Search Results - "Sousa, Sérgio"

Special Issue on "Enzymes as Biocatalysts: Current Research Trends and Applications" by Sousa, Sérgio F

“…Enzymes are able to catalyze a wide diversity of chemical reactions in nature, and they do it at an amazing level [...]…”
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A compositional link between rocky exoplanets and their host stars by Adibekyan, Vardan, Dorn, Caroline, Sousa, Sérgio G, Santos, Nuno C, Bitsch, Bertram, Israelian, Garik, Mordasini, Christoph, Barros, Susana C C, Delgado Mena, Elisa, Demangeon, Olivier D S, Faria, João P, Figueira, Pedro, Hakobyan, Artur A, Oshagh, Mahmoudreza, Soares, Bárbara M T B, Kunitomo, Masanobu, Takeda, Yoichi, Jofré, Emiliano, Petrucci, Romina, Martioli, Eder

“…Stars and planets both form by accreting material from a surrounding disk. Because they grow from the same material, theory predicts that there should be a…”
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Curcumin and 10-undecenoic acid as natural quorum sensing inhibitors of LuxS/AI-2 of Bacillus subtilis and LasI/LasR of Pseudomonas aeruginosa by Fernandes, Susana, Borges, Anabela, Gomes, Inês B., Sousa, Sérgio F., Simões, Manuel

“…[Display omitted] •In silico analysis selected curcumin and 10-undecenoic acid as anti-QS molecules.•Curcumin and 10-undecenoic acid showed in vitro anti-QS…”
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Valorization of By-Products from Commercial Fish Species: Extraction and Chemical Properties of Skin Gelatins by Sousa, Sérgio C, Vázquez, José A, Pérez-Martín, Ricardo I, Carvalho, Ana P, Gomes, Ana M

“…Fish skins constitute an important fraction of the enormous amount of wastes produced by the fish processing industry, part of which may be valorized through…”
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General Performance of Density Functionals by Sousa, Sérgio Filipe, Fernandes, Pedro Alexandrino, Ramos, Maria João

“…The density functional theory (DFT) foundations date from the 1920s with the work of Thomas and Fermi, but it was after the work of Hohenberg, Kohn, and Sham…”
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The buzz on insecticides: a review of uses, molecular structures, targets, adverse effects, and alternatives by Araújo, Maria F., Castanheira, Elisabete M. S., Sousa, Sérgio F.

“…Insecticides play a critical role in controlling the spread of insect-borne diseases and preserving crop health. These chemical substances are specifically…”
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Albright's Hereditary Osteodystrophy: an Entity to Recognize by Maduro, Ana Isabel, Saraiva, André Pinto, Pimenta Rodrigues, Orlando, Marques, Marta, Sousa, Sérgio B, Malcata, Armando, Perez de Nanclares, Guiomar, Serra, Sara

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Identification of New Potential Inhibitors of Quorum Sensing through a Specialized Multi-Level Computational Approach by Martins, Fábio G, Melo, André, Sousa, Sérgio F

“…Biofilms are aggregates of microorganisms anchored to a surface and embedded in a self-produced matrix of extracellular polymeric substances and have been…”
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Reaction Mechanism and Determinants for Efficient Catalysis by DszB, a Key Enzyme for Crude Oil Bio-desulfurization by Sousa, João P. M, Neves, Rui P. P, Sousa, Sérgio F, Ramos, Maria J, Fernandes, Pedro A

“…Sulfur oxides emitted by the burning of fossil fuels are a major environmental hazard. Strict legislation limits the sulfur content in fuels to ultralow…”
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Factors impacting the microbial production of eicosapentaenoic acid by Sousa, Sérgio, Carvalho, Ana P., Gomes, Ana M.

“…The increasing applications for eicosapentaenoic acid (EPA) and the potential shortfall in supply due to sustainability and contamination issues related with…”
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Comparing AutoDock and Vina in Ligand/Decoy Discrimination for Virtual Screening by Vieira, Tatiana F., Sousa, Sérgio F.

“…AutoDock and Vina are two of the most widely used protein–ligand docking programs. The fact that these programs are free and available under an open source…”
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LC-ESI-UHR-QqTOF-MS/MS profiling and anti-inflammatory potential of the cultivated Opuntia ficus-indica (L.) Mill. and the wild Opuntia stricta (Haw.) Haw. fruits from the Algerian region by Zeghbib, Walid, Boudjouan, Fares, Carneiro, João, Oliveira, Ana L.S., Sousa, Sérgio F., Pintado, Manuela Estevez, Ourabah, Asma, Vasconcelos, Vitor, Lopes, Graciliana

“…Opuntia plants are abundant but still underexplored edible resources of the Algerian region. This work chemically characterizes extracts of different parts of…”
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Modelling Enzymatic Mechanisms with QM/MM Approaches: Current Status and Future Challenges by Magalhães, Rita P., Fernandes, Henriques S., Sousa, Sérgio F.

“…Quantum mechanics/molecular mechanics (QM/MM) methods are presently a well‐established alternative for the study of enzymatic reaction mechanisms. They enable…”
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Protein-ligand docking: Current status and future challenges by Sousa, Sérgio Filipe, Fernandes, Pedro Alexandrino, Ramos, Maria João

“…Understanding the ruling principles whereby protein receptors recognize, interact, and associate with molecular substrates and inhibitors is of paramount…”
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Films of chitosan and natural modified hydroxyapatite as effective UV-protecting, biocompatible and antibacterial wound dressings by Cunha, Carla S., Castro, Pedro J., Sousa, Sérgio C., Pullar, Robert C., Tobaldi, David M., Piccirillo, Clara, Pintado, Maria M.

“…Chitosan is a natural polysaccharide widely used in biomedicine, for instance for wound dressing. Hydroxyapatite is a very bioactive calcium phosphate which,…”
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A Molecular Perspective on Sirtuin Activity by Teixeira, Carla S S, Cerqueira, Nuno M F S A, Gomes, Pedro, Sousa, Sérgio F

“…The protein acetylation of either the α-amino groups of amino-terminal residues or of internal lysine or cysteine residues is one of the major…”
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An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia by Gesto, Diana S, Pereira, Carlos M S, Cerqueira, Nuno M F S, Sousa, Sérgio F

“…This review provides an updated atomic-level perspective regarding the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoAR), linking the more…”
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Non-B DNA conformations analysis through molecular dynamics simulations by Pina, André F., Sousa, Sérgio F., Azevedo, Luísa, Carneiro, João

“…Non-B DNA conformations are molecular structures that do not follow the canonical DNA double helix. Mutagenetic instability in nuclear and mitochondrial DNA…”
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Pycnodysostosis: A rare cause of pathological fractures and exuberant clinical manifestations in two sisters by Sousa, Marlene, Prata, Ana Rita, Maduro, Ana Isabel, Sousa, Sérgio B., Malcata, Armando

“…•Pycnodysostosis is a rare inherited lysosomal storage disorder having a typical phenotype.•Most clinical manifestations are evident from an early age, but…”
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Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET by Magalhães, Rita P, Cunha, Jorge M, Sousa, Sérgio F

“…Plastics are highly durable and widely used materials. Current methodologies of plastic degradation, elimination, and recycling are flawed. In recent years,…”
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