Search Results - "Sorum, Ben"

Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs by Kern, David M., Sorum, Ben, Mali, Sonali S., Hoel, Christopher M., Sridharan, Savitha, Remis, Jonathan P., Toso, Daniel B., Kotecha, Abhay, Bautista, Diana M., Brohawn, Stephen G.

“…SARS-CoV-2 ORF3a is a putative viral ion channel implicated in autophagy inhibition, inflammasome activation and apoptosis. 3a protein and anti-3a antibodies…”
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Timing of CFTR Pore Opening and Structure of Its Transition State by Sorum, Ben, Czégé, Dávid, Csanády, László

“…In CFTR, the chloride ion channel mutated in cystic fibrosis (CF) patients, pore opening is coupled to ATP-binding-induced dimerization of two cytosolic…”
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Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2 by Sorum, Ben, Docter, Trevor, Panico, Vincent, Rietmeijer, Robert A., Brohawn, Stephen G.

“…TRAAK, TREK-1, and TREK-2 are mechanosensitive two-pore domain K+ (K2P) channels that contribute to action potential propagation, sensory transduction, and…”
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Asymmetry of movements in CFTR's two ATP sites during pore opening serves their distinct functions by Sorum, Ben, Töröcsik, Beáta, Csanády, László

“…CFTR, the chloride channel mutated in cystic fibrosis (CF) patients, is opened by ATP binding to two cytosolic nucleotide binding domains (NBDs), but…”
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Ultrasound activates mechanosensitive TRAAK K⁺ channels through the lipid membrane by Sorum, Ben, Rietmeijer, Robert A., Gopakumar, Karthika, Adesnik, Hillel, Brohawn, Stephen G.

“…Ultrasound modulates the electrical activity of excitable cells and offers advantages over other neuromodulatory techniques; for example, it can be…”
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Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK by Rietmeijer, Robert A., Sorum, Ben, Li, Baobin, Brohawn, Stephen G.

“…TRAAK is a mechanosensitive two-pore domain K+ (K2P) channel localized to nodes of Ranvier in myelinated neurons. TRAAK deletion in mice results in mechanical…”
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Quantifying pressure and ultrasound activation of the mechanosensitive K+ channel TRAAK by Docter, Trevor, Sorum, Ben, Rietmeijer, Robert A., Brohawn, Steve

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Author Correction: Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs by Kern, David M., Sorum, Ben, Mali, Sonali S., Hoel, Christopher M., Sridharan, Savitha, Remis, Jonathan P., Toso, Daniel B., Kotecha, Abhay, Bautista, Diana M., Brohawn, Stephen G.

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