Search Results - "Sote M. Vladimirov"
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A PAMPA assay as fast predictive model of passive human skin permeability of new synthesized corticosteroid C-21 esters
Published in Molecules (Basel, Switzerland) (05-01-2012)“…The permeation properties of twenty newly synthesized α-alkoxyalkanoyl and α-aryloxyalkanoyl C-21 esters of standard corticosteroids: Fluocinolone acetonide,…”
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Docking Studies and α-Substitution Effects on the Anti-Inflammatory Activity of β-Hydroxy-β-arylpropanoic Acids
Published in Molecules (Basel, Switzerland) (05-08-2011)“…Six β-hydroxy-β-aryl propanoic acids were synthesised using a modification of Reformatsky reaction which has already been reported. These acids belong to the…”
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Investigation of solvolysis kinetics of new synthesized fluocinolone acetonide C-21 esters--an in vitro model for prodrug activation
Published in Molecules (Basel, Switzerland) (23-03-2011)“…In this study the solvolysis of newly synthesized fluocinolone acetonide C-21 esters was analysed in comparison with fluocinonide during a 24-hour period of…”
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Evaluation of ACE inhibitors lipophilicity using in silico and chromatographically obtained hydrophobicity parameters
Published in Hemijska industrija (01-01-2013)“…The aim of this study was to compare different calculation methods to determine lipophilicity, expressed as logP value, of seven ACE inhibitors (enalapril,…”
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Phenylpropiophenone derivatives as potential anticancer agents: Synthesis, biological evaluation and quantitative structure–activity relationship study
Published in European journal of medicinal chemistry (01-05-2013)“…Series of twelve chalcone and propafenone derivatives has been synthesized and evaluated for anticancer activities against HeLa, Fem-X, PC-3, MCF-7, LS174 and…”
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Correlation between ultra-high performance liquid chromatography–tandem mass spectrometry and reversed-phase thin-layer chromatography hydrophobicity data for evaluation of angiotensin-converting enzyme inhibitors absorption
Published in Journal of Chromatography A (05-10-2012)“…► The correlation between chromatographic hydrophobicity data and ACE inhibitors absorption. ► The comparison of correlations between RP-TLC and UHPLC–MS…”
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A modified RP-HPLC method for the determination of the pKa values of synthesized β-hydroxy-β-arylalkanoic acids
Published in Journal of the Serbian Chemical Society (2018)“…The pKa values of twelve ?-hydroxy-?-arylalkanoic acids and ibuprofen were determined using a modified RP-HPLC method. The stationary phase was octadecyl…”
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Docking studies and anti-inflammatory activity of beta-hydroxy-beta-arylpropanoic acids
Published in Molecules (Basel, Switzerland) (18-03-2008)“…The article describes a two-step synthesis of diastereomeric 3-hydroxy-2-methyl-3-(4-biphenylyl)butanoic acids. In the first step an intermediate alpha-bromo…”
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HPLC EVALUATION OF SOLVOLYSIS OF A NOVEL ESTER FLUOCINOLONE ACETONIDE 21-(2′-PHENOXYPROPIONATE) IN COMPARISON WITH FLUOCINONIDE
Published in Journal of liquid chromatography & related technologies (01-01-2011)“…In this study the solvolysis of novel fluocinolone acetonide 21-(2′-phenoxypropionate) in comparison with fluocinonide was analyzed in order to evaluate this…”
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Docking Studies and Anti-inflammatory Activity of β-Hydroxy-β-arylpropanoic Acids
Published in Molecules (Basel, Switzerland) (01-03-2008)“…The article describes a two-step synthesis of diastereomeric 3-hydroxy-2-methyl-3-(4-biphenylyl)butanoic acids. In the first step an intermediate α-bromo…”
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Docking Studies and [alpha]-Substitution Effects on the Anti-Inflammatory Activity of [beta]-Hydroxy-[beta]-arylpropanoic Acids
Published in Molecules (Basel, Switzerland) (01-08-2011)“…Six β-hydroxy-β-aryl propanoic acids were synthesised using a modification of Reformatsky reaction which has already been reported. These acids belong to the…”
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Acid-base equilibria of 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid and its labeling with technetium-99m
Published in Journal of the Serbian Chemical Society (01-01-2006)“…The acid-base equilibria of a novel hepatobiliary imaging agent, 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid (DIIODIDA) were studied. The…”
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Docking Studies and Anti-inflammatory Activity of [beta]-Hydroxy-[beta]-arylpropanoic Acids
Published in Molecules (Basel, Switzerland) (01-03-2008)“…The article describes a two-step synthesis of diastereomeric 3-hydroxy-2-methyl-3-(4-biphenylyl)butanoic acids. In the first step an intermediate α-bromo…”
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RP-HPLC determination of vitamins, folic acid and B12 in multivitamin tablets
Published in Journal of the Serbian Chemical Society (01-01-2005)“…A simple and sensitive reversed-phase, ion-pair HPLC method was developed and validated for the simultaneous determination of B-group vitamins, thiamine…”
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