Search Results - "Sorokina, Maria"
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Review on natural products databases: where to find data in 2020
Published in Journal of cheminformatics (03-04-2020)“…Natural products (NPs) have been the centre of attention of the scientific community in the last decencies and the interest around them continues to grow…”
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COCONUT online: Collection of Open Natural Products database
Published in Journal of cheminformatics (10-01-2021)“…Natural products (NPs) are small molecules produced by living organisms with potential applications in pharmacology and other industries as many of them are…”
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NaPLeS: a natural products likeness scorer—web application and database
Published in Journal of cheminformatics (09-08-2019)“…Natural products (NPs), often also referred to as secondary metabolites, are small molecules synthesised by living organisms. Natural products are of interest…”
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E-cadherin is under constitutive actomyosin-generated tension that is increased at cell–cell contacts upon externally applied stretch
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2012)“…Classical cadherins are transmembrane proteins at the core of intercellular adhesion complexes in cohesive metazoan tissues. The extracellular domain of…”
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Hypercoagulation detected by routine and global laboratory hemostasis assays in patients with infective endocarditis
Published in PloS one (15-12-2021)“…Coagulation system is heavily involved into the process of infective endocarditis (IE) vegetation formation and can facilitate further embolization. In this…”
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The LOTUS initiative for open knowledge management in natural products research
Published in eLife (26-05-2022)“…Contemporary bioinformatic and chemoinformatic capabilities hold promise to reshape knowledge management, analysis and interpretation of data in natural…”
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MAW: the reproducible Metabolome Annotation Workflow for untargeted tandem mass spectrometry
Published in Journal of cheminformatics (04-03-2023)“…Mapping the chemical space of compounds to chemical structures remains a challenge in metabolomics. Despite the advancements in untargeted liquid…”
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Enhanced Production of Nitrogenated Metabolites with Anticancer Potential in Aristolochia manshuriensis Hairy Root Cultures
Published in International journal of molecular sciences (08-07-2023)“…is a relic liana, which is widely used in traditional Chinese herbal medicine and is endemic to the Manchurian floristic region. Since this plant is rare and…”
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Effect of Stress Signals and Ib-rolB/C Overexpression on Secondary Metabolite Biosynthesis in Cell Cultures of Ipomoea batatas
Published in International journal of molecular sciences (01-12-2022)“…is a vital root crop and a source of caffeoylquinic acid derivatives (CQAs) with potential health-promoting benefits. As a naturally transgenic plant, contains…”
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MAYGEN: an open-source chemical structure generator for constitutional isomers based on the orderly generation principle
Published in Journal of cheminformatics (03-07-2021)“…The generation of constitutional isomer chemical spaces has been a subject of cheminformatics since the early 1960s, with applications in structure elucidation…”
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Too sweet: cheminformatics for deglycosylation in natural products
Published in Journal of cheminformatics (04-11-2020)“…Sugar units in natural products are pharmacokinetically important but often redundant and therefore obstructing the study of the structure and function of the…”
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Heterogeneity of Integrin αIIbβ3 Function in Pediatric Immune Thrombocytopenia Revealed by Continuous Flow Cytometry Analysis
Published in International journal of molecular sciences (25-04-2020)“…Immune thrombocytopenia (ITP) is an autoimmune condition primarily induced by the loss of immune tolerance to the platelet glycoproteins. Here we develop a…”
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Global ocean resistome revealed: Exploring antibiotic resistance gene abundance and distribution in TARA Oceans samples
Published in Gigascience (01-05-2020)“…Abstract Background The rise of antibiotic resistance (AR) in clinical settings is of great concern. Therefore, the understanding of AR mechanisms, evolution,…”
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Untargeted metabolomics to expand the chemical space of the marine diatom Skeletonema marinoi
Published in Frontiers in microbiology (05-12-2023)“…Diatoms (Bacillariophyceae) are aquatic photosynthetic microalgae with an ecological role as primary producers in the aquatic food web. They account…”
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Description and Analysis of Glycosidic Residues in the Largest Open Natural Products Database
Published in Biomolecules (Basel, Switzerland) (24-03-2021)“…Natural products (NPs), biomolecules produced by living organisms, inspire the pharmaceutical industry and research due to their structural characteristics and…”
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DECIMER-Segmentation: Automated extraction of chemical structure depictions from scientific literature
Published in Journal of cheminformatics (08-03-2021)“…Chemistry looks back at many decades of publications on chemical compounds, their structures and properties, in scientific articles. Liberating this knowledge…”
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A new network representation of the metabolism to detect chemical transformation modules
Published in BMC bioinformatics (14-11-2015)“…Metabolism is generally modeled by directed networks where nodes represent reactions and/or metabolites. In order to explore metabolic pathway conservation and…”
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Biosynthesis of Functional Silver Nanoparticles Using Callus and Hairy Root Cultures of Aristolochia manshuriensis
Published in Journal of functional biomaterials (01-09-2023)“…This study delves into the novel utilization of Aristolochia manshuriensis cultured cells for extracellular silver nanoparticles (AgNPs) synthesis without the…”
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Draft genome assembly and sequencing dataset of the marine diatom Skeletonema cf. costatum RCC75
Published in Data in brief (01-04-2022)“…Diatoms (Bacillariophyceae) are a major constituent of the phytoplankton and have a universally recognized ecological importance. Between 1,000 and 1,300…”
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A Catalog of Natural Products Occurring in Watermelon—Citrullus lanatus
Published in Frontiers in nutrition (Lausanne) (14-09-2021)“…Graphical Abstract Sweet dessert watermelon ( Citrullus lanatus ) is one of the most important vegetable crops consumed throughout the world. The chemical…”
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