Search Results - "Soundararajan, Venkataramanan"

Engineering and optimising deaminase fusions for genome editing by Yang, Luhan, Briggs, Adrian W., Chew, Wei Leong, Mali, Prashant, Guell, Marc, Aach, John, Goodman, Daniel Bryan, Cox, David, Kan, Yinan, Lesha, Emal, Soundararajan, Venkataramanan, Zhang, Feng, Church, George

“…Precise editing is essential for biomedical research and gene therapy. Yet, homology-directed genome modification is limited by the requirements for genomic…”
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Recombinant Expression, Purification, and Biochemical Characterization of Chondroitinase ABC II from Proteus vulgaris by Prabhakar, Vikas, Capila, Ishan, Soundararajan, Venkataramanan, Raman, Rahul, Sasisekharan, Ram

“…Chondroitin lyases (or chondroitinases) are a family of enzymes that depolymerize chondroitin sulfate (CS) and dermatan sulfate (DS) galactosaminoglycans,…”
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Atomic interaction networks in the core of protein domains and their native folds by Soundararajan, Venkataramanan, Raman, Rahul, Raguram, S, Sasisekharan, V, Sasisekharan, Ram

“…Vastly divergent sequences populate a majority of protein folds. In the quest to identify features that are conserved within protein domains belonging to the…”
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Correction: Corrigendum: Engineering and optimising deaminase fusions for genome editing by Yang, Luhan, Briggs, Adrian W., Chew, Wei Leong, Mali, Prashant, Guell, Marc, Aach, John, Goodman, Daniel Bryan, Cox, David, Kan, Yinan, Lesha, Emal, Soundararajan, Venkataramanan, Zhang, Feng, Church, George

“…Nature Communications 7: Article number: 13330 (2016); Published 2 November 2016; Updated 9 October 2017. The original version of this Article contained an…”
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Heparin/Heparan Sulfate 6-O-Sulfatase from Flavobacterium heparinum by Myette, James R., Soundararajan, Venkataramanan, Shriver, Zachary, Raman, Rahul, Sasisekharan, Ram

“…Heparin and heparan sulfate glycosaminoglycans (HSGAGs) comprise a chemically heterogeneous class of sulfated polysaccharides. The development of…”
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Heparin/Heparan Sulfate N-Sulfamidase from Flavobacterium heparinum by Myette, James R., Soundararajan, Venkataramanan, Behr, Jonathan, Shriver, Zachary, Raman, Rahul, Sasisekharan, Ram

“…Sulfated polysaccharides such as heparin and heparan sulfate glycosaminoglycans (HSGAGs) are chemically and structurally heterogeneous biopolymers that that…”
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Extrapolating from sequence-the 2009 H1N1 'swine' influenza virus by Sasisekharan, Ram, Soundararajan, Venkataramanan, Tharakaraman, Kannan, Raman, Rahul, Raguram, S, Shriver, Zachary, Sasisekharan, V

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The many faces of the YopM effector from plague causative bacterium Yersinia pestis and its implications for host immune modulation by Soundararajan, Venkataramanan, Patel, Neel, Subramanian, Vidya, Sasisekharan, Viswanathan, Sasisekharan, Ram

“…The Yersinia outer protein (Yop) M effector from the Yersinia pestis bacterium is well-known for being a critical virulence determinant; however, structural…”
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Networks link antigenic and receptor-binding sites of influenza hemagglutinin: Mechanistic insight into fitter strain propagation by Soundararajan, Venkataramanan, Zheng, Shu, Patel, Neel, Warnock, Ken, Raman, Rahul, Wilson, Ian A., Raguram, S., Sasisekharan, V., Sasisekharan, Ram

“…Influenza viral passaging through pre-vaccinated mice shows that emergent antigenic site mutations on the viral hemagglutinin (HA) impact host receptor-binding…”
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Corrigendum: Engineering and optimising deaminase fusions for genome editing by Yang, Luhan, Briggs, Adrian W, Chew, Wei Leong, Mali, Prashant, Guell, Marc, Aach, John, Goodman, Daniel Bryan, Cox, David, Kan, Yinan, Lesha, Emal, Soundararajan, Venkataramanan, Zhang, Feng, Church, George

“…This corrects the article DOI: 10.1038/ncomms13330…”
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Multifunctional Nanoscale Platforms for Targeting of the Cancer Cell Immortality Spectrum by Soundararajan, Venkataramanan, Warnock, Kenneth, Sasisekharan, Ram

“…In the post‐genomic era, “omics” platforms and cancer systems biology are greatly advancing our knowledge of the molecular and cellular underpinnings of…”
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Heparin/Heparan Sulfate 6-O-Sulfatase from Flavobacterium heparinum: INTEGRATED STRUCTURAL AND BIOCHEMICAL INVESTIGATION OF ENZYME ACTIVE SITE AND SUBSTRATE SPECIFICITY by Myette, James R, Soundararajan, Venkataramanan, Shriver, Zachary, Raman, Rahul, Sasisekharan, Ram

“…Heparin and heparan sulfate glycosaminoglycans (HSGAGs) comprise a chemically heterogeneous class of sulfated polysaccharides. The development of…”
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Heparin/heparan sulfate N-sulfamidase from Flavobacterium heparinum: structural and biochemical investigation of catalytic nitrogen-sulfur bond cleavage by Myette, James R, Soundararajan, Venkataramanan, Behr, Jonathan, Shriver, Zachary, Raman, Rahul, Sasisekharan, Ram

“…Sulfated polysaccharides such as heparin and heparan sulfate glycosaminoglycans (HSGAGs) are chemically and structurally heterogeneous biopolymers that that…”
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Multifunctional Nanoscale Platforms for Targeting of the Cancer Cell Immortality Spectrum: Multifunctional Micro- and Nanoparticles by SOUNDARARAJAN, Venkataramanan, WARNOCK, Kenneth, SASISEKHARAN, Ram

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Recombinant Expression, Purification, and Biochemical Characterization of Chondroitinase ABC II from Proteus vulgarisS by Prabhakar, Vikas, Capila, Ishan, Soundararajan, Venkataramanan, Raman, Rahul, Sasisekharan, Ram

“…Chondroitin lyases (or chondroitinases) are a family of enzymes that depolymerize chondroitin sulfate (CS) and dermatan sulfate (DS) galactosaminoglycans,…”
Get full text

A voxel-based Monte Carlo model of drug release from bulk eroding nanoparticles by Eavarone, David A, Soundararajan, Venkataramanan, Haller, Toomas, Sasisekharan, Ram

“…The use of polymeric nanoparticles as drug delivery devices is becoming increasingly prevalent in a variety of therapeutic applications. Despite their…”
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