Search Results - "Sousa, Rui A"

Impact of aging on the 6-OHDA-induced rat model of Parkinson’s disease by Barata-Antunes, Sandra, Teixeira, Fábio G., Mendes-Pinheiro, Bárbara, Domingues, Ana V., Vilaça-Faria, Helena, Marote, Ana, Silva, Deolinda, Sousa, R. A., Salgado, A. J.

“…Parkinson’s disease (PD) is the second most common age-related neurodegenerative disorder. The neurodegeneration leading to incapacitating motor abnormalities…”
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Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone–starch scaffold and the in vitro development of vascularization by Santos, Marina I, Unger, Ronald E, Sousa, Rui A, Reis, Rui L, Kirkpatrick, C. James

“…Abstract The reconstruction of bone defects based on cell-seeded constructs requires a functional microvasculature that meets the metabolic demands of the…”
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In vitro model of vascularized bone: synergizing vascular development and osteogenesis by Correia, Cristina, Grayson, Warren L, Park, Miri, Hutton, Daphne, Zhou, Bin, Guo, X Edward, Niklason, Laura, Sousa, Rui A, Reis, Rui L, Vunjak-Novakovic, Gordana

“…Tissue engineering provides unique opportunities for regenerating diseased or damaged tissues using cells obtained from tissue biopsies. Tissue engineered…”
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In Vitro Cytotoxicity Assessment of Ulvan, a Polysaccharide Extracted from Green Algae by Alves, Anabela, Sousa, Rui A., Reis, Rui L.

“…Sustainable exploitation and valorization of natural marine resources represents a highly interesting platform for the development of novel biomaterials, with…”
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Processing of degradable ulvan 3D porous structures for biomedical applications by Alves, Anabela, Sousa, Rui A., Reis, Rui L.

“…The interest in ulvan within a biomedical framework increases as the knowledge of this polysaccharide evolves. Ulvan has been recently proposed as a potential…”
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Mussel-Inspired Catechol Functionalisation as a Strategy to Enhance Biomaterial Adhesion: A Systematic Review by Costa, Pedro M., Learmonth, David A., Gomes, David B., Cautela, Mafalda P., Oliveira, Ana C. N., Andrade, Renato, Espregueira-Mendes, João, Veloso, Tiago R., Cunha, Cristiana B., Sousa, Rui A.

“…Biomaterials have long been explored in regenerative medicine strategies for the repair or replacement of damaged organs and tissues, due to their…”
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Characterization of ulvan extracts to assess the effect of different steps in the extraction procedure by Costa, Carina, Alves, Anabela, Pinto, Paula R., Sousa, Rui A., Borges da Silva, Eduardo A., Reis, Rui L., Rodrigues, Alírio E.

“…► A sulfated polysaccharide, ulvan, was extracted from green algae and purified. ► The composition were assessed by multiple and complementary methodologies. ►…”
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Effect of scaffold architecture and BMP-2/BMP-7 delivery on in vitro bone regeneration by Yilgor, Pinar, Sousa, Rui A., Reis, Rui L., Hasirci, Nesrin, Hasirci, Vasif

“…The aim of this study was to develop 3-D tissue engineered constructs that mimic the in vivo conditions through a self-contained growth factor delivery system…”
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Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments by Mano, João F, Sousa, Rui A, Boesel, Luciano F, Neves, Nuno M, Reis, Rui L

“…The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applications. The review presents the…”
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Hierarchical starch-based fibrous scaffold for bone tissue engineering applications by Martins, Albino, Chung, Sangwon, Pedro, Adriano J., Sousa, Rui A., Marques, Alexandra P., Reis, Rui L., Neves, Nuno M.

“…Fibrous structures mimicking the morphology of the natural extracellular matrix are considered promising scaffolds for tissue engineering. This work aims to…”
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The Role of Biomaterials as Angiogenic Modulators of Spinal Cord Injury: Mimetics of the Spinal Cord, Cell and Angiogenic Factor Delivery Agents by Rocha, Luís A, Sousa, Rui A, Learmonth, David A, Salgado, António J

“…Spinal cord injury (SCI) represents an extremely debilitating condition for which no efficacious treatment is available. One of the main contributors to the…”
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In vitro Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization by Rocha, Luís A., Gomes, Eduardo D., Afonso, João L., Granja, Sara, Baltazar, Fatima, Silva, Nuno A., Shoichet, Molly S., Sousa, Rui A., Learmonth, David A., Salgado, Antonio J.

“…Vascular disruption following spinal cord injury (SCI) decisively contributes to the poor functional recovery prognosis facing patients with the condition…”
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Plasma-induced polymerization as a tool for surface functionalization of polymer scaffolds for bone tissue engineering: An in vitro study by López-Pérez, Paula M., da Silva, Ricardo M.P., Sousa, Rui A., Pashkuleva, Iva, Reis, Rui L.

“…A commonly applied strategy in the field of tissue engineering (TE) is the use of temporary three-dimensional scaffolds for supporting and guiding tissue…”
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In vivo study of dendronlike nanoparticles for stem cells “ tune-up ”: from nano to tissues by Oliveira, Joaquim M., PhD, Sousa, Rui A., PhD, Malafaya, Patricia B., PhD, Silva, Simone S., PhD, Kotobuki, Noriko, PhD, Hirose, Motohiro, PhD, Ohgushi, Hajime, MD, PhD, Mano, João F., PhD, Reis, Rui L., PhD

“…Abstract The control of stem cell differentiation to obtain osteoblasts in vivo is still regarded as a challenge in stem-cell-based and bone-tissue engineering…”
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practical perspective on ulvan extracted from green algae by Alves, Anabela, Sousa, Rui A, Reis, Rui L

“…Researchers have many times turned their attention to nature and biological processes to develop novel technologies and materials. In a medical perspective,…”
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Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency by Sobral, Jorge M., Caridade, Sofia G., Sousa, Rui A., Mano, João F., Reis, Rui L.

“…Scaffolds produced by rapid prototyping (RP) techniques have proved their value for tissue engineering applications, due to their ability to produce…”
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αvβ3 and α5β1 integrin-specific ligands: From tumor angiogenesis inhibitors to vascularization promoters in regenerative medicine? by Rocha, Luís A., Learmonth, David A., Sousa, Rui A., Salgado, António J.

“…Integrins are cell adhesion receptors predominantly important during normal and tumor angiogenesis. A sequence present on several extracellular matrix proteins…”
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Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells by Correia, Cristina, Bhumiratana, Sarindr, Yan, Le-Ping, Oliveira, Ana L., Gimble, Jeffrey M., Rockwood, Danielle, Kaplan, David L., Sousa, Rui A., Reis, Rui L., Vunjak-Novakovic, Gordana

“…Silk fibroin is a potent alternative to other biodegradable biopolymers for bone tissue engineering (TE), because of its tunable architecture and mechanical…”
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Hydrogel-based magnetoelectric microenvironments for tissue stimulation by Hermenegildo, B., Ribeiro, C., Pérez-Álvarez, L., Vilas, José L., Learmonth, David A., Sousa, Rui A., Martins, P., Lanceros-Méndez, S.

“…[Display omitted] •New injectable magneto‐sensitive GGMA-based hydrogels have been developed.•The magnetoelectric spheres introduction into the hydrogel…”
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Bilayered silk/silk-nanoCaP scaffolds for osteochondral tissue engineering: In vitro and in vivo assessment of biological performance by Yan, Le-Ping, Silva-Correia, Joana, Oliveira, Mariana B., Vilela, Carlos, Pereira, Hélder, Sousa, Rui A., Mano, João F., Oliveira, Ana L., Oliveira, Joaquim M., Reis, Rui L.

“…[Display omitted] Novel porous bilayered scaffolds, fully integrating a silk fibroin (SF) layer and a silk-nano calcium phosphate (silk-nanoCaP) layer for…”
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