Search Results - "Soucy, Kyle"

Discovery and optimization of antibacterial AccC inhibitors by Cheng, Cliff C., Shipps, Gerald W., Yang, Zhiwei, Sun, Binyuan, Kawahata, Noriyuki, Soucy, Kyle A., Soriano, Aileen, Orth, Peter, Xiao, Li, Mann, Paul, Black, Todd

“…The biotin carboxylase (AccC) is part of the multi-component bacterial acetyl coenzyme-A carboxylase (ACCase) and is essential for pathogen survival. We…”
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Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B Polymerase by Cheng, Cliff C, Huang, Xiaohua, Shipps, Gerald W, Wang, Yu-Sen, Wyss, Daniel F, Soucy, Kyle A, Jiang, Chuan-kui, Agrawal, Sony, Ferrari, Eric, He, Zhiqing, Huang, H.-C

“…Pyridine carboxamide-based inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified and optimized to a variety of topologically related…”
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Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors by Huang, Xiaohua, Shipps, Gerald W., Cheng, Cliff C., Spacciapoli, Peter, Zhang, Xingmin, McCoy, Mark A., Wyss, Daniel F., Yang, Xianshu, Achab, Abdelghani, Soucy, Kyle, Montavon, Donna K., Murphy, Denise M., Whitehurst, Charles E.

“…A novel series of non-ATP-competitive MK2 inhibitors based on a furan-2-carboxyamide scaffold was discovered through high-throughput screening using the…”
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