Search Results - "Soslow, R A"

Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma by Garg, K, Soslow, R A

“…Women with hereditary non-polyposis colorectal cancer (HNPCC)/Lynch syndrome have a high risk for endometrial cancer (EC) and frequently present with a…”
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The performance of BRCA1 immunohistochemistry for detecting germline, somatic, and epigenetic BRCA1 loss in high-grade serous ovarian cancer by Meisel, J.L., Hyman, D.M., Garg, K., Zhou, Q., Dao, F., Bisogna, M., Gao, J., Schultz, N.D., Grisham, R.N., Phillips, M., Iasonos, A., Kauff, N.D., Levine, D.A., Soslow, R.A., Spriggs, D.R.

“…BRCA1 expression can be lost by a variety of mechanisms including germline or somatic mutation and promotor hypermethylation. Given the potential importance of…”
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A nomogram for predicting overall survival of women with endometrial cancer following primary therapy: Toward improving individualized cancer care by Abu-Rustum, N.R, Zhou, Q, Gomez, J.D, Alektiar, K.M, Hensley, M.L, Soslow, R.A, Levine, D.A, Chi, D.S, Barakat, R.R, Iasonos, A

“…Abstract Objectives Traditionally we have relied mainly on final FIGO stage to estimate overall oncologic outcome in endometrial cancer patients. However, it…”
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High frequency of β-catenin mutations in borderline endometrioid tumours of the ovary by Oliva, E, Sarrió, D, Brachtel, EF, Sánchez-Estévez, C, Soslow, RA, Moreno-Bueno, G, Palacios, J

“…Some low‐grade endometrioid carcinomas arise from a background of endometrioid tumours of borderline malignancy. To determine the molecular mechanisms involved…”
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Tumor promoting properties of the ETS protein MEF in ovarian cancer by YAO, J. J, LIU, Y, LACORAZZA, H. D, SOSLOW, R. A, SCANDURA, J. M, NIMER, S. D, HEDVAT, C. V

“…We have previously shown that MEF (myeloid ELF1-like factor, also known as ELF4) functions as a transcriptional activator of the interleukin (IL)-8, perforin,…”
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Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer by TUCKER, O. N, DANNENBERG, A. J, FAHEY, T. J, YANG, E. K, FAN ZHANG, LISONG TENG, DALY, J. M, SOSLOW, R. A, MASFERRER, J. L, WOERNER, B. M, KOKI, A. T

“…A large body of evidence suggests that cyclooxygenase-2 (COX-2) is important in gastrointestinal cancer. The purpose of this study was to determine whether…”
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Adjuvant chemotherapy in patients with stage I endometrioid or clear cell ovarian cancer in the platinum era: a Surveillance, Epidemiology, and End Results Cohort Study, 2000–2013 by Oseledchyk, A., Leitao, M.M., Konner, J., O’Cearbhaill, R.E., Zamarin, D., Sonoda, Y., Gardner, G.J., Long Roche, K., Aghajanian, C.A., Grisham, R.N., Brown, C.L., Snyder, A., Chi, D.S., Soslow, R.A., Abu-Rustum, N.R., Zivanovic, O.

“…We sought to evaluate the impact of adjuvant chemotherapy on overall survival (OS) in patients with stage I endometrioid epithelial ovarian cancer (EEOC) or…”
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Endometrial intraepithelial carcinoma with associated peritoneal carcinomatosis by SOSLOW, R. A, PIROG, E, ISACSON, C

“…Endometrial intraepithelial carcinoma (EIC) is a recently described entity, defined as a noninvasive, cytologically malignant lesion that replaces the…”
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Stromal invasion pattern identifies patients at lowest risk of lymph node metastasis in HPV-associated endocervical adenocarcinomas, but is irrelevant in adenocarcinomas unassociated with HPV by Stolnicu, S., Barsan, I., Hoang, L., Patel, P., Terinte, C., Pesci, A., Aviel-Ronen, S., Kiyokawa, T., Alvarado-Cabrero, I., Oliva, E., Park, K.J., Abu-Rustum, N.R., Pike, M.C., Soslow, R.A.

“…The Silva invasion pattern-based classification system stratifies endocervical adenocarcinomas (ECAs) into 3 categories corresponding to risk of metastasis and…”
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Assessment of DNA Ploidy in the ProMisE molecular subgroups of endometrial cancer by Proctor, L, Pradhan, M, Leung, S, Cheng, A, Lee, C.H, Soslow, R.A, Gilks, C.B, Talhouk, A, McAlpine, J.M, Danielsen, H.E, Hoang, L.N

“…Highlights • Abnormal DNA ploidy was significantly higher in the p53 abn molecular group of EC, compared to the other molecular groups. • Abnormal DNA ploidy…”
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Impact of incorporating an algorithm that utilizes sentinel lymph node mapping during minimally invasive procedures on the detection of stage IIIC endometrial cancer by Leitao, M.M, Khoury-Collado, F, Gardner, G, Sonoda, Y, Brown, C.L, Alektiar, K.M, Hensley, M.L, Soslow, R.A, Barakat, R.R, Abu-Rustum, N.R

“…Abstract Objective To determine whether the frequency of cases diagnosed with stage IIIC endometrial cancer is affected by the incorporation of a modified…”
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B‐lineage lymphoblastic lymphoma is a clinicopathologic entity distinct from other histologically similar aggressive lymphomas with blastic morphology by Soslow, Robert A., Baergen, Rebecca N., Warnke, Roger A.

“…BACKGROUND The authors present clinical, histopathologic, and immunophenotypic data regarding B‐lineage lymphoblastic lymphoma (B‐LBL), a rare entity that has…”
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Accuracy of frozen section diagnosis of ovarian borderline tumor by Shih, K.K, Garg, K, Soslow, R.A, Chi, D.S, Abu-Rustum, N.R, Barakat, R.R

“…Abstract Objective The objective of this study was to determine the incidence of invasive cancer in ovarian masses diagnosed as borderline tumor (BT) at the…”
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Distinctive p53 and mdm2 immunohistochemical expression profiles suggest different pathogenetic pathways in poorly differentiated endometrial carcinoma by Soslow, R A, Shen, P U, Chung, M H, Isacson, C

“…Endometrial serous carcinoma (ESC) and FIGO (International Federation of Gynecology and Obstetrics) grade 3 endometrioid adenocarcinoma (EC) are high-grade…”
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Acidic fibroblast growth factor is progressively increased in the development of oesophageal glandular dysplasia and adenocarcinoma by Soslow, R A, Nabeya, Y, Ying, L, Blundell, M, Altorki, N K

“…Aims To determine by immunohistochemistry and amplification of cDNA the relationship between fibroblast growth factor (FGF) expression and progressive changes…”
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Characterization of cyclooxygenase-2 (COX-2) during tumorigenesis in human epithelial cancers: evidence for potential clinical utility of COX-2 inhibitors in epithelial cancers by Koki, A.T., Khan, N.K., Woerner, B.M., Seibert, K., Harmon, J.L., Dannenberg, A.J., Soslow, R.A., Masferrer, J.L.

“…Increased prostaglandins (PGs) are associated with many inflammatory pathophysiological conditions; and are synthesized from arachidonic acid by either of 2…”
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COX‐2 is expressed in human pulmonary, colonic, and mammary tumors by Soslow, Robert A., Dannenberg, Andrew J., Rush, Demaretta, Woerner, B. M., Khan, K. Nasir, Masferrer, J., Koki, Alane T.

“…BACKGROUND The cyclooxygenase (COX) enzyme catalyzes the formation of prostaglandins, which can affect cell proliferation and alter the response of the immune…”
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MIC2, TdT, bcl-2, and CD34 expression in paraffin-embedded high-grade lymphoma/acute lymphoblastic leukemia distinguishes between distinct clinicopathologic entities by Soslow, Robert A, Bhargava, Vivek, Warnke, Roger A

“…We propose that 12E7 (CD99) expression, along with TdT, bcl2, and CD34 reactivity in lymphoblastic lymphoma (LyL)/acute lymphoblastic leukemia (ALL),…”
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Transitional cell neoplasms of the ovary and urinary bladder: a comparative immunohistochemical analysis by Soslow, R A, Rouse, R V, Hendrickson, M R, Silva, E G, Longacre, T A

“…Walthard cell nests, the Brenner tumor (benign, proliferating, low malignant potential, and malignant), and primary ovarian transitional cell carcinoma are…”
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Induction of ovarian cancer by defined multiple genetic changes in a mouse model system by Orsulic, Sandra, Li, Yi, Soslow, Robert A., Vitale-Cross, Lynn A., Gutkind, J.Silvio, Varmus, Harold E.

“…We have developed a mouse model for ovarian carcinoma by using an avian retroviral gene delivery technique for the introduction of multiple genes into somatic…”
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