Search Results - "Sorg, Barbara A"

Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity by Sorg, Barbara A, Berretta, Sabina, Blacktop, Jordan M, Fawcett, James W, Kitagawa, Hiroshi, Kwok, Jessica C F, Miquel, Marta

“…Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain neurons in the CNS during development and control plasticity in…”
Get full text

Impact of Perineuronal Nets on Electrophysiology of Parvalbumin Interneurons, Principal Neurons, and Brain Oscillations: A Review by Wingert, Jereme C., Sorg, Barbara A.

“…Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround specific neurons in the brain and spinal cord, appear during critical…”
Get full text

The extracellular matrix and perineuronal nets in memory by Fawcett, James W., Fyhn, Marianne, Jendelova, Pavla, Kwok, Jessica C. F., Ruzicka, Jiri, Sorg, Barbara A.

“…All components of the CNS are surrounded by a diffuse extracellular matrix (ECM) containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate…”
Get full text

Impact of Environmental Enrichment on Perineuronal Nets in the Prefrontal Cortex following Early and Late Abstinence from Sucrose Self-Administration in Rats by Slaker, Megan, Barnes, Jesse, Sorg, Barbara A, Grimm, Jeffrey W

“…Perineuronal nets (PNNs) are aggregates of extracellular matrix that form structures surrounding a subset of GABAergic interneurons. The staining intensity of…”
Get full text

Removal of perineuronal nets in the medial prefrontal cortex impairs the acquisition and reconsolidation of a cocaine-induced conditioned place preference memory by Slaker, Megan, Churchill, Lynn, Todd, Ryan P, Blacktop, Jordan M, Zuloaga, Damian G, Raber, Jacob, Darling, Rebecca A, Brown, Travis E, Sorg, Barbara A

“…Pyramidal neurons in the medial prefrontal cortex (mPFC) critically contribute to cocaine-seeking behavior in humans and rodents. Activity of these neurons is…”
Get full text

Role of perineuronal nets in the anterior dorsal lateral hypothalamic area in the acquisition of cocaine-induced conditioned place preference and self-administration by Blacktop, Jordan M., Todd, Ryan P., Sorg, Barbara A.

“…Addiction involves drug-induced neuroplasticity in the circuitry of motivated behavior, which includes the medial forebrain bundle and the lateral hypothalamic…”
Get full text

A Systematic Review of Extracellular Matrix-Related Alterations in Parkinson's Disease by Chapman, Mary Ann, Sorg, Barbara A

“…The role of the extracellular matrix (ECM) in Parkinson's disease (PD) is not well understood, even though it is critical for neuronal structure and signaling…”
Get full text

In Vivo Cocaine Experience Generates Silent Synapses by Huang, Yanhua H., Lin, Ying, Mu, Ping, Lee, Brian R., Brown, Travis E., Wayman, Gary, Marie, Helene, Liu, Wenhua, Yan, Zhen, Sorg, Barbara A., Schlüter, Oliver M., Zukin, R. Suzanne, Dong, Yan

“…Studies over the past decade have enunciated silent synapses as prominent cellular substrates for synaptic plasticity in the developing brain. However, little…”
Get full text

Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex by Harkness, John H., Gonzalez, Angela E., Bushana, Priyanka N., Jorgensen, Emily T., Hegarty, Deborah M., Di Nardo, Ariel A., Prochiantz, Alain, Wisor, Jonathan P., Aicher, Sue A., Brown, Travis E., Sorg, Barbara A.

“…Perineuronal nets (PNNs) surrounding fast-spiking, parvalbumin (PV) interneurons provide excitatory:inhibitory balance, which is impaired in several disorders…”
Get full text

A silent synapse-based mechanism for cocaine-induced locomotor sensitization by Brown, Travis E, Lee, Brian R, Mu, Ping, Ferguson, Deveroux, Dietz, David, Ohnishi, Yoshinori N, Lin, Ying, Suska, Anna, Ishikawa, Masago, Huang, Yanhua H, Shen, Haowei, Kalivas, Peter W, Sorg, Barbara A, Zukin, R Suzanne, Nestler, Eric J, Dong, Yan, Schlüter, Oliver M

“…Locomotor sensitization is a common and robust behavioral alteration in rodents whereby following exposure to abused drugs such as cocaine, the animal becomes…”
Get full text

Impact of Perineuronal Net Removal in the Rat Medial Prefrontal Cortex on Parvalbumin Interneurons After Reinstatement of Cocaine Conditioned Place Preference by Gonzalez, Angela E., Jorgensen, Emily T., Ramos, Jonathan D., Harkness, John H., Aadland, Jake A., Brown, Travis E., Sorg, Barbara A.

“…Parvalbumin (PV)-positive cells are GABAergic fast-spiking interneurons that modulate the activity of pyramidal neurons in the medial prefrontal cortex (mPFC)…”
Get full text

Exposure to Cocaine Dynamically Regulates the Intrinsic Membrane Excitability of Nucleus Accumbens Neurons by Mu, Ping, Moyer, Jason T, Ishikawa, Masago, Zhang, Yonghong, Panksepp, Jaak, Sorg, Barbara A, Schluter, Oliver M, Dong, Yan

“…Drug-induced malfunction of nucleus accumbens (NAc) neurons underlies a key pathophysiology of drug addiction. Drug-induced changes in intrinsic membrane…”
Get full text

Caught in the Net: Perineuronal Nets and Addiction by Slaker, Megan, Sorg, Barbara A., Blacktop, Jordan M.

“…Exposure to drugs of abuse induces plasticity in the brain and creates persistent drug-related memories. These changes in plasticity and persistent drug…”
Get full text

Diurnal differences in dopamine transporter and tyrosine hydroxylase levels in rat brain: Dependence on the suprachiasmatic nucleus by Sleipness, Evan P, Sorg, Barbara A, Jansen, Heiko T

“…Abstract Time of day can influence cocaine-seeking behavior in rats, and this influence may depend on the suprachiasmatic nucleus (SCN). We used western blots…”
Get full text

Enhanced memory persistence is blocked by a DNA methyltransferase inhibitor in the snail Lymnaea stagnalis by Lukowiak, Ken, Heckler, Benjamin, Bennett, Thomas E, Schriner, Ellen K, Wyrick, Kathryn, Jewett, Cynthia, Todd, Ryan P, Sorg, Barbara A

“…Lymnaea stagnalis provides an excellent model system for studying memory because these snails have a well-described set of neurons, a single one of which…”
Get full text

Effect of N-Acetylcysteine on Sleep: Impacts of Sex and Time of Day by Bushana, Priyanka N, Schmidt, Michelle A, Chang, Kevin M, Vuong, Trisha, Sorg, Barbara A, Wisor, Jonathan P

“…Non-rapid eye movement sleep (NREMS) is accompanied by a decrease in cerebral metabolism, which reduces the consumption of glucose as a fuel source and…”
Get full text

Reconsolidation of drug memories by SORG, Barbara A

“…Persistent, unwanted memories are believed to be key contributors to drug addiction and the chronic relapse problem over the lifetime of the addict. Contrary…”
Get full text

Circadian discrimination of reward: evidence for simultaneous yet separable food- and drug-entrained rhythms in the rat by Jansen, Heiko T, Sergeeva, Anna, Stark, Gemaine, Sorg, Barbara A

“…A unique extra-suprachiasmatic nucleus (SCN) oscillator, operating independently of the light-entrainable oscillator, has been hypothesized to generate feeding…”
Get more information

Role of Matrix Metalloproteinases in the Acquisition and Reconsolidation of Cocaine-Induced Conditioned Place Preference by Brown, Travis E, Forquer, Melissa R, Cocking, Davelle L, Jansen, Heiko T, Harding, Joseph W, Sorg, Barbara A

“…Persistent drug seeking/taking behavior involves the consolidation of memory. With each drug use, the memory may be reactivated and reconsolidated to maintain…”
Get full text

Net gain and loss: influence of natural rewards and drugs of abuse on perineuronal nets by Brown, Travis E, Sorg, Barbara A

“…Overindulgence, excessive consumption, and a pattern of compulsive use of natural rewards, such as certain foods or drugs of abuse, may result in the…”
Get full text