Search Results - "Sosa Estani, Sergio"

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy by Morillo, Carlos A, Marin-Neto, Jose Antonio, Avezum, Alvaro, Sosa-Estani, Sergio, Rassi, Anis, Rosas, Fernando, Villena, Erick, Quiroz, Roberto, Bonilla, Rina, Britto, Constança, Guhl, Felipe, Velazquez, Elsa, Bonilla, Laura, Meeks, Brandi, Rao-Melacini, Purnima, Pogue, Janice, Mattos, Antonio, Lazdins, Janis, Rassi, Anis, Connolly, Stuart J, Yusuf, Salim

“…In this double-blind, placebo-controlled trial involving 2854 patients with Chagas' cardiomyopathy, no clinical benefit was found with 2 to 3 months of…”
Get full text

Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases by Alvar, Jorge, Alves, Fabiana, Bucheton, Bruno, Burrows, Louise, Büscher, Philippe, Carrillo, Eugenia, Felger, Ingrid, Hübner, Marc P., Moreno, Javier, Pinazo, Maria-Jesus, Ribeiro, Isabela, Sosa-Estani, Sergio, Specht, Sabine, Tarral, Antoine, Wourgaft, Nathalie Strub, Bilbe, Graeme

“…Progress has been made in the control or elimination of tropical diseases, with a significant reduction of incidence. However, there is a risk of re-emergence…”
Get full text

Direct evidence gap on fixed versus adjusted‐dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: Systematic review and individual patient data meta‐analysis by Ciapponi, Agustín, Barreira, Fabiana, Perelli, Lucas, Bardach, Ariel, Gascón, Joaquim, Molina, Israel, Morillo, Carlos, Prado, Nilda, Riarte, Adelina, Torrico, Faustino, Villar, Juan Carlos, Reidel, Sara, Gibbons, Luz, Sosa‐Estani, Sergio

“…Objectives To determine the comparative efficacy and safety of a fixed dose of benznidazole (BZN) with an adjusted‐dose for Trypanosoma cruzi‐seropositive…”
Get full text

International study to evaluate PCR methods for detection of Trypanosoma cruzi DNA in blood samples from Chagas disease patients by Schijman, Alejandro G, Bisio, Margarita, Orellana, Liliana, Sued, Mariela, Duffy, Tomás, Mejia Jaramillo, Ana M, Cura, Carolina, Auter, Frederic, Veron, Vincent, Qvarnstrom, Yvonne, Deborggraeve, Stijn, Hijar, Gisely, Zulantay, Inés, Lucero, Raúl Horacio, Velazquez, Elsa, Tellez, Tatiana, Sanchez Leon, Zunilda, Galvão, Lucia, Nolder, Debbie, Monje Rumi, María, Levi, José E, Ramirez, Juan D, Zorrilla, Pilar, Flores, María, Jercic, Maria I, Crisante, Gladys, Añez, Néstor, De Castro, Ana M, Gonzalez, Clara I, Acosta Viana, Karla, Yachelini, Pedro, Torrico, Faustino, Robello, Carlos, Diosque, Patricio, Triana Chavez, Omar, Aznar, Christine, Russomando, Graciela, Büscher, Philippe, Assal, Azzedine, Guhl, Felipe, Sosa Estani, Sergio, DaSilva, Alexandre, Britto, Constança, Luquetti, Alejandro, Ladzins, Janis

“…A century after its discovery, Chagas disease still represents a major neglected tropical threat. Accurate diagnostics tools as well as surrogate markers of…”
Get full text

Trypanosoma cruzi loop-mediated isothermal amplification (Trypanosoma cruzi Loopamp) kit for detection of congenital, acute and Chagas disease reactivation by Besuschio, Susana A, Picado, Albert, Muñoz-Calderón, Arturo, Wehrendt, Diana P, Fernández, Marisa, Benatar, Alejandro, Diaz-Bello, Zoraida, Irurtia, Cecilia, Cruz, Israel, Ndung'u, Joseph M, Cafferata, María L, Montenegro, Graciela, Sosa Estani, Sergio, Lucero, Raúl H, Alarcón de Noya, Belkisyole, Longhi, Silvia A, Schijman, Alejandro G

“…A Trypanosoma cruzi Loopamp kit was recently developed as a ready-to-use diagnostic method requiring minimal laboratory facilities. We evaluated its diagnostic…”
Get full text

Congenital Chagas disease: an update by Carlier, Yves, Sosa-Estani, Sergio, Luquetti, Alejandro O, Buekens, Pierre

“…Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in 5% of children born from chronically infected mothers in endemic…”
Get full text

Trypanocide treatment of women infected with Trypanosoma cruzi and its effect on preventing congenital Chagas by Fabbro, Diana L, Danesi, Emmaria, Olivera, Veronica, Codebó, Maria Olenka, Denner, Susana, Heredia, Cecilia, Streiger, Mirtha, Sosa-Estani, Sergio

“…With the control of the vectorial and transfusional routes of infection with Trypanosoma cruzi, congenital transmission has become an important source of new…”
Get full text

Integrated control of Chagas disease for its elimination as public health problem - A Review by Sosa-Estani, Sergio, Segura, Elsa Leonor

“…Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to…”
Get full text

Congenital Chagas disease: recommendations for diagnosis, treatment and control of newborns, siblings and pregnant women by Carlier, Yves, Torrico, Faustino, Sosa-Estani, Sergio, Russomando, Graciela, Luquetti, Alejandro, Freilij, Hector, Albajar Vinas, Pedro

Get full text

WHF IASC Roadmap on Chagas Disease by Echeverría, Luis Eduardo, Marcus, Rachel, Novick, Gabriel, Sosa-Estani, Sergio, Ralston, Kate, Zaidel, Ezequiel Jose, Forsyth, Colin, RIbeiro, Antonio Luiz P, Mendoza, Iván, Falconi, Mariano Luis, Mitelman, Jorge, Morillo, Carlos A, Pereiro, Ana Cristina, Pinazo, María Jesús, Salvatella, Roberto, Martinez, Felipe, Perel, Pablo, Liprandi, Álvaro Sosa, Piñeiro, Daniel José, Molina, Gustavo Restrepo

“…Chagas Disease is a neglected tropical disease caused by the protozoan , with some of the most serious manifestations affecting the cardiovascular system. It…”
Get full text

Human Trypanosoma cruzi chronic infection leads to individual level steady-state parasitemia: Implications for drug-trial optimization in Chagas disease by De Salazar, Pablo M, Sosa-Estani, Sergio, Salvador, Fernando, Sulleiro, Elena, Sánchez-Montalvá, Adrián, Ribeiro, Isabela, Molina, Israel, Buckee, Caroline O

“…Currently available drugs against Trypanosoma cruzi infection, which causes 12000 deaths annually, have limitations in their efficacy, safety and tolerability…”
Get full text

The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform by Maguire, Brittany J, Dahal, Prabin, Rashan, Sumayyah, Ngu, Roland, Boon, Anca, Forsyth, Colin, Strub-Wourgraft, Nathalie, Chatelain, Eric, Barreira, Fabiana, Sosa-Estani, Sergio, Guérin, Philippe J

“…Background Chagas disease (CD), caused by the parasite Trypanosoma cruzi , affects ~6–7 million people worldwide. Significant limitations still exist in our…”
Get full text

Course of Chronic Trypanosoma cruzi Infection after Treatment Based on Parasitological and Serological Tests: A Systematic Review of Follow-Up Studies by Sguassero, Yanina, Cuesta, Cristina B, Roberts, Karen N, Hicks, Elizabeth, Comandé, Daniel, Ciapponi, Agustín, Sosa-Estani, Sergio

“…Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi (T. cruzi). It is endemic in Latin American countries outside the Caribbean. The current…”
Get full text

Fixed vs adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: A systematic review and meta-analysis by Ciapponi, Agustín, Barreira, Fabiana, Perelli, Lucas, Bardach, Ariel, Gascón, Joaquim, Molina, Israel, Morillo, Carlos, Prado, Nilda, Riarte, Adelina, Torrico, Faustino, Ribeiro, Isabela, Villar, Juan Carlos, Sosa-Estani, Sergio

“…Chagas disease is a neglected disease that remains a public health threat, particularly in Latin America. The most important treatment options are…”
Get full text

A new patient registry for Chagas disease by Hotez, Peter, Bottazzi, Maria Elena, Strub-Wourgaft, Nathalie, Sosa-Estani, Sergio, Torrico, Faustino, Pajín, Leire, Abril, Marcelo, Sancho, Javier

Get full text

COVID-19 : implications for people with Chagas disease by Zaidel, Ezequiel José, Forsyth, Colin J., Novick, Gabriel, Marcus, Rachel, Ribeiro, Antonio Luiz P., Pinazo, Maria-Jesus, Morillo, Carlos A., Echeverría, Luis Eduardo, Shikanai-Yasuda, Maria Aparecida, Buekens, Pierre, Perel, Pablo, Meymandi, Sheba K., Ralston, Kate, Pinto, Fausto J., Sosa-Estani, Sergio

“…© 2020 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0),…”
Get full text

A standardized clinical database for research in Chagas disease: The NHEPACHA network by González Martínez, Adriana, Losada-Galván, Irene, Gabaldón-Figueira, Juan Carlos, Martínez-Peinado, Nieves, Saraiva, Roberto Magalhães, Fernández, Marisa Liliana, Ramsey, Janine M, Noya-González, Oscar, Alarcón de Noya, Belkisyole, Schijman, Alejandro Gabriel, Berón, Soledad, Abril, Marcelo, Gascón, Joaquim, Sosa-Estani, Sergio, Pinazo, María Jesús, Alonso-Padilla, Julio, Hasslocher-Moreno, Alejandro Marcel

“…The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research…”
Get full text

Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: The BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT) by Marin-Neto, Jose Antonio, MD, Rassi, Anis, MD, Morillo, Carlos A., MD, Avezum, Alvaro, MD, Connolly, Stuart J., MD, Sosa-Estani, Sergio, MD, Rosas, Fernando, MD, Yusuf, Salim, MD

“…Background Benznidazole is effective for treating acute and chronic (recently acquired) Trypanosoma cruzi infection (Chagas' disease). Recent data indicate…”
Get full text

Target Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment by Porrás, Analía I, Yadon, Zaida E, Altcheh, Jaime, Britto, Constança, Chaves, Gabriela C, Flevaud, Laurence, Martins-Filho, Olindo Assis, Ribeiro, Isabela, Schijman, Alejandro G, Shikanai-Yasuda, Maria Aparecida, Sosa-Estani, Sergio, Stobbaerts, Eric, Zicker, Fabio

“…  The complexity of the equipment that is required, the need for highly trained personnel, and the need for the patient to come to the health center more than…”
Get full text

Higher congenital transmission rate of Trypanosoma cruzi associated with family history of congenital transmission by Danesi, Emmaría, Fabbro, Diana Lucrecia, Segura, Elsa Leonor, Sosa-Estani, Sergio

“…Congenital transmission (CT) of Trypanosoma cruzi has led to globalization of Chagas disease and its growing relevance as a public health problem. Although the…”
Get full text