Search Results - "Soula, Cathy"

Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny by Romanos, Michèle, Allio, Guillaume, Roussigné, Myriam, Combres, Léa, Escalas, Nathalie, Soula, Cathy, Médevielle, François, Steventon, Benjamin, Trescases, Ariane, Bénazéraf, Bertrand

“…Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know little about its biological…”
Get full text

Moving the Shh Source over Time: What Impact on Neural Cell Diversification in the Developing Spinal Cord? by Danesin, Cathy, Soula, Cathy

“…A substantial amount of data has highlighted the crucial influence of Shh signalling on the generation of diverse classes of neurons and glial cells throughout…”
Get full text

Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord by Touahri, Yacine, Escalas, Nathalie, Benazeraf, Bertrand, Cochard, Philippe, Danesin, Cathy, Soula, Cathy

“…In the developing ventral spinal cord, motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) are sequentially generated from a common pool of neural…”
Get full text

Transcriptome profiling of the Olig2-expressing astrocyte subtype reveals their unique molecular signature by Ohayon, David, Aguirrebengoa, Marion, Escalas, Nathalie, Jungas, Thomas, Soula, Cathy

“…Astrocytes are recognized to be a heterogeneous population of cells that differ morphologically, functionally, and molecularly. Whether this heterogeneity…”
Get full text

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord by Danesin, Cathy, Darche-Gabinaud, Romain, Escalas, Nathalie, Bouguetoch, Vanessa, Cochard, Philippe, Al Oustah, Amir, Ohayon, David, Glise, Bruno, Soula, Cathy

“…Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates, a critical regulation level…”
Get full text

Dynamics of sonic hedgehog signaling in the ventral spinal cord are controlled by intrinsic changes in source cells requiring sulfatase 1 by Al Oustah, Amir, Danesin, Cathy, Khouri-Farah, Nagham, Farreny, Marie-Amélie, Escalas, Nathalie, Cochard, Philippe, Glise, Bruno, Soula, Cathy

“…In the ventral spinal cord, generation of neuronal and glial cell subtypes is controlled by Sonic hedgehog (Shh). This morphogen contributes to cell diversity…”
Get full text

Ventral Neural Progenitors Switch toward an Oligodendroglial Fate in Response to Increased Sonic Hedgehog (Shh) Activity: Involvement of Sulfatase 1 in Modulating Shh Signaling in the Ventral Spinal Cord by Danesin, Cathy, Agius, Eric, Escalas, Nathalie, Ai, Xingbin, Emerson, Charles, Cochard, Philippe, Soula, Cathy

“…In the embryonic chick ventral spinal cord, the initial emergence of oligodendrocytes is a relatively late event that depends on prolonged Sonic hedgehog (Shh)…”
Get full text

FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord by Farreny, Marie-Amélie, Agius, Eric, Bel-Vialar, Sophie, Escalas, Nathalie, Khouri-Farah, Nagham, Soukkarieh, Chadi, Danesin, Cathy, Pituello, Fabienne, Cochard, Philippe, Soula, Cathy

“…Most oligodendrocytes of the spinal cord originate from ventral progenitor cells of the pMN domain, characterized by expression of the transcription factor…”
Get full text

Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord by Laussu, Julien, Audouard, Christophe, Kischel, Anthony, Assis-Nascimento, Poincyane, Escalas, Nathalie, Liebl, Daniel J, Soula, Cathy, Davy, Alice

“…In the vertebrate spinal cord, motor neurons (MN) are generated in stereotypical numbers from a pool of dedicated progenitors (pMN) whose number depends on…”
Get full text

Neurogenic role of Gcm transcription factors is conserved in chicken spinal cord by Soustelle, Laurent, Trousse, Françoise, Jacques, Cécile, Ceron, Julian, Cochard, Philippe, Soula, Cathy, Giangrande, Angela

“…Although glial cells missing ( gcm ) genes are known as glial determinants in the fly embryo, the role of vertebrate orthologs in the central nervous system is…”
Get full text

Distinct sites of origin of oligodendrocytes and somatic motoneurons in the chick spinal cord: oligodendrocytes arise from Nkx2.2-expressing progenitors by a Shh-dependent mechanism by Soula, C, Danesin, C, Kan, P, Grob, M, Poncet, C, Cochard, P

“…In the vertebrate spinal cord, oligodendrocytes arise from the ventral part of the neuroepithelium, a region also known to generate somatic motoneurons. The…”
Get full text

Converse control of oligodendrocyte and astrocyte lineage development by Sonic hedgehog in the chick spinal cord by Agius, Eric, Soukkarieh, Chadi, Danesin, Cathy, Kan, Paulette, Takebayashi, Hirohide, Soula, Cathy, Cochard, Philippe

“…In the developing spinal cord, oligodendrocyte progenitors (OLPs) originate from the ventral neuroepithelium and the specification of this lineage depends on…”
Get full text

Expression analysis of Sulf1 in the chick forebrain at early and late stages of development by García‐López, Raquel, Soula, Cathy, Martínez, Salvador

“…Sulfatase 1 is a secreted enzyme that modulates the sulfation state of heparan sulfate proteoglycans (HSPGs), which are potential key regulators of diverse…”
Get full text

Sulfatase 2 promotes generation of a spinal cord astrocyte subtype that stands out through the expression of Olig2 by Ohayon, David, Escalas, Nathalie, Cochard, Philippe, Glise, Bruno, Danesin, Cathy, Soula, Cathy

“…Generation of glial cell diversity in the developing spinal cord is known to depend on spatio‐temporal patterning programs. In particular, expression of the…”
Get full text

DSulfatase-1 fine-tunes Hedgehog patterning activity through a novel regulatory feedback loop by Wojcinski, Alexandre, Nakato, Hiroshi, Soula, Cathy, Glise, Bruno

“…Sulfs are secreted sulfatases that catalyse removal of sulfate from Heparan Sulfate Proteoglycans (HSPGs) in the extracellular space. These enzymes are well…”
Get full text

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord by Danesin, Cathy, Darche-Gabinaud, Romain, Escalas, Nathalie, Bouguetoch, Vanessa, Cochard, Philippe, Al Oustah, Amir, Ohayon, David, Glise, Bruno, Soula, Cathy

“…Abstract Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates, a critical regulation…”
Get full text

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord by Arulkandarajah, Kalaimakan Hervé, Osterstock, Guillaume, Lafont, Agathe, Le Corronc, Hervé, Escalas, Nathalie, Corsini, Silvia, Le Bras, Barbara, Chenane, Linda, Boeri, Juliette, Czarnecki, Antonny, Mouffle, Christine, Bullier, Erika, Hong, Elim, Soula, Cathy, Legendre, Pascal, Mangin, Jean-Marie

“…In the developing central nervous system, electrical signaling is thought to rely exclusively on differentiating neurons as they acquire the ability to…”
Get full text

Role of BMPs in controlling the spatial and temporal origin of GFAP astrocytes in the embryonic spinal cord by Agius, Eric, Decker, Yann, Soukkarieh, Chadi, Soula, Cathy, Cochard, Philippe

“…In the vertebrate central nervous system (CNS), astrocytes are the most abundant and functionally diverse glial cell population. However, the mechanisms…”
Get full text

Pax2 regulates neuronal–glial cell fate choice in the embryonic optic nerve by Soukkarieh, Chadi, Agius, Eric, Soula, Cathy, Cochard, Philippe

“…During development, neural cell fate in the vertebrate optic nerve is restricted to the astroglial lineage. However, when isolated from the embryo and…”
Get full text

Induction of oligodendrocyte progenitors in the trunk neural tube by ventralizing signals: effects of notochord and floor plate grafts, and of sonic hedgehog by Poncet, Christian, Soula, Cathy, Trousse, Françoise, Kan, Paulette, Hirsinger, Estelle, Pourquié, Olivier, Duprat, Anne-Marie, Cochard, Philippe

“…Recent evidence indicates that oligodendrocytes originate initially from the ventral neural tube. We have documented in chick embryos the effect of early…”
Get full text