Search Results - "Soustelle, Laurent"
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The ALS-associated KIF5A P986L variant is not pathogenic for Drosophila motoneurons
Published in Scientific reports (22-08-2024)“…Amyotrophic lateral sclerosis (ALS) is a devastating paralytic disorder caused by the death of motoneurons. Several mutations in the KIF5A gene have been…”
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2
Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster
Published in International journal of molecular sciences (18-01-2021)“…Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disease characterized by the progressive degeneration of upper and lower…”
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3
Honey Bee Allatostatins Target Galanin/Somatostatin-Like Receptors and Modulate Learning: A Conserved Function?
Published in PloS one (07-01-2016)“…Sequencing of the honeybee genome revealed many neuropeptides and putative neuropeptide receptors, yet functional characterization of these peptidic systems is…”
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4
Can childbearing spinal cord injury women with continent cutaneous urinary diversion have child?
Published in Urol Ann (01-01-2022)“…Over the last half century, significant improvements in health outcomes for individuals with spinal cord injury (SCI) and growing recognition those women with…”
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5
Plant insecticide L-canavanine repels Drosophila via the insect orphan GPCR DmX
Published in PLoS biology (30-06-2009)“…For all animals, the taste sense is crucial to detect and avoid ingesting toxic molecules. Many toxins are synthesized by plants as a defense mechanism against…”
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6
Novel gcm‐dependent lineages in the postembryonic nervous system of Drosophila melanogaster
Published in Developmental dynamics (01-08-2007)“…glial cells missing genes (gcm and gcm2) act as the glial fate determinants in the Drosophila embryo. However, their requirement in the adult central nervous…”
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7
Decreasing Glutamate Buffering Capacity Triggers Oxidative Stress and Neuropil Degeneration in the Drosophila Brain
Published in Current biology (06-04-2004)“…L-glutamate is both the major brain excitatory neurotransmitter [1, 2] and a potent neurotoxin [3, 4] in mammals. Glutamate excitotoxicity is partly…”
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8
A New Behavioral Test and Associated Genetic Tools Highlight the Function of Ventral Abdominal Muscles in Adult Drosophila
Published in Frontiers in cellular neuroscience (21-11-2017)“…The function of the nervous system in complex animals is reflected by the achievement of specific behaviors. For years in , both simple and complex behaviors…”
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9
Gαo is required for L-canavanine detection in Drosophila
Published in PloS one (06-05-2013)“…Taste is an essential sense for the survival of most organisms. In insects, taste is particularly important as it allows to detect and avoid ingesting many…”
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10
Neurogenic role of Gcm transcription factors is conserved in chicken spinal cord
Published in Development (Cambridge) (01-02-2007)“…Although glial cells missing ( gcm ) genes are known as glial determinants in the fly embryo, the role of vertebrate orthologs in the central nervous system is…”
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11
DPP signaling controls development of the lamina glia required for retinal axon targeting in the visual system of Drosophila
Published in Development (Cambridge) (01-10-2005)“…The Drosophila visual system consists of the compound eyes and the optic ganglia in the brain. Among the eight photoreceptor (R) neurons, axons from the R1-R6…”
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12
UV laser mediated cell selective destruction by confocal microscopy
Published in Neural development (28-04-2008)“…Analysis of cell-cell interactions, cell function and cell lineages greatly benefits selective destruction techniques, which, at present, rely on dedicated,…”
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13
Terminal Glial Differentiation Involves Regulated Expression of the Excitatory Amino Acid Transporters in the Drosophila Embryonic CNS
Published in Developmental biology (15-08-2002)“…The Drosophila excitatory amino acid transporters dEAAT1 and dEAAT2 are nervous-specific transmembrane proteins that mediate the high affinity uptake of…”
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14
Terminal tendon cell differentiation requires the glide/gcm complex
Published in Development (Cambridge) (15-09-2004)“…Locomotion relies on stable attachment of muscle fibres to their target sites, a process that allows for muscle contraction to generate movement. Here, we show…”
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15
Identification and structural characterization of two genes encoding glutamate transporter homologues differently expressed in the nervous system of Drosophila melanogaster
Published in FEBS letters (29-01-1999)“…In vertebrates, excitatory amino acid transporters (EAATs) are believed to mediate the removal of glutamate released at excitatory synapses and to maintain…”
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16
Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster
Published in International journal of molecular sciences (18-01-2021)“…Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disease characterized by the progressive degeneration of upper and lower…”
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Journal Article -
17
ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss
Published in The Journal of neuroscience (22-11-2023)“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Recently, genome-wide association studies identified KIF5A as…”
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18
Long-Term Results of Artificial Urinary Sphincter for Women with Type III Stress Urinary Incontinence
Published in European urology (01-04-2013)“…Abstract Background The use of the artificial urinary sphincter (AUS) in women is limited. Objective To analyse long-term results and mechanical survival of…”
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19
Dual mechanism for bitter avoidance in Drosophila
Published in The Journal of neuroscience (04-03-2015)“…In flies and humans, bitter chemicals are known to inhibit sugar detection, but the adaptive role of this inhibition is often overlooked. At best, this…”
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20
A prospective comparison of surgical and pathological outcomes obtained after robot‐assisted or pure laparoscopic partial nephrectomy in moderate to complex renal tumours: results from a French multicentre collaborative study
Published in BJU international (01-02-2013)“…What's known on the subject? and What does the study add? Nephron‐sparing surgery has become the standard of care for small renal masses because it allows for…”
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