Search Results - "Sottile, Virginie"

Caffeine exposure induces browning features in adipose tissue in vitro and in vivo by Velickovic, Ksenija, Wayne, Declan, Leija, Hilda Anaid Lugo, Bloor, Ian, Morris, David E., Law, James, Budge, Helen, Sacks, Harold, Symonds, Michael E., Sottile, Virginie

“…Brown adipose tissue (BAT) is able to rapidly generate heat and metabolise macronutrients, such as glucose and lipids, through activation of mitochondrial…”
Get full text

Impact of Serum Source on Human Mesenchymal Stem Cell Osteogenic Differentiation in Culture by Popov, Alexander, Scotchford, Colin, Grant, David, Sottile, Virginie

“…Human mesenchymal stem cells (MSCs) show promise for musculoskeletal repair applications. Animal-derived serum is extensively used for MSC culture as a source…”
Get full text

chick embryo: hatching a model for contemporary biomedical research by Rashidi, Hassan, Sottile, Virginie

“…Animal models play a crucial role in fundamental and medical research. Progress in the fields of drug discovery, regenerative medicine and cancer research…”
Get full text

Stilbene Treatment Reduces Stemness Features in Human Lung Adenocarcinoma Model by Livraghi, Vittoria, Grossi, Alice, Scopelliti, Anna, Senise, Giorgia, Gamboa, Luciano Augusto, Solito, Samantha, Stivala, Lucia Anna, Sottile, Virginie, Savio, Monica

“…Lung cancer is among the most clinically challenging tumors because of its aggressive proliferation, metastasis, and the presence of cancer stem cells (CSCs)…”
Get full text

Integrated Multi-Assay Culture Model for Stem Cell Chondrogenic Differentiation by Prosser, Amy, Scotchford, Colin, Roberts, George, Grant, David, Sottile, Virginie

“…Recent osteochondral repair strategies highlight the promise of mesenchymal progenitors, an accessible stem cell source with osteogenic and chondrogenic…”
Get full text

Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro by Velickovic, Ksenija, Lugo Leija, Hilda Anaid, Bloor, Ian, Law, James, Sacks, Harold, Symonds, Michael, Sottile, Virginie

“…Brown and beige adipocytes are characterised as expressing the unique mitochondrial uncoupling protein (UCP)1 for which the primary stimulus in vivo is cold…”
Get full text

Leptin deficiency impairs adipogenesis and browning response in mouse mesenchymal progenitors by Velickovic, Ksenija, Leija, Hilda Anaid Lugo, Kosic, Bojana, Sacks, Harold, Symonds, Michael E., Sottile, Virginie

“…Although phenotypically different, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) are able to produce heat through non-shivering…”
Get full text

Cytoplasmic RNA in Undifferentiated Neural Stem Cells: A Potential Label-Free Raman Spectral Marker for Assessing the Undifferentiated Status by Ghita, Adrian, Pascut, Flavius C, Mather, Melissa, Sottile, Virginie, Notingher, Ioan

“…Raman microspectroscopy (rms) was used to identify, image, and quantify potential molecular markers for label-free monitoring the differentiation status of…”
Get full text

Osteogenic Response of Human Mesenchymal Stem Cells Analysed Using Combined Intracellular and Extracellular Metabolomic Monitoring by Surrati, Amal, Evseev, Sergey, Jourdan, Fabien, Kim, Dong-Hyun, Sottile, Virginie

“…Background/Aims: The skeleton is a metabolically active organ undergoing continuous remodelling initiated by mesenchymal progenitors present in bone and bone…”
Get full text

Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro by Nizamudeen, Zubair Ahmed, Chakrabarti, Lisa, Sottile, Virginie

“…Fasudil is a clinically approved Rho-associated protein kinase (ROCK) inhibitor that has been used widely to treat cerebral consequences of subarachnoid…”
Get full text

Dynamic distribution and stem cell characteristics of Sox1-expressing cells in the cerebellar cortex by Alcock, Joelle, Sottile, Virginie

“…Bergmann glia cells are a discrete radial glia population surrounding Purkinje cells in the cerebellar cortex. Although Bergmann glia are essential for the…”
Get full text

Performance of multiphase scaffolds for bone repair based on two-photon polymerized poly(d,l-lactide-co-ɛ-caprolactone), recombinamers hydrogel and nano-HA by Felfel, Reda M., Gupta, Dhanak, Zabidi, Adi Z., Prosser, Amy, Scotchford, Colin A., Sottile, Virginie, Grant, David M.

“…Multiphase hybrids were fabricated from poly(d,l-lactide-co-ɛ-caprolactone) (PLCL) copolymer scaffolds impregnated with silk-elastin-like recombinamers (SELRs)…”
Get full text

Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties by Nizamudeen, Zubair Ahmed, Xerri, Rachael, Parmenter, Christopher, Suain, Kiran, Markus, Robert, Chakrabarti, Lisa, Sottile, Virginie

“…Low-power sonication is widely used to disaggregate extracellular vesicles (EVs) after isolation, however, the effects of sonication on EV samples beyond…”
Get full text

Tailoring Pyro-and Orthophosphate Species to Enhance Stem Cell Adhesion to Phosphate Glasses by De Melo, Nigel, Murrell, Lauren, Islam, Md Towhidul, Titman, Jeremy J, Macri-Pellizzeri, Laura, Ahmed, Ifty, Sottile, Virginie

“…Phosphate-based glasses (PBGs) offer significant therapeutic potential due to their bioactivity, controllable compositions, and degradation rates. Several PBGs…”
Get full text

Magnetically Assisted Control of Stem Cells Applied in 2D, 3D and In Situ Models of Cell Migration by Harrison, Richard, Luckett, Jeni, Marsh, Sarah, Lugo Leija, Hilda Anaid, Salih, Shelanah, Alkharji, Reem, Sottile, Virginie

“…The success of cell therapy approaches is greatly dependent on the ability to precisely deliver and monitor transplanted stem cell grafts at treated sites…”
Get full text

Bone marrow as a source of stem cells and germ cells? Perspectives for transplantation by Sottile, Virginie

“…Recent publications have suggested the existence of germ stem cells in the mouse at postnatal stages. The mechanism of de novo oocyte formation is proposed to…”
Get full text

Transient Accumulation of 5-Carboxylcytosine Indicates Involvement of Active Demethylation in Lineage Specification of Neural Stem Cells by Wheldon, Lee M., Abakir, Abdulkadir, Ferjentsik, Zoltan, Dudnakova, Tatiana, Strohbuecker, Stephanie, Christie, Denise, Dai, Nan, Guan, Shengxi, Foster, Jeremy M., Corrêa, Ivan R., Loose, Matthew, Dixon, James E., Sottile, Virginie, Johnson, Andrew D., Ruzov, Alexey

“…5-Methylcytosine (5mC) is an epigenetic modification involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to…”
Get full text

Towards quantitative molecular mapping of cells by Raman microscopy: using AFM for decoupling molecular concentration and cell topography by Boitor, Radu, Sinjab, Faris, Strohbuecker, Stephanie, Sottile, Virginie, Notingher, Ioan

“…Raman micro-spectroscopy (RMS) is a non-invasive technique for imaging live cells in vitro. However, obtaining quantitative molecular information from Raman…”
Get more information

Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy by Ghita, Adrian, Pascut, Flavius C, Sottile, Virginie, Notingher, Ioan

“…Raman microscopy was used as a label-free method to study the mineralisation of bone nodules formed by mesenchymal stem cells cultured in osteogenic medium in…”
Get more information

In Silico Identification of SOX1 Post-Translational Modifications Highlights a Shared Protein Motif by Ahmad, Azaz, Strohbuecker, Stephanie, Scotti, Claudia, Tufarelli, Cristina, Sottile, Virginie

“…The transcription factor SOX1 is a key regulator of neural stem cell development, acting to keep neural stem cells (NSCs) in an undifferentiated state…”
Get full text