue stem cells divide to self‐renew and generate differentiated cells to maintain homeostasis. Although influenced by both intrinsic and extrinsic factors,…”
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An auxin-inducible, GAL4-compatible, gene expression system for Drosophila by McClure, Colin D, Hassan, Amira, Aughey, Gabriel N, Butt, Khushbakht, Estacio-Gómez, Alicia, Duggal, Aneisha, Ying Sia, Chee, Barber, Annika F, Southall, Tony D

“…The ability to control transgene expression, both spatially and temporally, is essential for studying model organisms. In , spatial control is primarily…”
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Avenanthramides, polyphenols from oats, exhibit anti-inflammatory and anti-itch activity by Sur, Runa, Nigam, Anu, Grote, Devon, Liebel, Frank, Southall, Michael D.

“…Oatmeal has been used for centuries as a soothing agent to relieve itch and irritation associated with various xerotic dermatoses; however few studies have…”
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CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in vivo by Aughey, Gabriel N, Estacio Gomez, Alicia, Thomson, Jamie, Yin, Hang, Southall, Tony D

“…During development eukaryotic gene expression is coordinated by dynamic changes in chromatin structure. Measurements of accessible chromatin are used…”
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Prospero Acts as a Binary Switch between Self-Renewal and Differentiation in Drosophila Neural Stem Cells by Choksi, Semil P., Southall, Tony D., Bossing, Torsten, Edoff, Karin, de Wit, Elzo, Fischer, Bettina E., van Steensel, Bas, Micklem, Gos, Brand, Andrea H.

“…Stem cells have the remarkable ability to give rise to both self-renewing and differentiating daughter cells. Drosophila neural stem cells segregate cell-fate…”
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Transcriptional control of stem cell maintenance in the Drosophila intestine by Bardin, Allison J, Perdigoto, Carolina N, Southall, Tony D, Brand, Andrea H, Schweisguth, François

“…Adult stem cells maintain tissue homeostasis by controlling the proper balance of stem cell self-renewal and differentiation. The adult midgut of Drosophila…”
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Dam it's good! DamID profiling of protein-DNA interactions by Aughey, Gabriel N, Southall, Tony D

“…The interaction of proteins with chromatin is fundamental for several essential cellular processes. During the development of an organism, genes must to be…”
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Monitoring intrapartum fetal heart rates by mothers in labour in two public hospitals: an initiative to improve maternal and neonatal healthcare in Liberia by Borzie, K, Jasper, N, Southall, D P, MacDonald, R, Kola, A A, Dolo, O, Magnus, A, Watson, S D, Casement, M, Dahn, B, Jallah, W

“…In low-resource settings with few health workers, Fetal Heart Rate (FHR) monitoring in labour can be inconsistent and unreliable. An initiative to improve…”
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First application of Markov chain Monte Carlo-based Bayesian data analysis to the Doppler-shift attenuation method by Sun, L.J., Fry, C., Davids, B., Esker, N., Wrede, C., Alcorta, M., Bhattacharjee, S., Bowry, M., Brown, B.A., Budner, T., Caballero-Folch, R., Evitts, L., Friedman, M., Garnsworthy, A.B., Glassman, B.E., Hackman, G., Henderson, J., Kirsebom, O.S., Lighthall, J., Machule, P., Measures, J., Moukaddam, M., Park, J., Pearson, C., Pérez-Loureiro, D., Ruiz, C., Ruotsalainen, P., Smallcombe, J., Smith, J.K., Southall, D., Surbrook, J., Weghorn, L.E., Williams, M.

“…Motivated primarily by the large uncertainties in the thermonuclear rate of the 30P(p,γ)31S reaction that limit our understanding of classical novae, we…”
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Keratinocyte differentiation and upregulation of ceramide synthesis induced by an oat lipid extract via the activation of PPAR pathways by Chon, Su-Hyoun, Tannahill, Ruth, Yao, Xiang, Southall, Michael D., Pappas, Apostolos

“…Activation of peroxisome proliferator‐activated receptors (PPARs) has been shown to have an important role in skin barrier function by regulating…”
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