Search Results - "Sottile, Peter D"
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The Association Between Ventilator Dyssynchrony, Delivered Tidal Volume, and Sedation Using a Novel Automated Ventilator Dyssynchrony Detection Algorithm
Published in Critical care medicine (01-02-2018)“…Ventilator dyssynchrony is potentially harmful to patients with or at risk for the acute respiratory distress syndrome. Automated detection of ventilator…”
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Neuromuscular blockade is associated with the attenuation of biomarkers of epithelial and endothelial injury in patients with moderate-to-severe acute respiratory distress syndrome
Published in Critical care (London, England) (10-03-2018)“…Neuromuscular blockade (NMB) is a therapy for acute respiratory distress syndrome (ARDS). However, the mechanism by which NMB may improve outcome for ARDS…”
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3
Association Between Resilience and Family Member Psychologic Symptoms in Critical Illness
Published in Critical care medicine (01-08-2016)“…OBJECTIVES:There are increased rates of depression, anxiety, and stress disorders in families of critically ill patients. Interventions directed at family…”
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Differential effects of two-hit models of acute and ventilator-induced lung injury on lung structure, function, and inflammation
Published in Frontiers in physiology (26-07-2023)“…Acute respiratory distress syndrome (ARDS) and acute lung injury have a diverse spectrum of causative factors including sepsis, aspiration of gastric contents,…”
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A Damaged-Informed Lung Ventilator Model for Ventilator Waveforms
Published in Frontiers in physiology (01-10-2021)“…Motivated by a desire to understand pulmonary physiology, scientists have developed physiological lung models of varying complexity. However, pathophysiology…”
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Patterns of utilization and effects of hospital-specific factors on physical, occupational, and speech therapy for critically ill patients with acute respiratory failure in the USA: results of a 5-year sample
Published in Critical care (London, England) (16-05-2019)“…Timely initiation of physical, occupational, and speech therapy in critically ill patients is crucial to reduce morbidity and improve outcomes. Over a 5-year…”
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Ventilator dyssynchrony - Detection, pathophysiology, and clinical relevance: A Narrative review
Published in Annals of thoracic medicine (01-10-2020)“…Mortality associated with the acute respiratory distress syndrome remains unacceptably high due in part to ventilator-induced lung injury (VILI). Ventilator…”
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Patient and family perceptions of physical therapy in the medical intensive care unit
Published in Journal of critical care (01-10-2015)“…Abstract Purpose Patient and family member perceptions of physical therapy (PT) in the intensive care unit and the factors that influence their degree of…”
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Significant Variability in Surrogate Informed Consent Rates in ARDS and Prevention and Early Treatment of Acute Lung Injury Network Multicenter Trials
Published in Chest (01-05-2022)Get full text
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Flow-Limited and Reverse-Triggered Ventilator Dyssynchrony Are Associated With Increased Tidal and Dynamic Transpulmonary Pressure
Published in Critical care medicine (01-05-2024)“…Ventilator dyssynchrony may be associated with increased delivered tidal volumes (V t s) and dynamic transpulmonary pressure (ΔP L,dyn ), surrogate markers of…”
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Myorelaxants in ARDS patients
Published in Intensive care medicine (01-12-2020)“…Neuromuscular blocking agents (NMBAs) inhibit patient-initiated active breath and the risk of high tidal volumes and consequent high transpulmonary pressure…”
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An Observational Study of the Efficacy of Cisatracurium Compared with Vecuronium in Patients with or at Risk for Acute Respiratory Distress Syndrome
Published in American journal of respiratory and critical care medicine (01-04-2018)“…The neuromuscular blocking agent cisatracurium may improve mortality for patients with moderate-to-severe acute respiratory distress syndrome (ARDS). Other…”
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The Importance of Coping in Critically Ill Patients
Published in Critical care medicine (01-09-2016)Get full text
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Surrogate Decision Makers' Interpretation of Prognostic Information: A Mixed-Methods Study
Published in Annals of internal medicine (06-03-2012)“…Little is known about why surrogate decision makers for patients with advanced illness often have overly optimistic expectations about prognosis. To determine…”
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Quantifiable identification of flow-limited ventilator dyssynchrony with the deformed lung ventilator model
Published in Computers in biology and medicine (01-05-2024)“…Ventilator dyssynchrony (VD) can worsen lung injury and is challenging to detect and quantify due to the complex variability in the dyssynchronous breaths…”
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Hypothesis-driven modeling of the human lung–ventilator system: A characterization tool for Acute Respiratory Distress Syndrome research
Published in Journal of biomedical informatics (01-01-2023)“…Mechanical ventilation is an essential tool in the management of Acute Respiratory Distress Syndrome (ARDS), but it exposes patients to the risk of…”
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Analgesia and Sedation Use During Noninvasive Ventilation for Acute Respiratory Failure
Published in Critical care medicine (01-07-2024)“…To describe U.S. practice regarding administration of sedation and analgesia to patients on noninvasive ventilation (NIV) for acute respiratory failure (ARF)…”
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Ethical Triage Demands a Better Triage Survivability Score
Published in American journal of bioethics (02-07-2020)Get full text
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Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure
Published in Chest (01-01-2023)“…Asthma exacerbations with respiratory failure (AERF) are associated with hospital mortality of 7% to 15%. Extracorporeal membrane oxygenation (ECMO) has been…”
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Clinical informatics accelerates health system adaptation to the COVID-19 pandemic: examples from Colorado
Published in Journal of the American Medical Informatics Association : JAMIA (09-12-2020)“…Abstract Objective Large health systems responding to the coronavirus disease 2019 (COVID-19) pandemic face a broad range of challenges; we describe 14…”
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