Search Results - "Soruco, Marcela M."

new player in X identification: the CLAMP protein is a key factor in Drosophila dosage compensation by Soruco, Marcela M. L, Larschan, Erica

“…Dosage compensation adjusts the expression levels of genes on one or both targeted sex chromosomes in heterogametic species. This process results in the…”
Get full text

In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements by Groff, Abigail F., Sanchez-Gomez, Diana B., Soruco, Marcela M.L., Gerhardinger, Chiara, Barutcu, A. Rasim, Li, Eric, Elcavage, Lara, Plana, Olivia, Sanchez, Lluvia V., Lee, James C., Sauvageau, Martin, Rinn, John L.

“…The Linc-p21 locus, encoding a long non-coding RNA, plays an important role in p53 signaling, cell-cycle regulation, and tumor suppression. However, despite…”
Get full text

Identification of chromatin-associated regulators of MSL complex targeting in Drosophila dosage compensation by Larschan, Erica, Soruco, Marcela M L, Lee, Ok-Kyung, Peng, Shouyong, Bishop, Eric, Chery, Jessica, Goebel, Karen, Feng, Jessica, Park, Peter J, Kuroda, Mitzi I

“…Sex chromosome dosage compensation in Drosophila provides a model for understanding how chromatin organization can modulate coordinate gene regulation. Male…”
Get full text

The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation by Soruco, Marcela M L, Chery, Jessica, Bishop, Eric P, Siggers, Trevor, Tolstorukov, Michael Y, Leydon, Alexander R, Sugden, Arthur U, Goebel, Karen, Feng, Jessica, Xia, Peng, Vedenko, Anastasia, Bulyk, Martha L, Park, Peter J, Larschan, Erica

“…The Drosophila male-specific lethal (MSL) dosage compensation complex increases transcript levels on the single male X chromosome to equal the transcript…”
Get full text

The essential Drosophila CLAMP protein differentially regulates non-coding roX RNAs in male and females by Urban, Jennifer A., Doherty, Caroline A., Jordan, William T., Bliss, Jacob E., Feng, Jessica, Soruco, Marcela M., Rieder, Leila E., Tsiarli, Maria A., Larschan, Erica N.

“…Heterogametic species require chromosome-wide gene regulation to compensate for differences in sex chromosome gene dosage. In Drosophila melanogaster ,…”
Get full text