Search Results - "Soriano, Silvia F."

CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface by Martínez-Muñoz, Laura, Barroso, Rubén, Dyrhaug, Sunniva Y, Navarro, Gemma, Lucas, Pilar, Soriano, Silvia F, Vega, Beatriz, Costas, Coloma, Muñoz-Fernández, M Ángeles, Santiago, César, Rodríguez Frade, José Miguel, Franco, Rafael, Mellado, Mario

“…CCR5 and CXCR4, the respective cell surface coreceptors of R5 and X4 HIV-1 strains, both form heterodimers with CD4, the principal HIV-1 receptor. Using…”
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A novel high-content analysis tool reveals Rab8-driven cytoskeletal reorganization through Rho GTPases, calpain and MT1-MMP by Bravo-Cordero, José J, Cordani, Marco, Soriano, Silvia F, Díez, Begoña, Muñoz-Agudo, Carmen, Casanova-Acebes, María, Boullosa, César, Guadamillas, Marta C, Ezkurdia, Iakes, González-Pisano, David, Del Pozo, Miguel A, Montoya, María C

“…Rab8 is a small Ras-related GTPase that regulates polarized membrane transport to the plasma membrane. Here, we developed a high-content analysis (HCA) tool to…”
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A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress by Nombela-Arrieta, César, Mempel, Thorsten R, Soriano, Silvia F, Mazo, Irina, Wymann, Matthias P, Hirsch, Emilio, Martínez-A, Carlos, Fukui, Yoshinori, von Andrian, Ulrich H, Stein, Jens V

“…Recent observations using multiphoton intravital microscopy (MP-IVM) have uncovered an unexpectedly high lymphocyte motility within peripheral lymph nodes…”
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Naive B-cell trafficking is shaped by local chemokine availability and LFA-1–independent stromal interactions by Coelho, Fernanda M., Natale, Daniela, Soriano, Silvia F., Hons, Miroslav, Swoger, Jim, Mayer, Jürgen, Danuser, Renzo, Scandella, Elke, Pieczyk, Markus, Zerwes, Hans-Günter, Junt, Tobias, Sailer, Andreas W., Ludewig, Burkhard, Sharpe, James, Figge, Marc Thilo, Stein, Jens V.

“…It is not known how naive B cells compute divergent chemoattractant signals of the T-cell area and B-cell follicles during in vivo migration. Here, we used…”
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Chemokines integrate JAK/STAT and G‐protein pathways during chemotaxis and calcium flux responses by Soriano, Silvia F., Serrano, Antonio, Hernanz‐Falcón, Patricia, de Ana, Ana Martín, Monterrubio, María, Martínez‐A, Carlos, Rodríguez‐Frade, J. Miguel, Mellado, Mario

“…The JAK/STAT (Janus kinase / signaling transducer and activator of transcription) signaling pathway is implicated in converting stationary epithelial cells to…”
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Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor by Rodríguez-Frade, José Miguel, del Real, Gustavo, Serrano, Antonio, Hernanz-Falcón, Patricia, Soriano, Silvia F, Vila-Coro, Antonio J, de Ana, Ana Martín, Lucas, Pilar, Prieto, Ignacio, Martínez-A, Carlos, Mellado, Mario

“…The identification of chemokine receptors as HIV‐1 coreceptors has focused research on developing strategies to prevent HIV‐1 infection. We generated CCR2‐01,…”
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L-selectin-negative CCR7 − effector and memory CD8 + T cells enter reactive lymph nodes and kill dendritic cells by Hons, Miroslav, Sallusto, Federica, Stein, Jens V, Polley, Rosalind, Lanzavecchia, Antonio, Martín-Fontecha, Alfonso, Soriano, Silvia F, Germain, Ronald N, Guarda, Greta, Huang, Alex Y

“…T lymphocytes lacking the lymph node-homing receptors L-selectin and CCR7 do not migrate to lymph nodes in the steady state. Instead, we found here that lymph…”
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In vivo analysis of uropod function during physiological T cell trafficking by Soriano, Silvia F, Hons, Miroslav, Schumann, Kathrin, Kumar, Varsha, Dennier, Timo J, Lyck, Ruth, Sixt, Michael, Stein, Jens V

“…Migrating lymphocytes acquire a polarized phenotype with a leading and a trailing edge, or uropod. Although in vitro experiments in cell lines or activated…”
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Functional inactivation of CXC chemokine receptor 4-mediated responses through SOCS3 up-regulation by Soriano, Silvia F, Hernanz-Falcón, Patricia, Rodríguez-Frade, José Miguel, De Ana, Ana Martín, Garzón, Ruth, Carvalho-Pinto, Carla, Vila-Coro, Antonio J, Zaballos, Angel, Balomenos, Dimitrios, Martínez-A, Carlos, Mellado, Mario

“…Hematopoietic cell growth, differentiation, and chemotactic responses require coordinated action between cytokines and chemokines. Cytokines promote receptor…”
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CXCR4-mediated Suppressor of Cytokine Signaling Up-regulation Inactivates Growth Hormone Function by Garzon, Ruth, Soriano, Silvia F, Rodriguez-Frade, Jose Miguel, Gomez, Lucio, Martin De Ana, Ana, Sanchez-Gomez, Myriam, Martinez-A, Carlos, Mellado, Mario

“…Coordinated action between cytokines and chemokines is required for effective endocrine and immune responses. Proteins of both families promote receptor…”
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Identification of amino acid residues crucial for chemokine receptor dimerization by Valencia, Alfonso, Rodríguez-Frade, José Miguel, Mellado, Mario, Serrano, Antonio, Juan, David, del Sol, Antonio, Soriano, Silvia F, Martínez-A, Carlos, Roncal, Fernando, Gómez, Lucio, Hernanz-Falcón, Patricia

“…Chemokines coordinate leukocyte trafficking by promoting oligomerization and signaling by G protein-coupled receptors; however, it is not known which amino…”
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CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathway by Stein, Jens V., Soriano, Silvia F., M'rini, Christine, Nombela-Arrieta, César, González de Buitrago, Gonzalo, Rodrı́guez-Frade, José Miguel, Mellado, Mario, Girard, Jean-Philippe, Martı́nez-A., Carlos

“…Homing of blood-borne lymphocytes to peripheral lymph nodes (PLNs) is a multistep process dependent on the sequential engagement of L-selectin, which mediates…”
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CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120 IIIB binding to the cell surface by Martínez-Muñoz, Laura, Barroso, Rubén, Dyrhaug, Sunniva Y., Navarro, Gemma, Lucas, Pilar, Soriano, Silvia F., Vega, Beatriz, Costas, Coloma, Muñoz-Fernández, M. Ángeles, Santiago, César, Frade, José Miguel Rodríguez, Franco, Rafael, Mellado, Mario

“…HIV-1 enters host cells via CD4 and the coreceptors CXCR4 or CCR5. Most HIV-1 variants isolated from newly infected individuals use CCR5 (R5 strains) and…”
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CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120^sub IIIB^ binding to the cell surface by Martínez-Muñoz, Laura, Barroso, Rubén, Dyrhaug, Sunniva Y, Navarro, Gemma, Lucas, Pilar, Soriano, Silvia F, Vega, Beatriz, Costas, Coloma, Muñoz-Fernández, M Ángeles, Santiago, César, Frade, José Miguel Rodríguez, Franco, Rafael, Mellado, Mario

“…CCR5 and CXCR4, the respective cell surface coreceptors of R5 and X4 HIV-1 strains, both form heterodimers with CD4, the principal HIV-1 receptor. Using…”
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CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIBbinding to the cell surface by Martínez-Muñoz, Laura, Barroso, Rubén, Dyrhaug, Sunniva Y., Navarro, Gemma, Lucas, Pilar, Soriano, Silvia F., Vega, Beatriz, Costas, Coloma, Munñoz-Fernández, M. Ángeles, Santiago, César, Frade, José Miguel Rodríguez, Franco, Rafael, Mellado, Mario

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CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120 sub( IIIB) binding to the cell surface by Martinez-Munoz, Laura, Barroso, Ruben, Dyrhaug, Sunniva Y, Navarro, Gemma, Lucas, Pilar, Soriano, Silvia F, Vega, Beatriz, Costas, Coloma, Munoz-Fernandez, M Angeles, Santiago, Cesar, Frade, Jose Miguel Rodriguez, Franco, Rafael, Mellado, Mario

“…CCR5 and CXCR4, the respective cell surface coreceptors of R5 and X4 HIV-1 strains, both form heterodimers with CD4, the principal HIV-1 receptor. Using…”
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The Chemokine Stromal Cell-Derived Factor-1α Modulates α4β7 Integrin-Mediated Lymphocyte Adhesion to Mucosal Addressin Cell Adhesion Molecule-1 and Fibronectin by Wright, Natalia, Hidalgo, Andrés, Rodríguez-Frade, José Miguel, Soriano, Silvia F., Mellado, Mario, Parmo-Cabañas, Marisa, Briskin, Michael J., Teixidó, Joaquin

“…The interaction between the integrin α4β7 and its ligand, mucosal addressin cell adhesion molecule-1, on high endothelial venules represents a key adhesion…”
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Comprehensive assessment of quantum dots for multispectral twophoton imaging of dynamic leukocyte migration in lymph nodes by Natale, Daniela, Soriano, Silvia F., Coelho, Fernanda M., Hons, Miroslav, Stein, Jens V.

“…In recent years, intravital twophoton microscopy (2PM) has emerged as the appropriate technique for direct in situ imaging of immune cell dynamics inside…”
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L-selectin-negative CCR7 super(-) effector and memory CD8 super(+) T cells enter reactive lymph nodes and kill dendritic cells by Guarda, Greta, Hons, Miroslav, Soriano, Silvia F, Huang, Alex Y, Polley, Rosalind, Martin-Fontecha, Alfonso, Stein, Jens V, Germain, Ronald N, Lanzavecchia, Antonio, Sallusto, Federica

“…T lymphocytes lacking the lymph node-homing receptors L-selectin and CCR7 do not migrate to lymph nodes in the steady state. Instead, we found here that lymph…”
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The chemokine stromal cell-derived factor-1 alpha modulates alpha 4 beta 7 integrin-mediated lymphocyte adhesion to mucosal addressin cell adhesion molecule-1 and fibronectin by Wright, Natalia, Hidalgo, Andrés, Rodríguez-Frade, José Miguel, Soriano, Silvia F, Mellado, Mario, Parmo-Cabañas, Marisa, Briskin, Michael J, Teixidó, Joaquin

“…The interaction between the integrin alpha(4)beta(7) and its ligand, mucosal addressin cell adhesion molecule-1, on high endothelial venules represents a key…”
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