Search Results - "Sousa, Elsa Joana"
-
1
MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis
Published in Cell death & disease (07-02-2018)“…Upregulation of MYC and miRNAs deregulation are common in prostate cancer (PCa). Overactive MYC may cause miRNAs’ expression deregulation through…”
Get full text
Journal Article -
2
SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3
Published in Oncotarget (30-05-2015)“…Prostate cancer (PCa) is one of the most incident cancers worldwide but clinical and pathological parameters have limited ability to discriminate between…”
Get full text
Journal Article -
3
Anti-tumoral effect of the non-nucleoside DNMT inhibitor RG108 in human prostate cancer cells
Published in Current pharmaceutical design (01-04-2014)“…Current therapeutic strategies for advanced prostate cancer (PCa) are largely ineffective. Because aberrant DNA methylation associated with inappropriate…”
Get more information
Journal Article -
4
Anti-neoplastic properties of hydralazine in prostate cancer
Published in Oncotarget (15-08-2014)“…Prostate cancer (PCa) is a major cause of cancer-related morbidity and mortality worldwide. Although early disease is often efficiently managed…”
Get full text
Journal Article -
5
Enoxacin inhibits growth of prostate cancer cells and effectively restores microRNA processing
Published in Epigenetics (01-05-2013)“…Prostate cancer (PCa) is one of the most incident malignancies worldwide. Although efficient therapy is available for early-stage PCa, treatment of advanced…”
Get full text
Journal Article -
6
Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer
Published in Oncotarget (01-10-2013)“…Histone variants seem to play a major role in gene expression regulation. In prostate cancer, H2A.Z and its acetylated form are implicated in oncogenes'…”
Get full text
Journal Article -
7
Assessment of Enoxacin Effect on Cancer Growth and Microrna Expression in Prostate Cell Lines
Published 01-01-2012“…Background: Prostate cancer (PCa) is one of the most incident malignancies worldwide and represents a leading cause of cancer-related morbidity and…”
Get full text
Dissertation