Search Results - "Sorensen, Peter Grundtvig"

Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment by Rolfo, Christian, de Vos-Geelen, Judith, Isambert, Nicolas, Molife, L. Rhoda, Schellens, Jan H. M., De Grève, Jacques, Dirix, Luc, Grundtvig-Sørensen, Peter, Jerusalem, Guy, Leunen, Karin, Mau-Sørensen, Morten, Plummer, Ruth, Learoyd, Maria, Bannister, Wendy, Fielding, Anitra, Ravaud, Alain

“…Background Olaparib, a potent oral poly(ADP-ribose) polymerase inhibitor, is partially renally cleared. We investigated the pharmacokinetics and safety of…”
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Pharmacokinetic Effects and Safety of Olaparib Administered with Endocrine Therapy: A Phase I Study in Patients with Advanced Solid Tumours by Plummer, Ruth, Verheul, Henk M., De Vos, Filip Y. F. L., Leunen, Karin, Molife, L. Rhoda, Rolfo, Christian, Grundtvig-Sørensen, Peter, De Grève, Jacques, Rottey, Sylvie, Jerusalem, Guy, Italiano, Antoine, Spicer, James, Dirix, Luc, Goessl, Carsten, Birkett, Joseph, Spencer, Stuart, Learoyd, Maria, Bailey, Christopher, Dean, Emma

“…Introduction The PARP inhibitor olaparib is efficacious as monotherapy and has potential application in combination with endocrine therapy for the treatment of…”
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An open label phase 1 study evaluation safety, tolerability, and maximum tolerated dose of oral administration of irinotecan in combination with capecitabine by Kümler, I., Eefsen, R. L., Sørensen, Peter Grundtvig, Theile, S., Fullerton, A., Nielsen, P. G., Jensen, Benny Vittrup, Nielsen, D. L.

“…Purpose Oral administration of chemotherapy offers several advantages in comparison with intravenous administration. Previously, data on a new oral formulation…”
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Mediators of inflammation correlate with microalbuminuria in patients with non‐Hodgkin's lymphoma by Pedersen, Lars Møller, Sørensen, Peter Grundtvig

“…Recent studies have demonstrated a high frequency of minor glomerular leakage of albumin in cancer patients. Pathogenic mechanisms of increased urinary albumin…”
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Urinary Albumin Excretion is a Predictor of Response to Treatment and Disease Progression in Low-Grade non-Hodgkin's Lymphoma by Pedersen, Lars Møller, Sørensen, Peter Grundtvig

“…Slightly increased urinary albumin excretion (UAE) is frequently found in patients with malignant diseases and is associated with adverse prognostic factors…”
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Clinical significance of urinary albumin excretion in patients with non‐Hodgkin's lymphoma by Pedersen, Lars Møller, Sørensen, Peter Grundtvig

“…Slightly increased urinary albumin excretion rates (UAE) have been reported in patients with various types of human cancer. We measured UAE in 24 h urine…”
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Prolonged bone marrow T1-relaxation in acute leukaemia. In vivo tissue characterization by magnetic resonance imaging by Thomsen, C, Sørensen, P G, Karle, H, Christoffersen, P, Henriksen, O

“…In vivo tissue characterization by measurement of T1- and T2-relaxation processes is one of the greatest potentials of magnetic resonance imaging (MRI). This…”
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Prolonged bone marrow T1-relaxation in patients with polycythemia vera by Jensen, K E, Grube, T, Thomsen, C, Sørensen, P G, Christoffersen, P, Karle, H, Henriksen, O

“…In vitro as well as in vivo studies have shown prolonged T1 relaxation times in patients with acute leukemia. The mechanism behind this finding is not known…”
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Beta-2-microglobulin excretion: an indicator of long term nephrotoxicity during cis-platinum treatment? by SØRENSEN, P. G, NISSEN, M. H, GROTH, S, RØRTH, M

“…To evaluate the value of beta-2-microglobulin as an indicator of acute and long-term cis-platinum-induced nephrotoxicity, 51Cr-EDTA clearance and serum…”
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Regional lung function impairment following post-operative radiotherapy for breast cancer using direct or tangential field techniques by Groth, S, Zaric, A, Sørensen, P B, Larsen, J, Sørensen, P G, Rossing, N

“…We have compared the effect of tangential and direct irradiation on regional lung function in 22 consecutive patients with breast cancer, who had been treated…”
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Angiotensin-converting enzyme: an indicator of bleomycin-induced pulmonary toxicity in humans? by Sørensen, P G, Rømer, F K, Cortes, D

“…In order to evaluate bleomycin-associated lung damage in humans, lung function parameters and serum levels of the endothelial-bound angiotensin-converting…”
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