Search Results - "Sousa Barbosa, Karla Patrícia"
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Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl_4^-) Induced Liver Injury in Mice
Published in Mediators of Inflammation (01-01-2014)“…This study investigated the anti-inflammatory effects of DEC on the CCl4-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p…”
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Involvement of AMPK, IKβα-NFκB and eNOS in the sildenafil anti-inflammatory mechanism in a demyelination model
Published in Brain research (19-11-2015)“…Abstract Sildenafil (Viagra®) has recently been found to have a neuroprotective effect, which occurs through the inhibition of inflammation and demyelination…”
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Effect of diethylcarbamazine on chronic hepatic inflammation induced by alcohol in C57BL/6 mice
Published in European journal of pharmacology (15-08-2012)“…Some pharmacological studies showed that diethylcarbamazine (DEC) interferes with the arachidonic acid metabolism, acting as an anti-inflammatory drug. The…”
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Diethylcarbamazine inhibits NF-κB activation in acute lung injury induced by carrageenan in mice
Published in International immunopharmacology (01-11-2014)“…Diethylcarbamazine citrate (DEC) is widely used to treat lymphatic filariasis and Tropical Pulmonary Eosinophilia. A number of studies have reported a possible…”
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Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice
Published in Brain research (01-08-2016)“…Abstract The aim of the present study was to analyze the action of metformin on short-term memory, glial cell activation and neuroinflammation caused by…”
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Diethylcarbamazine attenuates LPS-induced acute lung injury in mice by apoptosis of inflammatory cells
Published in Pharmacological reports (01-02-2017)“…Acute lung injury (ALI) is characterized by extensive neutrophil infiltration, and apoptosis delay considered part of the pathogenesis of the condition…”
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Diethylcarbamazine attenuates the expression of pro-fibrogenic markers and hepatic stellate cells activation in carbon tetrachloride-induced liver fibrosis
Published in Inflammopharmacology (01-04-2018)“…Background and aim While diethylcarbamazine citrate (DEC) displays important anti-inflammatory effects in experimental models of liver injury, the mechanisms…”
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Effects of Sildenafil Citrate and Heparin Treatments on Placental Cell Morphology in a Murine Model of Pregnancy Loss
Published in Cells, tissues, organs (2016)“…Lipopolysaccharide (LPS) injections during pregnancy are well established as models for pregnancy complications, including fetal growth restriction (FGR),…”
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