Search Results - "Soriani, Marco"

Unraveling Neisseria meningitidis pathogenesis: from functional genomics to experimental models by Soriani, Marco

“…is a harmless commensal bacterium finely adapted to humans. Unfortunately, under "privileged" conditions, it adopts a "devious" lifestyle leading to…”
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3D Reconstruction of the Human Airway Mucosa In Vitro as an Experimental Model to Study NTHi Infections by Marrazzo, Pasquale, Maccari, Silvia, Taddei, Annarita, Bevan, Luke, Telford, John, Soriani, Marco, Pezzicoli, Alfredo

“…We have established an in vitro 3D system which recapitulates the human tracheo-bronchial mucosa comprehensive of the pseudostratified epithelium and the…”
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Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure by De Chiara, Matteo, Hood, Derek, Muzzi, Alessandro, Pickard, Derek J., Perkins, Tim, Pizza, Mariagrazia, Dougan, Gordon, Rappuoli, Rino, Moxon, E. Richard, Soriani, Marco, Donati, Claudio

“…One of the main hurdles for the development of an effective and broadly protective vaccine against nonencapsulated isolates of Haemophilus influenzae (NTHi)…”
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Clostridium difficile Toxins Facilitate Bacterial Colonization by Modulating the Fence and Gate Function of Colonic Epithelium by Kasendra, Magdalena, Barrile, Riccardo, Leuzzi, Rosanna, Soriani, Marco

“…The contribution of Clostridium difficile toxin A and (TcdA and TcdB) to cellular intoxication has been studied extensively, but their impact on bacterial…”
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Pathogenic E. coli exploits SslE mucinase activity to translocate through the mucosal barrier and get access to host cells by Valeri, Maria, Rossi Paccani, Silvia, Kasendra, Magdalena, Nesta, Barbara, Serino, Laura, Pizza, Mariagrazia, Soriani, Marco

“…SslE is a zinc-metalloprotease involved in the degradation of mucin substrates and recently proposed as a potential vaccine candidate against pathogenic E…”
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Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk by Baddal, Buket, Muzzi, Alessandro, Censini, Stefano, Calogero, Raffaele A, Torricelli, Giulia, Guidotti, Silvia, Taddei, Anna R, Covacci, Antonello, Pizza, Mariagrazia, Rappuoli, Rino, Soriani, Marco, Pezzicoli, Alfredo

“…The ability to adhere and adapt to the human respiratory tract mucosa plays a pivotal role in the pathogenic lifestyle of nontypeable Haemophilus influenzae…”
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The Human Pathogen Streptococcus pyogenes Releases Lipoproteins as Lipoprotein-rich Membrane Vesicles by Biagini, Massimiliano, Garibaldi, Manuela, Aprea, Susanna, Pezzicoli, Alfredo, Doro, Francesco, Becherelli, Marco, Taddei, Anna Rita, Tani, Chiara, Tavarini, Simona, Mora, Marirosa, Teti, Giuseppe, D'Oro, Ugo, Nuti, Sandra, Soriani, Marco, Margarit, Immaculada, Rappuoli, Rino, Grandi, Guido, Norais, Nathalie

“…Bacterial lipoproteins are attractive vaccine candidates because they represent a major class of cell surface-exposed proteins in many bacteria and are…”
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Identification of novel genomic islands coding for antigenic pilus‐like structures in Streptococcus agalactiae by Rosini, Roberto, Rinaudo, Cira Daniela, Soriani, Marco, Lauer, Peter, Mora, Marirosa, Maione, Domenico, Taddei, Annarita, Santi, Isabella, Ghezzo, Claudia, Brettoni, Cecilia, Buccato, Scilla, Margarit, Immaculada, Grandi, Guido, Telford, John L.

“…Summary We have recently reported the presence of covalently linked pilus‐like structures in the human pathogen, Group B Streptococcus (GBS). The pilus operon…”
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CsrRS Regulates Group B Streptococcus Virulence Gene Expression in Response to Environmental pH: a New Perspective on Vaccine Development by SANTI, Isabella, GRIFANTINI, Renata, JIANG, Sheng-Mei, BRETTONI, Cecilia, GRANDI, Guido, WESSELS, Michael R, SORIANI, Marco

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SslE elicits functional antibodies that impair in vitro mucinase activity and in vivo colonization by both intestinal and extraintestinal Escherichia coli strains by Nesta, Barbara, Valeri, Maria, Spagnuolo, Angela, Rosini, Roberto, Mora, Marirosa, Donato, Paolo, Alteri, Christopher J, Del Vecchio, Mariangela, Buccato, Scilla, Pezzicoli, Alfredo, Bertoldi, Isabella, Buzzigoli, Lapo, Tuscano, Giovanna, Falduto, Maria, Rippa, Valentina, Ashhab, Yaqoub, Bensi, Giuliano, Fontana, Maria Rita, Seib, Kate L, Mobley, Harry L T, Pizza, Mariagrazia, Soriani, Marco, Serino, Laura

“…SslE, the Secreted and surface-associated lipoprotein from Escherichia coli, has recently been associated to the M60-like extracellular zinc-metalloprotease…”
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The Fimbrial Protein FlfA from Gallibacterium anatis Is a Virulence Factor and Vaccine Candidate by Bager, Ragnhild J, Nesta, Barbara, Pors, Susanne E, Soriani, Marco, Serino, Laura, Boyce, John D, Adler, Ben, Bojesen, Anders M

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FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections by Nesta, Barbara, Spraggon, Glen, Alteri, Christopher, Moriel, Danilo Gomes, Rosini, Roberto, Veggi, Daniele, Smith, Sara, Bertoldi, Isabella, Pastorello, Ilaria, Ferlenghi, Ilaria, Fontana, Maria Rita, Frankel, Gad, Mobley, Harry L T, Rappuoli, Rino, Pizza, Mariagrazia, Serino, Laura, Soriani, Marco

“…The increasing antibiotic resistance of pathogenic Escherichia coli species and the absence of a pan-protective vaccine pose major health concerns. We recently…”
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LytM proteins play a crucial role in cell separation, outer membrane composition, and pathogenesis in nontypeable Haemophilus influenzae by Ercoli, Giuseppe, Tani, Chiara, Pezzicoli, Alfredo, Vacca, Irene, Martinelli, Manuele, Pecetta, Simone, Petracca, Roberto, Rappuoli, Rino, Pizza, Mariagrazia, Norais, Nathalie, Soriani, Marco, Aricò, Beatrice

“…LytM proteins belong to a family of bacterial metalloproteases. In Gram-negative bacteria, LytM factors are mainly reported to have a direct effect on cell…”
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SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion by Gallotta, Marilena, Gancitano, Giovanni, Pietrocola, Giampiero, Mora, Marirosa, Pezzicoli, Alfredo, Tuscano, Giovanna, Chiarot, Emiliano, Nardi-Dei, Vincenzo, Taddei, Anna Rita, Rindi, Simonetta, Speziale, Pietro, Soriani, Marco, Grandi, Guido, Margarit, Immaculada, Bensi, Giuliano

“…Group A streptococcus (GAS) is a human pathogen causing a wide repertoire of mild and severe diseases for which no vaccine is yet available. We recently…”
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Relevance of pili in pathogenic streptococci pathogenesis and vaccine development by Soriani, Marco, Telford, John L

“…A common mechanism used by bacteria to initiate adhesion to host tissues during colonization is the expression of long filamentous structures extending from…”
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The Neisseria meningitidis ADP-Ribosyltransferase NarE Enters Human Epithelial Cells and Disrupts Epithelial Monolayer Integrity by Valeri, Maria, Zurli, Vanessa, Ayala, Inmaculada, Colanzi, Antonino, Lapazio, Lucia, Corda, Daniela, Soriani, Marco, Pizza, Mariagrazia, Rossi Paccani, Silvia

“…Many pathogenic bacteria utilize ADP-ribosylating toxins to modify and impair essential functions of eukaryotic cells. It has been previously reported that…”
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Protective Efficacy Induced by Recombinant Clostridium difficile Toxin Fragments by Leuzzi, Rosanna, Spencer, Janice, Buckley, Anthony, Brettoni, Cecilia, Martinelli, Manuele, Tulli, Lorenza, Marchi, Sara, Luzzi, Enrico, Irvine, June, Candlish, Denise, Veggi, Daniele, Pansegrau, Werner, Fiaschi, Luigi, Savino, Silvana, Swennen, Erwin, Cakici, Osman, Oviedo-Orta, Ernesto, Giraldi, Monica, Baudner, Barbara, D'Urzo, Nunzia, Maione, Domenico, Soriani, Marco, Rappuoli, Rino, Pizza, Mariagrazia, Douce, Gillian R, Scarselli, Maria

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Adaptive response of Group B streptococcus to high glucose conditions: new insights on the CovRS regulation network by Di Palo, Benedetta, Rippa, Valentina, Santi, Isabella, Brettoni, Cecilia, Muzzi, Alessandro, Metruccio, Matteo Maria Emiliano, Grifantini, Renata, Telford, John L, Paccani, Silvia Rossi, Soriani, Marco

“…Although the contribution of carbohydrate catabolism to bacterial colonization and infection is well recognized, the transcriptional changes during these…”
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Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin by Fiaschi, Luigi, Di Palo, Benedetta, Scarselli, Maria, Pozzi, Clarissa, Tomaszewski, Kelly, Galletti, Bruno, Nardi-Dei, Vincenzo, Arcidiacono, Letizia, Mishra, Ravi P N, Mori, Elena, Pallaoro, Michele, Falugi, Fabiana, Torre, Antonina, Fontana, Maria Rita, Soriani, Marco, Bubeck Wardenburg, Juliane, Grandi, Guido, Rappuoli, Rino, Ferlenghi, Ilaria, Bagnoli, Fabio

“…Staphylococcus aureus alpha-hemolysin (Hla) assembles into heptameric pores on the host cell membrane, causing lysis, apoptosis, and junction disruption…”
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Group B Streptococcus Pullulanase Crystal Structures in the Context of a Novel Strategy for Vaccine Development by GOURLAY, Louise J, SANTI, Isabella, PEZZICOLI, Alfredo, GRANDI, Guido, SORIANI, Marco, BOLOGNESI, Martino

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