Search Results - "Sotirchos, Elias S"

DeepHarmony: A deep learning approach to contrast harmonization across scanner changes by Dewey, Blake E., Zhao, Can, Reinhold, Jacob C., Carass, Aaron, Fitzgerald, Kathryn C., Sotirchos, Elias S., Saidha, Shiv, Oh, Jiwon, Pham, Dzung L., Calabresi, Peter A., van Zijl, Peter C.M., Prince, Jerry L.

“…Magnetic resonance imaging (MRI) is a flexible medical imaging modality that often lacks reproducibility between protocols and scanners. It has been shown that…”
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Aquaporin-4 IgG seropositivity is associated with worse visual outcomes after optic neuritis than MOG-IgG seropositivity and multiple sclerosis, independent of macular ganglion cell layer thinning by Sotirchos, Elias S, Filippatou, Angeliki, Fitzgerald, Kathryn C, Salama, Sara, Pardo, Santiago, Wang, Jiangxia, Ogbuokiri, Esther, Cowley, Norah J, Pellegrini, Nicole, Murphy, Olwen C, Mealy, Maureen A, Prince, Jerry L, Levy, Michael, Calabresi, Peter A, Saidha, Shiv

“…Background: Comparative studies of characteristics of optic neuritis (ON) associated with myelin oligodendrocyte glycoprotein-IgG (MOG-ON) and aquaporin-4-IgG…”
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Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis by Sotirchos, Elias S, Bhargava, Pavan, Eckstein, Christopher, Van Haren, Keith, Baynes, Moira, Ntranos, Achilles, Gocke, Anne, Steinman, Lawrence, Mowry, Ellen M, Calabresi, Peter A

“…OBJECTIVE:To study the safety profile and characterize the immunologic effects of high- vs low-dose cholecalciferol supplementation in patients with multiple…”
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AQP4-IgG and MOG-IgG Related Optic Neuritis—Prevalence, Optical Coherence Tomography Findings, and Visual Outcomes: A Systematic Review and Meta-Analysis by Filippatou, Angeliki G., Mukharesh, Loulwah, Saidha, Shiv, Calabresi, Peter A., Sotirchos, Elias S.

“…Background: Optic neuritis (ON) is a cardinal manifestation of multiple sclerosis (MS), aquaporin-4 (AQP4)-IgG-, and myelin oligodendrocyte glycoprotein…”
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Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study by Saidha, Shiv, Dr, Sotirchos, Elias S, MD, Ibrahim, Mohamed A, MD, Crainiceanu, Ciprian M, PhD, Gelfand, Jeffrey M, MD, Sepah, Yasir J, MBBS, Ratchford, John N, MD, Oh, Jiwon, FRCPC, Seigo, Michaela A, ScB, Newsome, Scott D, DO, Balcer, Laura J, Prof, Frohman, Elliot M, Prof, Green, Ari J, MD, Nguyen, Quan D, MD, Calabresi, Peter A, Prof

“…Summary Background Microcystic macular oedema (MMO) of the retinal inner nuclear layer (INL) has been identified in patients with multiple sclerosis (MS) by…”
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OCT is an alternative to MRI for monitoring MS – YES by Sotirchos, Elias S, Saidha, Shiv

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Retinal layer segmentation of macular OCT images using boundary classification by Lang, Andrew, Carass, Aaron, Hauser, Matthew, Sotirchos, Elias S, Calabresi, Peter A, Ying, Howard S, Prince, Jerry L

“…Optical coherence tomography (OCT) has proven to be an essential imaging modality for ophthalmology and is proving to be very important in neurology. OCT…”
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Alterations in the retinal vasculature occur in multiple sclerosis and exhibit novel correlations with disability and visual function measures by Murphy, Olwen C, Kwakyi, Ohemaa, Iftikhar, Mustafa, Zafar, Sidra, Lambe, Jeffrey, Pellegrini, Nicole, Sotirchos, Elias S, Gonzalez-Caldito, Natalia, Ogbuokiri, Esther, Filippatou, Angeliki, Risher, Hunter, Cowley, Norah, Feldman, Sydney, Fioravante, Nicholas, Frohman, Elliot M, Frohman, Teresa C, Balcer, Laura J, Prince, Jerry L, Channa, Roomasa, Calabresi, Peter A, Saidha, Shiv

“…Background: The retinal vasculature may be altered in multiple sclerosis (MS), potentially acting as a biomarker of disease processes. Objective: To compare…”
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Longitudinal evaluation of serum MOG-IgG titers in MOGAD after initiation of maintenance immunoglobulin: A case series by Roy, Shuvro, Vasileiou, Eleni, Barreras, Paula, Ahmadi, Gelareh, Chen, Haiwen, Suslovic, William, Kornbluh, Alexandra, Kahn, Ilana, Sotirchos, Elias S

“…Background: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a distinct demyelinating disease of the central nervous system…”
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Serum ceramide levels are altered in multiple sclerosis by Filippatou, Angeliki G, Moniruzzaman, Mohammed, Sotirchos, Elias S, Fitzgerald, Kathryn C, Kalaitzidis, Grigorios, Lambe, Jeffrey, Vasileiou, Eleni, Saidha, Shiv, Prince, Jerry L, Haughey, Norman, Calabresi, Peter A, Bhargava, Pavan

“…Background: Sphingolipids are myelin components and inflammatory signaling intermediates. Sphingolipid metabolism may be altered in people with multiple…”
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Evidence of subclinical quantitative retinal layer abnormalities in AQP4-IgG seropositive NMOSD by Filippatou, Angeliki G, Vasileiou, Eleni S, He, Yufan, Fitzgerald, Kathryn C, Kalaitzidis, Grigorios, Lambe, Jeffrey, Mealy, Maureen A, Levy, Michael, Liu, Yihao, Prince, Jerry L, Mowry, Ellen M, Saidha, Shiv, Calabresi, Peter A, Sotirchos, Elias S

“…Background: Prior studies have suggested that subclinical retinal abnormalities may be present in aquaporin-4 immunoglobulin G (AQP4-IgG) seropositive…”
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Effect of disease-modifying therapies on subcortical gray matter atrophy in multiple sclerosis by Sotirchos, Elias S, Gonzalez-Caldito, Natalia, Dewey, Blake E, Fitzgerald, Kathryn C, Glaister, Jeffrey, Filippatou, Angeliki, Ogbuokiri, Esther, Feldman, Sydney, Kwakyi, Ohemaa, Risher, Hunter, Crainiceanu, Ciprian, Pham, Dzung L, Van Zijl, Peter C, Mowry, Ellen M, Reich, Daniel S, Prince, Jerry L, Calabresi, Peter A, Saidha, Shiv

“…Background: The effects of disease-modifying therapies (DMTs) on region-specific brain atrophy in multiple sclerosis (MS) are unclear. Objective: To determine…”
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Mitochondrial measures in neuronally enriched extracellular vesicles predict brain and retinal atrophy in multiple sclerosis by Ladakis, Dimitrios C, Yao, Pamela J, Vreones, Michael, Blommer, Joseph, Kalaitzidis, Grigorios, Sotirchos, Elias S, Fitzgerald, Kathryn C, Saidha, Shiv, Calabresi, Peter A, Kapogiannis, Dimitrios, Bhargava, Pavan

“…Background: Mitochondrial dysfunction plays an important role in multiple sclerosis (MS) disease progression. Plasma extracellular vesicles are a potential…”
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The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives by Gharagozloo, Marjan, Galleguillos, Danny, Jank, Larissa, Sotirchos, Elias S., Smith, Matthew D., Garton, Thomas, Kumar, Swati, Hussein, Omar, Potluri, Saahith, Taylor, Michelle, Siu, Catherine, Mace, Jackson W., Dawson, Ted, Dawson, Valina L., Lee, Seulki, Calabresi, Peter A.

“…Recent evidence suggests that the glucagon-like peptide-1 receptor (GLP-1R) agonists have neuroprotective activities in the CNS in animal models of Parkinson's…”
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In vivo identification of morphologic retinal abnormalities in neuromyelitis optica by SOTIRCHOS, Elias S, SAIDHA, Shiv, CRAINICEANU, Ciprian M, QUAN DONG NGUYEN, LEVY, Michael, CALABRESI, Peter A, BYRAIAH, Gita, MEALY, Maureen A, IBRAHIM, Mohamed A, SEPAH, Yasir Jamal, NEWSOME, Scott D, RATCHFORD, John N, FROHMAN, Elliot M, BALCER, Laura J

“…To assess eyes with neuromyelitis optica (NMO) for morphologic retinal abnormalities utilizing high-definition optical coherence tomography (OCT) imaging. In…”
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Therapeutic Potential of a Novel Glucagon-like Peptide-1 Receptor Agonist, NLY01, in Experimental Autoimmune Encephalomyelitis by Gharagozloo, Marjan, Smith, Matthew D., Sotirchos, Elias S., Jin, Jing, Meyers, Keya, Taylor, Michelle, Garton, Thomas, Bannon, Riley, Lord, Hannah-Noelle, Dawson, Ted M., Dawson, Valina L., Lee, Seulki, Calabresi, Peter A.

“…Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), characterized by demyelination, gliosis, and neurodegeneration…”
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A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis by Daboul, Lynn, O’Donnell, Carly M, Amin, Moein, Rodrigues, Paulo, Derbyshire, John, Azevedo, Christina, Bar-Or, Amit, Caverzasi, Eduardo, Calabresi, Peter A, Cree, Bruce AC, Freeman, Leorah, Henry, Roland G, Longbrake, Erin E, Oh, Jiwon, Papinutto, Nico, Pelletier, Daniel, Prchkovska, Vesna, Raza, Praneeta, Ramos, Marc, Samudralwar, Rohini D, Schindler, Matthew K, Sotirchos, Elias S, Sicotte, Nancy L, Solomon, Andrew J, Shinohara, Russell T, Reich, Daniel S, Sati, Pascal, Ontaneda, Daniel

“…Background: The central vein sign (CVS) is a proposed magnetic resonance imaging (MRI) biomarker for multiple sclerosis (MS); the optimal method for…”
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Association of body mass index with longitudinal rates of retinal atrophy in multiple sclerosis by Filippatou, Angeliki G, Lambe, Jeffrey, Sotirchos, Elias S, Fitzgerald, Kathryn C, Aston, Andrew, Murphy, Olwen C, Pellegrini, Nicole, Fioravante, Nicholas, Risher, Hunter, Ogbuokiri, Esther, Kwakyi, Ohemaa, Toliver, Brandon, Davis, Simidele, Luciano, Nicholas, Crainiceanu, Ciprian, Prince, Jerry L, Mowry, Ellen M, Calabresi, Peter A, Saidha, Shiv

“…Background: Studies evaluating associations between body mass index (BMI) and optical coherence tomography (OCT) measures in multiple sclerosis (MS) are…”
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Diagnostic performance of central vein sign versus oligoclonal bands for multiple sclerosis by Toljan, Karlo, Daboul, Lynn, Raza, Praneeta, Martin, Melissa L, Cao, Quy, O’Donnell, Carly M, Rodrigues, Paulo, Derbyshire, John, Azevedo, Christina J, Bar-Or, Amit, Caverzasi, Eduardo, Calabresi, Peter A, Cree, Bruce AC, Freeman, Leorah, Henry, Roland G, Longbrake, Erin E, Oh, Jiwon, Papinutto, Nico, Pelletier, Daniel, Samudralwar, Rohini D, Schindler, Matthew K, Sotirchos, Elias S, Sicotte, Nancy L, Solomon, Andrew J, Shinohara, Russell T, Reich, Daniel S, Sati, Pascal, Ontaneda, Daniel

“…Background: Cerebrospinal fluid (CSF) oligoclonal bands (OCB) are a diagnostic biomarker in multiple sclerosis (MS). The central vein sign (CVS) is an imaging…”
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Spinal cord and infratentorial lesions in radiologically isolated syndrome are associated with decreased retinal ganglion cell/inner plexiform layer thickness by Filippatou, Angeliki, Shoemaker, Thomas, Esch, Megan, Qutab, Madiha, Gonzalez-Caldito, Natalia, Prince, Jerry L, Mowry, Ellen M, Calabresi, Peter A, Saidha, Shiv, Sotirchos, Elias S

“…Background: The role of retinal imaging with optical coherence tomography (OCT) in assessing individuals with radiologically isolated syndrome (RIS) remains…”
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