Search Results - "Soubhi Smaili, Soraya"

α-Synuclein Interactions in Mitochondria-ER Contacts: A Possible Role in Parkinson's Disease by Erustes, Adolfo Garcia, Guarache, Gabriel Cicolin, Guedes, Erika da Cruz, Leão, Anderson Henrique França Figueredo, Pereira, Gustavo José da Silva, Smaili, Soraya Soubhi

“…Endoplasmic reticulum-mitochondria contact sites regulate various biological processes, such as mitochondrial dynamics, calcium homeostasis, autophagy and…”
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Calcium signaling alterations, oxidative stress, and autophagy in aging by Ureshino, Rodrigo Portes, Rocha, Katiucha Karolina, Lopes, Guiomar Silva, Bincoletto, Cláudia, Smaili, Soraya Soubhi

“…Aging is a multi-factorial process that may be associated with several functional and structural deficits which can evolve into degenerative diseases. In this…”
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Overexpression of α‐synuclein inhibits mitochondrial Ca2+ trafficking between the endoplasmic reticulum and mitochondria through MAMs by altering the GRP75–IP3R interaction by Erustes, Adolfo Garcia, D'Eletto, Manuela, Guarache, Gabriel Cicolin, Ureshino, Rodrigo Portes, Bincoletto, Claudia, Silva Pereira, Gustavo José, Piacentini, Mauro, Smaili, Soraya Soubhi

“…Mitochondria‐associated ER membranes (MAMs) are formed by close and specific components in the contact sites between the endoplasmic reticulum (ER) and…”
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Autophagy and intermittent fasting: the connection for cancer therapy? by Antunes, Fernanda, Erustes, Adolfo Garcia, Costa, Angélica Jardim, Nascimento, Ana Carolina, Bincoletto, Claudia, Ureshino, Rodrigo Portes, Pereira, Gustavo José Silva, Smaili, Soraya Soubhi

“…Cancer is a leading cause of death worldwide, and its incidence is continually increasing. Although anticancer therapy has improved significantly, it still has…”
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The Interplay between Ca2+ Signaling Pathways and Neurodegeneration by Ureshino, Rodrigo Portes, Erustes, Adolfo Garcia, Bassani, Taysa Bervian, Wachilewski, Patrícia, Guarache, Gabriel Cicolin, Nascimento, Ana Carolina, Costa, Angelica Jardim, Smaili, Soraya Soubhi, da Silva Pereira, Gustavo José

“…Calcium (Ca2+) homeostasis is essential for cell maintenance since this ion participates in many physiological processes. For example, the spatial and temporal…”
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Pharmacological Modulators of Autophagy as a Potential Strategy for the Treatment of COVID-19 by Pereira, Gustavo José da Silva, Leão, Anderson Henrique França Figueredo, Erustes, Adolfo Garcia, Morais, Ingrid Beatriz de Melo, Vrechi, Talita Aparecida de Moraes, Zamarioli, Lucas Dos Santos, Pereira, Cássia Arruda Souza, Marchioro, Laís de Oliveira, Sperandio, Letícia Paulino, Lins, Ísis Valeska Freire, Piacentini, Mauro, Fimia, Gian Maria, Reckziegel, Patrícia, Smaili, Soraya Soubhi, Bincoletto, Claudia

“…The family of coronaviruses (CoVs) uses the autophagy machinery of host cells to promote their growth and replication; thus, this process stands out as a…”
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NAADP-Evoked Ca2+ Signaling Leads to Mutant Huntingtin Aggregation and Autophagy Impairment in Murine Astrocytes by Pereira, Cássia Arruda de Souza, Medaglia, Natalia de Castro, Ureshino, Rodrigo Portes, Bincoletto, Claudia, Antonioli, Manuela, Fimia, Gian Maria, Piacentini, Mauro, Pereira, Gustavo José da Silva, Erustes, Adolfo Garcia, Smaili, Soraya Soubhi

“…Huntington’s disease (HD) is a progressive neurodegenerative disease characterized by mutations in the huntingtin gene (mHtt), causing an unstable repeat of…”
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FAM129A regulates autophagy in thyroid carcinomas in an oncogene-dependent manner by Nozima, Bruno Heidi, Mendes, Thais Biude, Pereira, Gustavo José da Silva, Araldi, Rodrigo Pinheiro, Iwamura, Edna Sadayo Miazato, Smaili, Soraya Soubhi, Carvalheira, Gianna Maria Griz, Cerutti, Janete Maria

“…We previously proposed that high expression of FAM129A can be used as a thyroid carcinoma biomarker in preoperative diagnostic exams of thyroid nodules. Here,…”
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17β‐estradiol reduces SARS‐CoV‐2 infection in vitro by Lemes, Robertha Mariana Rodrigues, Costa, Angelica Jardim, Bartolomeo, Cynthia Silva, Bassani, Taysa Bervian, Nishino, Michelle Sayuri, Pereira, Gustavo Jose da Silva, Smaili, Soraya Soubhi, Maciel, Rui Monteiro de Barros, Braconi, Carla Torres, da Cruz, Edgar Ferreira, Ramirez, Ana Lopez, Maricatto, Juliana Terzi, Janini, Luiz Mario Ramos, Prado, Carla Máximo, Stilhano, Roberta Sessa, Ureshino, Rodrigo Portes

“…The COVID‐19 has originated from Wuhan, China, in December 2019 and has been affecting the public health system, society, and economy in an unheard‐of manner…”
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Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor by Stilhano, Roberta Sessa, Samoto, Vivian Yochiko, Silva, Leonardo Martins, Pereira, Gustavo José, Erustes, Adolfo Garcia, Smaili, Soraya Soubhi, Won Han, Sang

“…Regeneration of injured skeletal muscles is affected by fibrosis, which can be improved by the administration of angiotensin II (AngII) receptor (ATR) blockers…”
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Effects of Aging in the Striatum and Substantia Nigra of a Parkinson’s Disease Animal Model by Ureshino, Rodrigo Portes, Costa, Angelica Jardim, Erustes, Adolfo Garcia, Pereira, Gustavo José da Silva, Sinigaglia-Coimbra, Rita, Smaili, Soraya Soubhi

“…Aging is a multifactorial process associated with functional deficits, and the brain is more prone to developing chronic degenerative diseases such as…”
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Lack of Autophagy Induction by Lithium Decreases Neuroprotective Effects in the Striatum of Aged Rats by Costa, Angelica Jardim, Erustes, Adolfo Garcia, Sinigaglia, Rita, Girardi, Carlos Eduardo Neves, Pereira, Gustavo José da Silva, Ureshino, Rodrigo Portes, Smaili, Soraya Soubhi

“…The pharmacological modulation of autophagy is considered a promising neuroprotective strategy. While it has been postulated that lithium regulates this…”
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The phosphorylation status and cytoskeletal remodeling of striatal astrocytes treated with quinolinic acid by Pierozan, Paula, Ferreira, Fernanda, Ortiz de Lima, Bárbara, Gonçalves Fernandes, Carolina, Totarelli Monteforte, Priscila, de Castro Medaglia, Natalia, Bincoletto, Claudia, Soubhi Smaili, Soraya, Pessoa-Pureur, Regina

“…Quinolinic acid (QUIN) is a glutamate agonist which markedly enhances the vulnerability of neural cells to excitotoxicity. QUIN is produced from the amino acid…”
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PHYTOCHEMICAL ANALYSIS OF HYDROETHANOLIC EXTRACTS FROM POWDERED ROOTS OF Panax ginseng C. A. Meyer AND Heteropterys tomentosa A. Juss AND EVALUATION OF THEIR EFFECTS ON ASTROCYTE CELL DEATH by Bezerra, Andréia Gomes, Negri, Giuseppina, Duarte-Almeida, Joaquim Maurício, Smaili, Soraya Soubhi, Carlini, Elisaldo Araújo

“…The medicinal plants Panax ginseng C. A. Meyer (Araliaceae) and Heteropterys tomentosa A. Juss (Malpighiaceae) are widely and separately used by the Brazilian…”
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Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress by Antunes, Fernanda, Pereira, Gustavo J S, Saito, Renata F, Buri, Marcus V, Gagliardi, Mara, Bincoletto, Claudia, Chammas, Roger, Fimia, Gian Maria, Piacentini, Mauro, Corazzari, Marco, Smaili, Soraya Soubhi

“…Skin melanoma is one of the most aggressive and difficult-to-treat human malignancies, characterized by poor survival rates, thus requiring urgent novel…”
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Effects of ICI 182,780, an ERα and ERβ antagonist, and G-1, a GPER agonist, on autophagy in breast cancer cells by Muler, Mari Luminosa, Antunes, Fernanda, Guarache, Gabriel Cicolin, Oliveira, Rafaela Brito, Ureshino, Rodrigo Portes, Bincoletto, Claudia, Pereira, Gustavo José da Silva, Smaili, Soraya Soubhi

“…To investigate if ICI 182,780 (fulvestrant), a selective estrogen receptor alpha/beta (ERα/ERβ) antagonist, and G-1, a selective G-protein-coupled receptor…”
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Bothrops leucurus venom induces nephrotoxicity in the isolated perfused kidney and cultured renal tubular epithelia by de Morais, Isabel Cristina Oliveira, Torres, Alba Fabíola Costa, Pereira, Gustavo José da Silva, Pereira, Ticiana Praciano, Pessoa Bezerra de Menezes, Ramon Róseo de Paula, Mello, Clarissa Perdigão, Coelho Jorge, Antonio Rafael, Bindá, Alexandre Havt, Toyama, Marcos Hikari, Monteiro, Helena Serra Azul, Smaili, Soraya Soubhi, Martins, Alice Maria Costa

“…Bites from snake (Bothrops genus) cause local tissue damage and systemic complications, which include alterations such as hemostatic system and acute renal…”
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Phytochemical analysis of hydroethanolic extract of Turnera diffusa Willd and evaluation of its effects on astrocyte cell death by Bezerra, Andréia Gomes, Negri, Giuseppina, Duarte-Almeida, Joaquim Maurício, Smaili, Soraya Soubhi, Carlini, Elisaldo Araújo

“…To evaluate the phytochemical composition of hydroethanolic extracts from powdered aerial parts of Turnera diffusa Willd (Turneraceae; T. diffusa), as well as…”
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Changes of cytosolic calcium and contractility of young rat vas deferens by acute treatment with amphetamine, fluoxetine or sibutramine by Hyppolito Jurkiewicz, Neide, da Silva Júnior, Edilson Dantas, de Souza, Bruno Palmieri, Ferreira Verde, Luciana, Drawanz Pereira, Janaina, Mendes Sobrinho, Cairo, Soubhi Smaili, Soraya, Caricati-Neto, Afonso, Miranda-Ferreira, Regiane, Jurkiewicz, Aron

“…Previous studies conducted in our laboratory indicated that administration of amphetamine, fluoxetine or sibutramine affects the sympathetic nervous system of…”
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Effects of Panax ginseng, Turnera diffusa and Heteropterys tomentosa extracts on hippocampal apoptosis of aged rats by Bezerra, Andréia Gomes, Smaili, Soraya Soubhi, Lopes, Guiomar Silva, Carlini, Elisaldo Araújo

“…To verify if the medicinal plants Panax ginseng C.A. Mey, Turnera diffusa Willd. ex Schult., and Heteropterys tomentosa O. Mach., which are amply used by the…”
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