Search Results - "Sorvillo, Luca"

Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells by Sapio, Luigi, Sorvillo, Luca, Illiano, Michela, Chiosi, Emilio, Spina, Annamaria, Naviglio, Silvio

“…Due to its expression profile, triple-negative breast cancer (TNBC) is refractory to the most effective targeted therapies available for breast cancer…”
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Inorganic phosphate as a signaling molecule: a potential strategy in osteosarcoma treatment by Spina, Annamaria, Sorvillo, Luca, Esposito, Antonietta, Borgia, Alessia, Sapio, Luigi, Naviglio, Silvio

“…Inorganic phosphate (Pi) is an essential nutrient to living organisms. It plays a key role in diverse biological processes, including osteoblast…”
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Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells by SPINA, ANNAMARIA, SORVILLO, LUCA, CHIOSI, EMILIO, ESPOSITO, ANTONIETTA, DI MAIOLO, FRANCESCA, SAPIO, LUIGI, CARAGLIA, MICHELE, NAVIGLIO, SILVIO

“…Novel therapeutic approaches are required for the treatment of osteosarcoma. Combination chemotherapy is receiving increased attention in order to identify…”
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Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells by Naviglio, Silvio, Di Gesto, Davide, Sorrentino, Annunziata, Illiano, Fausto, Sorvillo, Luca, Abbruzzese, Alberto, Marra, Monica, Caraglia, Michele, Chiosi, Emilio, Spina, Annamaria, Illiano, Gennaro

“…Elevation of cAMP inhibits the proliferation and expression of transformed phenotype in several cell types, including breast cancer cells. Leptin has been…”
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Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway by Spina, Annamaria, Sorvillo, Luca, Di Maiolo, Francesca, Esposito, Antonietta, D'Auria, Raffaella, Di Gesto, Davide, Chiosi, Emilio, Naviglio, Silvio

“…Osteosarcoma is the most common malignant primary bone tumor in children and adolescents. The clinical outcome for osteosarcoma remains discouraging despite…”
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Protein kinase A as a biological target in cancer therapy by Naviglio, Silvio, Caraglia, Michele, Abbruzzese, Alberto, Chiosi, Emilio, Di Gesto, Davide, Marra, Monica, Romano, Maria, Sorrentino, Annunziata, Sorvillo, Luca, Spina, Annamaria, Illiano, Gennaro

“…cAMP is a second messenger that plays a role in intracellular signal transduction of various stimuli. a major function of cAMP in eukaryotes is activation of…”
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cAMP Elevation Down-Regulates β3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells by Spina, Annamaria, Di Maiolo, Francesca, Esposito, Antonietta, Sapio, Luigi, Chiosi, Emilio, Sorvillo, Luca, Naviglio, Silvio

“…Breast cancer is one of the most common malignancies and a major cause of cancer death among women worldwide. The high mortality rate associated with breast…”
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Inorganic Phosphate as a Novel Signaling Molecule with Antiproliferative Action in MDA-MB-231 Breast Cancer Cells by Spina, Annamaria, Sapio, Luigi, Esposito, Antonietta, Di Maiolo, Francesca, Sorvillo, Luca, Naviglio, Silvio

“…Inorganic phosphate (Pi) is an essential nutrient for living organisms. It plays a key role in diverse physiological functions, including osteoblast…”
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cAMP Elevation Down-Regulates β 3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells by Spina, Annamaria, Di Maiolo, Francesca, Esposito, Antonietta, Sapio, Luigi, Chiosi, Emilio, Sorvillo, Luca, Naviglio, Silvio

“…Breast cancer is one of the most common malignancies and a major cause of cancer death among women worldwide. The high mortality rate associated with breast…”
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Inorganic phosphate inhibits growth of human osteosarcoma U2OS cells via adenylate cyclase/cAMP pathway by Naviglio, Silvio, Spina, Annamaria, Chiosi, Emilio, Fusco, Anna, Illiano, Fausto, Pagano, Mario, Romano, Maria, Senatore, Giovanna, Sorrentino, Annunziata, Sorvillo, Luca, Illiano, Gennaro

“…In order to elucidate how phosphate regulates cellular functions, we investigated the effects of inorganic phosphate (Pi) on adenylate cyclase (AC)/cyclic AMP…”
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Change in TNF-alpha receptor expression is a relevant event in doxorubicin-induced H9c2 cardiomyocyte cell death by Chiosi, Emilio, Spina, Annamaria, Sorrentino, Annunziata, Romano, Maria, Sorvillo, Luca, Senatore, Giovanna, D'Auria, Raffaella, Abbruzzese, Alberto, Caraglia, Michele, Naviglio, Silvio, Illiano, Gennaro

“…Doxorubicin (Doxo) is a widely used anticancer drug given for the treatment of leukemias, lymphomas, and solid tumors. Despite its potent antitumor effects,…”
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cAMP Elevation Down-Regulates [beta]3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells by Spina, Annamaria, Di Maiolo, Francesca, Esposito, Antonietta, Sapio, Luigi, Chiosi, Emilio, Sorvillo, Luca, Naviglio, Silvio

“…Breast cancer is one of the most common malignancies and a major cause of cancer death among women worldwide. The high mortality rate associated with breast…”
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Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells by Spina, Annamaria, Di Maiolo, Francesca, Esposito, Antonietta, D'Auria, Raffaella, Di Gesto, Davide, Chiosi, Emilio, Sorvillo, Luca, Naviglio, Silvio

“…Breast cancer is a major cause of cancer death in women in the world. Triple-negative breast cancers, which accounts for 10-20% of all mammary tumours, are…”
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