Synthesis of new Bis- and Tetra-Acridines

A new series of bis- and tetra-acridines has been prepared from 4-(bromomethyl) acridine; some of them exhibited encouraging in vitro cytotoxic activities against murine cell lines.

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Vol. 6; no. 8; pp. 673 - 682
Main Authors:	Sourdon, Valérie, Mazoyer, Stéphane, Pique, Valérie, Galy, Jean-Pierre
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 01-08-2001 MDPI
Subjects:	Acridines amines Biological activity diamines Leukemia Ligands N-alkylation polycycles
Online Access:	Get full text
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Description
Summary:	A new series of bis- and tetra-acridines has been prepared from 4-(bromomethyl) acridine; some of them exhibited encouraging in vitro cytotoxic activities against murine cell lines.
ISSN:	1420-3049 1420-3049
DOI:	10.3390/60800673