Search Results - "Sorgenfrei, Frieda A."

Boronate affinity electrophoresis for the purification and analysis of cofactor-modified RNAs by Nübel, Gabriele, Sorgenfrei, Frieda A., Jäschke, Andres

“…•Boronic acid-modified polyacrylamide gels retard NAD-RNA compared to unmodified RNAs.•In vitro transcribed NAD-RNA can be purified on boronic acid-modified…”
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Solvent concentration at 50% protein unfolding may reform enzyme stability ranking and process window identification by Sorgenfrei, Frieda A., Sloan, Jeremy J., Weissensteiner, Florian, Zechner, Marco, Mehner, Niklas A., Ellinghaus, Thomas L., Schachtschabel, Doreen, Seemayer, Stefan, Kroutil, Wolfgang

“…As water miscible organic co-solvents are often required for enzyme reactions to improve e.g., the solubility of the substrate in the aqueous medium, an enzyme…”
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Kinome‐Wide Profiling Prediction of Small Molecules by Sorgenfrei, Frieda A., Fulle, Simone, Merget, Benjamin

“…Extensive kinase profiling data, covering more than half of the human kinome, are available nowadays and allow the construction of activity prediction models…”
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Kinetic and structural roles for the surface in guiding SAS-6 self-assembly to direct centriole architecture by Banterle, Niccolò, Nievergelt, Adrian P., de Buhr, Svenja, Hatzopoulos, Georgios N., Brillard, Charlène, Andany, Santiago, Hübscher, Tania, Sorgenfrei, Frieda A., Schwarz, Ulrich S., Gräter, Frauke, Fantner, Georg E., Gönczy, Pierre

“…Discovering mechanisms governing organelle assembly is a fundamental pursuit in biology. The centriole is an evolutionarily conserved organelle with a…”
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The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved by Karlsson, Elin, Sorgenfrei, Frieda A., Andersson, Eva, Dogan, Jakob, Jemth, Per, Chi, Celestine N.

“…Evolution of proteins is constrained by their structure and function. While there is a consensus that the plasticity of intrinsically disordered proteins…”
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Transmembrane Shuttling of Photosynthetically Produced Electrons to Propel Extracellular Biocatalytic Redox Reactions in a Modular Fashion by Jurkaš, Valentina, Weissensteiner, Florian, De Santis, Piera, Vrabl, Stephan, Sorgenfrei, Frieda A., Bierbaumer, Sarah, Kara, Selin, Kourist, Robert, Wangikar, Pramod P., Winkler, Christoph K., Kroutil, Wolfgang

“…Many biocatalytic redox reactions depend on the cofactor NAD(P)H, which may be provided by dedicated recycling systems. Exploiting light and water for…”
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Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins by Karlsson, Elin, Paissoni, Cristina, Erkelens, Amanda M., Tehranizadeh, Zeinab A., Sorgenfrei, Frieda A., Andersson, Eva, Ye, Weihua, Camilloni, Carlo, Jemth, Per

“…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
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PQQ‐dependent Dehydrogenase Enables One‐pot Bi‐enzymatic Enantio‐convergent Biocatalytic Amination of Racemic sec‐Allylic Alcohols by Gandomkar, Somayyeh, Rocha, Raquel, Sorgenfrei, Frieda A., Montero, Lía Martínez, Fuchs, Michael, Kroutil, Wolfgang

“…The asymmetric amination of secondary racemic allylic alcohols bears several challenges like the reactivity of the bi‐functional substrate/product as well as…”
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Folding Optimization In Vivo Uncovers New Chaperones by Lennon, Christopher W., Thamsen, Maike, Friman, Elias T., Cacciaglia, Austin, Sachsenhauser, Veronika, Sorgenfrei, Frieda A., Wasik, Milena A., Bardwell, James C.A.

“…By employing a genetic selection that forces the cell to fold an unstable, aggregation-prone test protein in order to survive, we have generated bacterial…”
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Transmembrane Shuttling of Photosynthetically Produced Electrons to Propel Extracellular Biocatalytic Redox Reactions in a Modular Fashion by Jurkaš, Valentina, Weissensteiner, Florian, De Santis, Piera, Vrabl, Stephan, Sorgenfrei, Frieda A., Bierbaumer, Sarah, Kara, Selin, Kourist, Robert, Wangikar, Pramod P., Winkler, Christoph K., Kroutil, Wolfgang

“…Many biocatalytic redox reactions depend on the cofactor NAD(P)H, which may be provided by dedicated recycling systems. Exploiting light and water for…”
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Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins by Karlsson, Elin, Paissoni, Cristina, Erkelens, Amanda M., Tehranizadeh, Zeinab A., Sorgenfrei, Frieda A., Andersson, Eva, Ye, Weihua, Camilloni, Carlo, Jemth, Per

“…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
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Cover Feature: PQQ‐dependent Dehydrogenase Enables One‐pot Bi‐enzymatic Enantio‐convergent Biocatalytic Amination of Racemic sec‐Allylic Alcohols (5/2021) by Gandomkar, Somayyeh, Rocha, Raquel, Sorgenfrei, Frieda A., Montero, Lía Martínez, Fuchs, Michael, Kroutil, Wolfgang

“…The Cover Feature picture shows an assembly line as a cartoon for the biocatalytic cascade described in the Communication by S. Gandomkar et al. The racemic…”
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Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins by Karlsson, Elin, Paissoni, Cristina, Erkelens, Amanda M, Tehranizadeh, Zeinab A, Sorgenfrei, Frieda A, Andersson, Eva, Ye, Weihua, Camilloni, Carlo, Jemth, Per

“…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
Get full text