Search Results - "Soulillou, J."

Unique B Cell Differentiation Profile in Tolerant Kidney Transplant Patients by Chesneau, M., Pallier, A., Braza, F., Lacombe, G., Le Gallou, S., Baron, D., Giral, M., Danger, R., Guerif, P., Aubert‐Wastiaux, H., Néel, A., Michel, L., Laplaud, D.‐A., Degauque, N., Soulillou, J.‐P., Tarte, K., Brouard, S.

“…Operationally tolerant patients (TOL) display a higher number of blood B cells and transcriptional B cell signature. As they rarely develop an allo‐immune…”
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Failure of Calcineurin Inhibitor (Tacrolimus) Weaning Randomized Trial in Long‐Term Stable Kidney Transplant Recipients by Dugast, E., Soulillou, J.‐P., Foucher, Y., Papuchon, E., Guerif, P., Paul, C., Riochet, D., Chesneau, M., Cesbron, A., Renaudin, K., Dantal, J., Giral, M., Brouard, S.

“…Long‐term renal transplant outcome is limited by side effects of immunosuppressive drugs, particularly calcineurin inhibitor (CNI). We assumed that some…”
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Posttransplant Donor‐Specific Anti‐HLA Antibodies Negatively Impact Pancreas Transplantation Outcome by Cantarovich, D., De Amicis, S., Akl, A., Devys, A., Vistoli, F., Karam, G., Soulillou, J.‐P.

“…During a 9‐year follow‐up, 167 consecutive pancreas transplant recipients (152 simultaneous pancreas‐kidney [SPK]) were followed for the detection of…”
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Multiparameter Immune Profiling of Operational Tolerance in Liver Transplantation by Martínez‐Llordella, M., Puig‐Pey, I, Orlando, G., Ramoni, M., Tisone, G., Rimola, A., Lerut, J., Latinne, D., Margarit, C., Bilbao, I., Brouard, S., Hernández‐Fuentes, M., Soulillou, J. ‐P., Sánchez‐Fueyo, A.

“…Immunosuppressive drugs can be completely withdrawn in up to 20% of liver transplant recipients, commonly referred to as ‘operationally’ tolerant. Immune…”
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Renal Operational Tolerance Is Associated With a Defect of Blood Tfh Cells That Exhibit Impaired B Cell Help by Chenouard, A., Chesneau, M., Bui Nguyen, L., Le Bot, S., Cadoux, M., Dugast, E., Paul, C., Malard‐Castagnet, S., Ville, S., Guérif, P., Soulillou, J.‐P., Degauque, N., Danger, R., Giral, M., Brouard, S.

“…Renal operationally tolerant patients (TOL) display a defect in B cell differentiation, with a deficiency in plasma cells. Recently described, T follicular…”
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The Natural History of Clinical Operational Tolerance After Kidney Transplantation Through Twenty‐Seven Cases by Brouard, S., Pallier, A., Renaudin, K., Foucher, Y., Danger, R., Devys, A., Cesbron, A., Guillot‐Guegen, C., Ashton‐Chess, J., Le Roux, S., Harb, J., Roussey, G., Subra, J.‐F., Villemain, F., Legendre, C., Bemelman, F.J., Orlando, G., Garnier, A., Jambon, H., Le Monies De Sagazan, H., Braun, L., Noël, C., Pillebout, E., Moal, M.‐C., Cantarell, C., Hoitsma, A., Ranbant, M., Testa, A., Soulillou, J.‐P., Giral, M.

“…We report here on a European cohort of 27 kidney transplant recipients displaying operational tolerance, compared to two cohorts of matched kidney transplant…”
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BAFF and BAFF‐R Levels Are Associated With Risk of Long‐Term Kidney Graft Dysfunction and Development of Donor‐Specific Antibodies by Thibault‐Espitia, A., Foucher, Y., Danger, R., Migone, T., Pallier, A., Castagnet, S., G.‐Gueguen, C., Devys, A., C.‐Gautier, A., Giral, M., Soulillou, J.‐P., Brouard, S.

“…There are lines of evidence that B cells may play a role in transplantation. B cell activating factor, BAFF, is a homotrimer that has been shown to play a role…”
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A Need for Biomarkers of Operational Tolerance in Liver and Kidney Transplantation by Londoño, M.‐C., Danger, R., Giral, M., Soulillou, J.‐P., Sánchez‐Fueyo, A., Brouard, S.

“…Both kidney and particularly liver recipients can occasionally discontinue all immunosuppressive drugs without undergoing rejection. These patients, who…”
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Clinical Operational Tolerance after Kidney Transplantation by Roussey‐Kesler, G., Giral, M., Moreau, A., Subra, J.‐F., Legendre, C., Noël, C., Pillebout, E., Brouard, S., Soulillou, J.‐P.

“…Induction of allograft‐specific tolerance and the detection of a “tolerance” state in recipients under immunosuppression with long‐term stable graft function…”
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Pretransplant Sensitization Against Angiotensin II Type 1 Receptor Is a Risk Factor for Acute Rejection and Graft Loss by Giral, M., Foucher, Y., Dufay, A., Van Huyen, J. P. D., Renaudin, K., Moreau, A., Philippe, A., Hegner, B., Dechend, R., Heidecke, H., Brouard, S., Cesbron, A., Castagnet, S., Devys, A., Soulillou, J. P., Dragun, D.

“…The angiotensin II type 1 receptor (AT1R) is an emerging target of functional non‐HLA antibodies (Ab). We examined the potential of determining the degree of…”
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Early Corticosteroid Avoidance in Kidney Transplant Recipients Receiving ATG‐F Induction: 5‐Year Actual Results of a Prospective and Randomized Study by Cantarovich, D., Rostaing, L., Kamar, N., Ducloux, D., Saint‐Hillier, Y., Mourad, G., Garrigue, V., Wolf, P., Ellero, B., Cassuto, E., Albano, L., Völp, A., Soulillou, J.‐P.

“…One hundred ninety‐seven patients received anti‐T‐lymphocyte globulins Fresenius, mycophenolate mofetil and delayed cyclosporine, and were randomized to…”
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Bortezomib, C1‐Inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi‐Transgenic GalT‐KO Pig Kidney Xenografts in Baboons by Le Bas‐Bernardet, S., Tillou, X., Branchereau, J., Dilek, N., Poirier, N., Châtelais, M., Charreau, B., Minault, D., Hervouet, J., Renaudin, K., Crossan, C., Scobie, L., Takeuchi, Y., Diswall, M., Breimer, M. E., Klar, N., Daha, M. R., Simioni, P., Robson, S. C., Nottle, M. B., Salvaris, E. J., Cowan, P. J., d'Apice, A. J. F., Sachs, D. H., Yamada, K., Lagutina, I., Duchi, R., Perota, A., Lazzari, G., Galli, C., Cozzi, E., Soulillou, J.‐P., Vanhove, B., Blancho, G.

“…Galactosyl‐transferase KO (GalT‐KO) pigs represent a potential solution to xenograft rejection, particularly in the context of additional genetic…”
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A tribute to Mohamed Daha by Soulillou, J.-P.

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B cells in operational tolerance by Chesneau, M., Danger, R., Soulillou, J.-P., Brouard, S.

“…Transplantation is currently the therapy of choice for endstage organ failure even though it requires long-term immunosuppresive therapy, with its numerous…”
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Decrease of blood anti-α1,3 Galactose Abs levels in multiple sclerosis (MS) and clinically isolated syndrome (CIS) patients by Le Berre, L, Rousse, J, Gourraud, P.-A, Imbert-Marcille, B.-M, Salama, A, Evanno, G, Semana, G, Nicot, A, Dugast, E, Guérif, P, Adjaoud, C, Freour, T, Brouard, S, Agbalika, F, Marignier, R, Brassat, D, Laplaud, D.-A, Drouet, E, Van Pesch, V, Soulillou, J.-P

“…Abstract The etiology of multiple sclerosis (MS) remains elusive. Among the possible causes, the increase of anti-Neu5Gc antibodies during EBV primo-infection…”
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Comparison of Transcriptional and Blood Cell‐Phenotypic Markers Between Operationally Tolerant Liver and Kidney Recipients by Lozano, J. J., Pallier, A., Martinez‐Llordella, M., Danger, R., López, M., Giral, M., Londoño, M. C., Rimola, A., Soulillou, J. P., Brouard, S., Sánchez‐Fueyo, A.

“…A proportion of transplant recipients can spontaneously accept their grafts in the absence of immunosuppression (operational tolerance). Previous studies…”
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Late Ureteral Stenosis Following Renal Transplantation: Risk Factors and Impact on Patient and Graft Survival by Karam, G., Hétet, J.‐F., Maillet, F., Rigaud, J., Hourmant, M., Soulillou, J.‐P., Giral, M.

“…The aim of this retrospective study of a cohort of 1787 consecutive kidney transplantations was to analyze the risk factors associated with the occurrence of…”
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Long‐Term Allograft Tolerance Is Characterized by the Accumulation of B Cells Exhibiting an Inhibited Profile by Le Texier, L., Thebault, P., Lavault, A., Usal, C., Merieau, E., Quillard, T., Charreau, B., Soulillou, J. P., Cuturi, M. C., Brouard, S., Chiffoleau, E.

“…Numerous reports have highlighted the central role of regulatory T cells in long‐term allograft tolerance, but few studies have investigated the B‐cell aspect…”
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Comparative Transcriptional and Phenotypic Peripheral Blood Analysis of Kidney Recipients Under Cyclosporin A or Sirolimus Monotherapy by Brouard, S., Puig‐Pey, I., Lozano, J.‐J., Pallier, A., Braud, C., Giral, M., Guillet, M., Londoño, M. C., Oppenheimer, F., Campistol, J. M., Soulillou, J.‐P., Sanchez‐Fueyo, A.

“…Due to its low level of nephrotoxicity and capacity to harness tolerogenic pathways, sirolimus (SRL) has been proposed as an alternative to calcineurin…”
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Humoral and Cellular Responses to Influenza Vaccination in Human Recipients Naturally Tolerant to a Kidney Allograft by Ballet, C., Roussey‐Kesler, G., Aubin, J.‐T., Brouard, S., Giral, M., Miqueu, P., Louis, S., Van Der Werf, S., Soulillou, J.‐P.

“…Rare kidney allograft recipients enjoy unaltered graft function years after interruption of their immunosuppressive treatment. To assess the extent to which…”
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