Search Results - "Sousa, Lorena"
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1
Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: Inhibition kinetics and docking studies
Published in Bioorganic & medicinal chemistry (01-02-2015)“…[Display omitted] NS2B-NS3 is a serine protease of the Dengue virus considered a key target in the search for new antiviral drugs. In this study flavonoids…”
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2
Inhibition of Leishmania amazonensis arginase by fucogalactan isolated from Agrocybe aegerita mushroom
Published in Carbohydrate polymers (01-12-2018)“…•A fucogalactan (FG-Aa) was purified from the medicinal mushroom Agrocybe aegerita.•The fucogalactan was highly branched by non-reducing ends of α-Fucp.•FG-Aa…”
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3
COVID-19 gastrointestinal manifestations: a systematic review
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has greatly challenged public health worldwide. A growing number…”
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4
Sanitization at different times after floor egg collection for hatchability, microbiological quality, and performance of broilers
Published in Poultry science (01-12-2023)“…In this study, the effects of egg type and sanitization time on eggshell and yolk sac microbiological quality, hatchability, and broiler performance at 7 and…”
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Phosphoenolpyruvate carboxykinase from T. cruzi magnetic beads affinity-based screening assays on crude plant extracts from Brazilian Cerrado
Published in Journal of pharmaceutical and biomedical analysis (30-01-2021)“…[Display omitted] •Cerrado Brazilian plants ethanolic extract as natural products library.•High specificity affinity-based assay for PEPCK.•Eleven ligands…”
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6
Natural products as inhibitors of recombinant cathepsin L of Leishmania mexicana
Published in Experimental parasitology (01-09-2015)“…•Natural products were screened against L. mexicana cathepsin L (rCPB2.8).•A triterpene and some flavonoids are inhibitors of rCPB2.8.•The inhibitors of…”
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Acetogenins-Rich Fractions of Annona coriacea Suppress Human Glioblastoma Viability and Migration by Regulating Necroptosis and MMP-2 Activity In Vitro
Published in Molecules (Basel, Switzerland) (29-04-2023)“…Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis. Resection, radiation therapy, and temozolomide (TMZ) are insufficient to increase…”
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Chemical Prospection of Qualea grandiflora Mart. Fruit and Stem Extracts and Their in vitro and in vivo Antiplasmodial Activity
Published in Journal of the Brazilian Chemical Society (01-07-2020)“…Qualea grandiflora Mart. (“pau-terra”) is a medicinal plant symbolic from Cerrado biome. Qualea species reportedly have antiparasitic properties, but their…”
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9
Metabolites from Marine Sponges and Their Potential to Treat Malarial Protozoan Parasites Infection: A Systematic Review
Published in Marine drugs (28-02-2021)“…Malaria is an infectious disease caused by protozoan parasites of the genus through the bite of female Anopheles mosquitoes, affecting 228 million people and…”
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10
Using molecular networking and docking to explore arginase inhibitors among Drimys brasiliensis chemical constituents
Published in Medicinal chemistry research (01-10-2023)“…Arginase is a potential target of drugs against Leishmania spp. Natural products can be a source of arginase inhibitors. This study has investigated whether…”
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NEW DEGRADED QUINONE DITERPENOID FROM THE STEMS OF Byrsonima coccolobifolia Kunth. (Malpighiaceae)
Published in Química Nova (01-02-2018)“…A chemical investigation of two specimens of Byrsonima coccolobifolia collected in the southeast cerrado and from central Brazil was performed. A new degraded…”
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12
Factors associated with tuberculosis by HIV status in the Brazilian national surveillance system: a cross sectional study
Published in BMC infectious diseases (28-07-2014)“…Over the last decade tuberculosis (TB) incidence and mortality in Brazil have been steadily declining. However, this downward trend has not been observed among…”
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13
Use of botulinum toxin for the treatment of keloid scars: scoping review
Published in Revista Brasileira de cirurgia plástica (01-04-2024)“…Introduction: Visible scars can cause problems, whether aesthetic, psychological, functional, or social, mainly of great extension and volume, such as keloids…”
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14
Perspectives for the use of plant extracts to control the cattle tick Rhipicephalus (Boophilus) microplus
Published in Revista brasileira de parasitologia veterinaria (01-04-2011)“…The evolution of resistance of Rhipicephalus (Boophilus) microplus to synthetic acaricides has given rise to the need for new scientific investigations on…”
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15
Does dredging activity exert an influence on benthic macrofauna in tropical estuaries? Case study on the northern coast of Brazil
Published in Iheringia. Série zoologia (01-01-2023)“…ABSTRACT The aim of the present study was to investigate the effect of dredging activities on the structure of the macrobenthic community of a port complex in…”
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16
New cathepsin V inhibitor from stems of Bowdichia virgilioides
Published in Revista brasileira de farmacognosia (01-07-2019)“…[Display omitted] Bioassay-guided fractionation of Bowdichia virgilioides Kunth, Fabaceae, extracts has led to the isolation of cathepsin V inhibitors. The…”
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17
Fiber source and xylanase on performance, egg quality, and gastrointestinal tract of laying hens
Published in Revista brasileira de zootecnia (01-01-2019)“…ABSTRACT The objective of this study was to ascertain the influence of different dietary fiber sources and the usage of xylanase on diet of commercial layers…”
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18
Mycotoxins from Fusarium proliferatum: new inhibitors of papain-like cysteine proteases
Published in Brazilian journal of microbiology (01-09-2020)“…Papain-like cysteine proteases (PLCPs) in plants are essential to prevent phytopathogen invasion. In order to search for cysteine protease inhibitors and to…”
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Genetic diversity and population structure of sugarcane (Saccharum spp.) accessions by means of microsatellites markers
Published in Acta scientiarum. Agronomy (01-01-2020)“…The success of sugarcane (Saccharum spp.) breeding programs depends on the choice of productive parent lines that have a high industrial yield and are…”
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Prevalence of visceral leishmaniasis in A population of free-roaming dogs as determined by multiple sampling efforts: A longitudinal study analyzing the effectiveness of euthanasia
Published in Preventive veterinary medicine (01-12-2018)“…Free-roaming dogs affected by visceral leishmaniasis (VL) contribute to the geographical expansion of the disease and require special attention from health…”
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